Protein Alignment kat-60L1 and spas-1

DIOPT Version :10

• Sequence 1: NP_001163523.1
• Gene: kat-60L1 / 40715
• FlyBaseID: FBgn0037375
• Length: 673
• Species: Drosophila melanogaster
• Sequence 2: NP_001256115.1
• Gene: spas-1 / 179300
• WormBaseID: WBGene00016045
• Length: 512
• Species: Caenorhabditis elegans
• Alignment Length: 529
• Identity: 170/529 - (32%)
• Similarity: 262/529 - (49%)
• Gaps: 97/529 - (18%)

  Fly   181 GSVPLRSKQRLPTQVSAAEVAPQPR-----ASQTAQMPFP----SQQQDNRWVSSLRRRDPELQP 236
            ||:    :::|.|    ||:..:.|     |::...|..|    |:.:|.|  .::.:.:...|.
 Worm    42 GSI----QEKLRT----AELYKEARSLLKEANEFNIMDIPETRRSEIRDKR--QNMMKLEKSAQD 96

  Fly   237 TLPSINSNANSSSLSQSHHGSAGNVGLAGAGAPTPAASMGTMRLGRPARASA---MTAALRKSRS 298
            .|.:| .|....::.||...:.|....|.|...||          ||.||:|   ..||..|...
 Worm    97 RLIAI-CNEVDPNVKQSRSATVGPSRPASAARVTP----------RPTRATAPEKKNAAKAKEND 150

  Fly   299 VERLRARKLSTNTQLNLKHKPVKKNSLDENSNSDDQDATTSLEDNSHAQSLATSHN----TPKCS 359
            ..|   ...|...:....|:||.|.|                 |..|.:....:.|    |.|..
 Worm   151 ENR---HVCSRGDRCGAHHQPVTKKS-----------------DTVHPEPPVQASNRKMETVKRV 195

  Fly   360 PKTKAK---HFSPLGYEVHLVDTLEKDILQR-------HPCIKWTDVAGLNEAKTILQEAVVLPV 414
            ...||.   |.:|:. ...|::.::|.|.:|       :..::..||||.:.||..|:|||:||.
 Worm   196 KVDKASLPMHQNPVN-RAALLNGVDKVIGERLLDEVLDNTGVRMDDVAGCHSAKAALEEAVILPA 259

  Fly   415 IMPEFFKGIRRPWRGVLMVGPPGTGKTMLAKAVATECGTTFFNVSSSTLTSKYRGESEKLVRLLF 479
            :.|..|||:|:|.:|:|:.||||.|||:||||||.|....|||:|:|:||||:.|:|||.:|.||
 Worm   260 LNPNLFKGLRQPVKGILLFGPPGNGKTLLAKAVAGESKQMFFNISASSLTSKWVGDSEKTIRGLF 324

  Fly   480 EMARFYAPSTIFIDEIDALCASRGSDSEHEASRRFKAELLIQMDGLNASMQEEKVIMVLAATNHP 544
            ::||...||.|||||||::...| |:.:.|.|||.|.|.|:|.||..:|..:.  |:|:.|||.|
 Worm   325 QIARNAQPSIIFIDEIDSILCER-SEKDAEVSRRMKTEFLVQFDGATSSADDR--ILVIGATNRP 386

  Fly   545 WDIDEAFRRRFEKRIYIPLPNEGTRSALLKLCLKDVCLSPSLNTGIIGDELQ-------GYSGSD 602
            .::|:|..|||.|||.:.||:|..|..|:...||    ..::..|:|..:::       |:|.||
 Worm   387 HELDDAVLRRFPKRIMLNLPDEEARKELITKTLK----KHNMMDGLISSDIRYIASNTSGFSNSD 447

  Fly   603 ISNVCRDASMMAMRRL----ISGRTPDQIKQIRREEVDQPITLQDFQDARLRT-KKSVSADDVAR 662
            :..:|::|:|:.:|.:    :|....::|::||         ..|| |..||| :.|.|...:::
 Worm   448 LVALCKEAAMVPIREIDRSKLSMTDGEKIRKIR---------ASDF-DTALRTIRPSTSQKIMSK 502

  Fly   663 FEKWMEEYG 671
            ...:...:|
 Worm   503 LSDFSRSFG 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kat-60L1	NP_001163523.1	P-loop containing Nucleoside Triphosphate Hydrolases	395..561	CDD:476819	88/165 (53%)
		AAA_lid_3	591..629	CDD:465537	11/48 (23%)
		Vps4_C	<638..671	CDD:462762	8/33 (24%)
spas-1	NP_001256115.1	cell_div_CdvC	175..510	CDD:468935	129/352 (37%)
		P-loop containing Nucleoside Triphosphate Hydrolases	240..401	CDD:476819	86/163 (53%)