Protein Alignment kat-60L1 and knk1

DIOPT Version :10

• Sequence 1: NP_001163523.1
• Gene: kat-60L1 / 40715
• FlyBaseID: FBgn0037375
• Length: 673
• Species: Drosophila melanogaster
• Sequence 2: NP_595275.1
• Gene: knk1 / 2541249
• PomBaseID: SPBC947.01
• Length: 660
• Species: Schizosaccharomyces pombe
• Alignment Length: 701
• Identity: 217/701 - (30%)
• Similarity: 328/701 - (46%)
• Gaps: 134/701 - (19%)

  Fly     6 AQNWFGMGQTAVDPSGGV------AQLLNNNSSLYNQQQQQAAAAQHSFMRQRSLTSS-NPVLGR 63
            |.:|.|:....:..:..:      :::...|..|..:..::|....|.....||.|.: .|:..|
pombe    58 ACSWNGLYDNCLSKASKLRKTILESEMERQNYQLAAKLSKKAPVDLHPLRPVRSQTPAYTPMTTR 122

  Fly    64 SNALATRPQSPPNVQVEYEVAVPFVPTYRHTPYHSLWDLHQCSSTPPTSLSHMARMMDSLILDSL 128
            .....||     ..|.|..::.|.....:|:|             |.||.|.:..
pombe   123 MMYRQTR-----GAQSEVNLSTPKQIYSKHSP-------------PSTSTSSIVS---------- 159

  Fly   129 SPFG-FTKITATSRPSRNASLKKSSEGGHSSTAERHRPVNNLGSNAPGGLGIGGSVPLRSKQRLP 192
            |.:| .....|.|:|:|:..||...            |..:..|:|       .::...||.
pombe   160 SSYGDAPSYLAPSKPNRSPPLKPED------------PFASFNSSA-------SAIAAASKS--- 202

  Fly   193 TQVSAAEVAPQPRASQTA-QMPFPSQQQDNRWVSSLRRRDPELQPTLPSINSNANSSSLSQSHHG 256
            ...||:.::.....|.|. ...||:..:..             ..|.|:::::.:|.|:..|::.
pombe   203 AAASASALSSDTGRSATMNSTTFPTAMKSQ-------------STTKPTLSNSVSSPSIQVSNNQ 254

  Fly   257 SAGNVGLAGAGAPTPAASMGTMRLGRPARASAMTAALRKSRSVERLRARKLSTNTQLNLKHKPVK 321
            :|.|.......||.|...:..:    |..:::.:::..|||                  ||....
pombe   255 NANNSTPLSFHAPIPPLHVPAV----PLTSASHSSSDGKSR------------------KHPSPY 297

  Fly   322 KNSLDENSNSDDQDATTSLEDNSHAQSLATSHNTPKCSPKTKAKHFS--------PLGYEVHLVD 378
            |..|  ||:.|...::|.......|.|.|||......|....:|..|        ||.......|
pombe   298 KPYL--NSSHDTLGSSTRPSSADTAGSPATSPPATADSKTIVSKTISASTTQQTEPLQQTTPSSD 360

  Fly   379 ---TLEKDILQRHPCIKWTDVAGLNEAKTILQEAVVLPVIMPEFFKGIRRPWRGVLMVGPPGTGK 440
               .:..:|:..|..:.|:|:|||::||..|:|||:.|.:.||.|:|:|.|.:|:|:.|||||||
pombe   361 FEYAIMNEIISNHEPVYWSDIAGLDDAKNSLKEAVIYPFLRPELFQGLREPVQGMLLFGPPGTGK 425

  Fly   441 TMLAKAVATECGTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYAPSTIFIDEIDALCASRG-S 504
            ||||:|||||...|||::|:|:|||||.|:||||||.|||:|:....|.||:||||::.::|. |
pombe   426 TMLARAVATEAKATFFSISASSLTSKYLGDSEKLVRALFEVAKRQTCSVIFVDEIDSILSARNDS 490

  Fly   505 DSEHEASRRFKAELLIQMDGLNASMQEEKV-----IMVLAATNHPWDIDEAFRRRFEKRIYIPLP 564
            .:|||:|||.|.|.|||...|..:..:::.     ::||||||.||.||||.||||.||.|||||
pombe   491 GNEHESSRRLKTEFLIQWSSLTNAAPDKQTGHSPRVLVLAATNLPWCIDEAARRRFVKRTYIPLP 555

  Fly   565 NEGTR----SALLK---LCLKDVCLSPSLNTGIIGDELQGYSGSDISNVCRDASMMAMRRLISGR 622
            .:.||    |.||.   .||.:..|...:|.      .:|||||||:.:.:||:|..:|.|
pombe   556 EKETRYKHLSHLLHNQVHCLTEEDLEELVNL------TEGYSGSDITALAKDAAMGPLRNL---- 610

  Fly   623 TPDQIKQIRREEVDQPITLQDFQDARLRT-KKSVSADDVARFEKWMEEYGS 672
             .|.:.....|.: .||:|..|: |.||| :.|||.:.:.|:|:|.:::||
pombe   611 -GDALLTTSAEMI-PPISLNHFK-ASLRTIRPSVSQEGIHRYEEWNKQFGS 658

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kat-60L1	NP_001163523.1	P-loop containing Nucleoside Triphosphate Hydrolases	395..561	CDD:476819	95/171 (56%)
		AAA_lid_3	591..629	CDD:465537	13/37 (35%)
		Vps4_C	<638..671	CDD:462762	14/33 (42%)
knk1	NP_595275.1	Herpes_BLLF1	<221..>359	CDD:282904	34/174 (20%)
		RecA-like_VPS4-like	381..552	CDD:410917	94/170 (55%)
		AAA_lid_3	577..614	CDD:465537	15/47 (32%)
		Vps4_C	<623..657	CDD:462762	14/34 (41%)