DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2082 and ndrg3b

DIOPT Version :9

Sequence 1:	NP_001163513.1	Gene:	CG2082 / 40713	FlyBaseID:	FBgn0027608	Length:	368	Species:	Drosophila melanogaster
Sequence 2:	XP_009294966.1	Gene:	ndrg3b / 327395	ZFINID:	ZDB-GENE-030131-5606	Length:	390	Species:	Danio rerio

Alignment Length:	362	Identity:	102/362 - (28%)
Similarity:	164/362 - (45%)	Gaps:	60/362 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 KYNISTEKCGDLTVIVQGDLSQQEKRAVFITVHDLGCNHNS-FQEFVSSPCMTEIKERSCFIHVD 88
            :::|.|.: |.|.|.::|  :.:..|.|.:|.||:|.||.| |....:...|.||.:....:|||
Zfish    32 EHDIETPR-GVLHVTLRG--TPKGNRPVILTYHDIGLNHKSCFNTLFNFEDMQEITQHFAVVHVD 93

  Fly    89 VPGHADNAEALADGFPFPSLQSLGEDLVTVLDYLHVKYVIGLGEGAGANVLARFGLAHPSRVLGL 153
            .||..::|.....||.:|::..|.|.|.:||.:|.:..|||:|.||||.:|.||.|..|:.|.||
Zfish    94 APGQQESAPPFPTGFLYPTMDELAEMLPSVLTHLKINSVIGIGVGAGAYILTRFALNEPALVEGL 158

  Fly   154 ILINATGSAASVVQSFKNKFISWKSDEVAQSAESFLMYHKFGHVMEQIVGENPDKEKIVAEYQKR 218
            :|||....|...:....:|...|.|:.:     ..:|.|.|.      ..|..:.::|:..|:..
Zfish   159 VLINVDPCAKGWIDWAASKLSGWTSNLI-----DIVMAHHFS------TDELTENQEIIQTYRLH 212

  Fly   219 LHRSLNSKNIGLYVKAFMNRKDL------------TLKGCKVDVILITGMLSPYASMVEKLHRDV 271
            :.:.:|..|:.|:.:::.:|:||            .:|..|...:||.|..||....|.:.:..:
Zfish   213 IAQDINQDNLALFCQSYNSRRDLEIERPVLGMNENAVKTLKCPALLIVGDTSPAVEAVVECNSRL 277

  Fly   272 EKERVTILKIERAGDV-LADAPGKVAQSILLFCKGQG-LLTSVVMPGV----------------- 317
            ...:.|:||:...|.: ....|||:|::...|.:|.| ::.|...|.|
Zfish   278 NPTKTTLLKMADCGGLPQVVQPGKLAEAFKYFVQGMGYMMRSSAFPHVLLSHLNSESVPTASMTR 342

  Fly   318 -DRGRAFSTASSGS-------------LEGANGSRRL 340
             .|.|..|.:|.||             :|||.|...|
Zfish   343 LARSRTHSASSMGSGDGSRSRTQTSSQMEGATGGPAL 379

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2082	NP_001163513.1	Abhydrolase	26..310	CDD:419691	88/298 (30%)
ndrg3b	XP_009294966.1	Ndr	32..316	CDD:251726	88/297 (30%)
ndrg3b	XP_009294966.1	MhpC	42..312	CDD:223669	83/282 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595960
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D359278at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11034
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5286
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.980