Protein Alignment kat-60L1 and mei-1

DIOPT Version :10

• Sequence 1: NP_001163523.1
• Gene: kat-60L1 / 40715
• FlyBaseID: FBgn0037375
• Length: 673
• Species: Drosophila melanogaster
• Sequence 2: NP_001370150.1
• Gene: mei-1 / 172612
• WormBaseID: WBGene00003183
• Length: 475
• Species: Caenorhabditis elegans
• Alignment Length: 542
• Identity: 173/542 - (31%)
• Similarity: 265/542 - (48%)
• Gaps: 102/542 - (18%)

  Fly   155 GHSSTAERHRPVNNLGS-NAPGGLGIGGSVPLRSKQRLPTQVSAAEVAPQPRASQTAQMPFPSQQ 218
            |:...|:..:.:::.|. |..|.|       ||   :|.|.|.:.:::...|....|:..|....
 Worm    11 GYLERAQVAKTMSDAGRWNEAGDL-------LR---QLMTDVKSCKISASNRDEHDARNTFLRAL 65

  Fly   219 QDNRWVSSLRRRD--------------PELQPTLPSINSNANSSSLSQSHHGSAGNVGLAGAGAP 269
            :.|..:.....||              || .|..|.:.|..:....|.|..|:...    |.||.
 Worm    66 EANLKLVQQNVRDEDDLHEAMTRQSGSPE-PPADPDVWSKPSPPLPSSSKFGATKK----GVGAA 125

  Fly   270 TPAASMGTMRLGRPARASAMTAALRKSRSVERLRARKLSTNTQLNLKHKPVKKNSLDENSNSDDQ 334
            .|          ||...|..|::              :||| ..::|.....:..|.:||..|..
 Worm   126 GP----------RPREISKSTSS--------------MSTN-PADVKPANPTQGILPQNSAGDSF 165

  Fly   335 DATTSLEDNSHAQSLATSHNTPKCSPKTKAKHFSPLGYEVHLVDTLEKDI-LQRHPCIKWTDVAG 398
            ||:                                 .|:.::|..:...: ......:...|:.|
 Worm   166 DAS---------------------------------AYDAYIVQAVRGTMATNTENTMSLDDIIG 197

  Fly   399 LNEAKTILQEAVVLPVIMPEFFKGIRRPWRGVLMVGPPGTGKTMLAKAVATECGTTFFNVSSSTL 463
            :::.|.:|.|||.||:::||||:|:|.||:.:::.||||||||::|:|:|:|..:|||.|||:.|
 Worm   198 MHDVKQVLHEAVTLPLLVPEFFQGLRSPWKAMVLAGPPGTGKTLIARAIASESSSTFFTVSSTDL 262

  Fly   464 TSKYRGESEKLVRLLFEMARFYAPSTIFIDEIDALCASRGSDSEHEASRRFKAELLIQMDGLNAS 528
            :||:||:|||:||||||:|||||||.|||||||.|...||:..|||||||.|:|.|:||||....
 Worm   263 SSKWRGDSEKIVRLLFELARFYAPSIIFIDEIDTLGGQRGNSGEHEASRRVKSEFLVQMDGSQNK 327

  Fly   529 MQEEKVIMVLAATNHPWDIDEAFRRRFEKRIYIPLPNEGTRSALLKLCLKDVCLSPSLNTGIIGD 593
            ....:| .||||||.||::|||.||||||||:||||:...|..|::..::....|..:|...:..
 Worm   328 FDSRRV-FVLAATNIPWELDEALRRRFEKRIFIPLPDIDARKKLIEKSMEGTPKSDEINYDDLAA 391

  Fly   594 ELQGYSGSDISNVCRDASMMAMRR--------LISGRTPDQIKQIRREEVDQPITLQDFQDARLR 650
            ..:|:||:|:.::||.|::..:||        |..|.....::.::.|.|..    .||:.|...
 Worm   392 RTEGFSGADVVSLCRTAAINVLRRYFRYDTKSLRGGELTAAMESLKAELVRN----IDFEAALQA 452

  Fly   651 TKKSVSADDVARFEKWMEEYGS 672
            ...|...|.:.:.::|.:.:|:
 Worm   453 VSPSAGPDTMLKCKEWCDSFGA 474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kat-60L1	NP_001163523.1	P-loop containing Nucleoside Triphosphate Hydrolases	395..561	CDD:476819	100/165 (61%)
		AAA_lid_3	591..629	CDD:465537	11/45 (24%)
		Vps4_C	<638..671	CDD:462762	6/32 (19%)
mei-1	NP_001370150.1	SpoVK	53..414	CDD:440232	148/424 (35%)
		RecA-like_VPS4-like	195..359	CDD:410917	99/164 (60%)