DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2082 and Ndrg3

DIOPT Version :9

Sequence 1:	NP_001163513.1	Gene:	CG2082 / 40713	FlyBaseID:	FBgn0027608	Length:	368	Species:	Drosophila melanogaster
Sequence 2:	XP_038960545.1	Gene:	Ndrg3 / 296318	RGDID:	1359424	Length:	388	Species:	Rattus norvegicus

Alignment Length:	357	Identity:	100/357 - (28%)
Similarity:	166/357 - (46%)	Gaps:	53/357 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 KYNISTEKCGDLTVIVQGDLSQQEKRAVFITVHDLGCNHNS-FQEFVSSPCMTEIKERSCFIHVD 88
            :::|.|.. |.:.|.::|  ..:..|.|.:|.||:|.||.| |..|.:...|.||.:.....|||
  Rat    32 EHDIETPH-GMVHVTIRG--LPKGNRPVILTYHDIGLNHKSCFNTFFNFEDMQEITQHFAVCHVD 93

  Fly    89 VPGHADNAEALADGFPFPSLQSLGEDLVTVLDYLHVKYVIGLGEGAGANVLARFGLAHPSRVLGL 153
            .||..:.|.:...|:.:|::..|.|.|..||.:|.:|.:||:|.||||.:|:||.|.||..|.||
  Rat    94 APGQQEAAPSFPTGYQYPTMDELAEMLPPVLTHLSMKSIIGIGVGAGAYILSRFALNHPELVEGL 158

  Fly   154 ILINATGSAASVVQSFKNKFISWKSDEVA---QSAESFLMYHKFGHVMEQIVGENPDKEKIVAEY 215
            :|||....|..        :|.|.:.:::   .:....::.|.||   ::.:..|.|   ::..|
  Rat   159 VLINIDPCAKG--------WIDWAASKLSGLTTNVVDIILAHHFG---QEELQANLD---LIQTY 209

  Fly   216 QKRLHRSLNSKNIGLYVKAFMNRKDL------------TLKGCKVDVILITGMLSPYASMVEKLH 268
            :..:.:.:|.:|:.|::.::..|:||            .||..|...:|:.|..||....|.:.:
  Rat   210 RLHIAQDINQENLQLFLGSYNGRRDLEIERPILGQNDNRLKTLKCSTLLVVGDNSPAVEAVVECN 274

  Fly   269 RDVEKERVTILKIERAGDV-LADAPGKVAQSILLFCKGQGLL-------------TSVVMPGVDR 319
            ..::....|:||:...|.: ....|||:.::...|.:|.|.:             .|..|..:.|
  Rat   275 SRLDPINTTLLKMADCGGLPQVVQPGKLTEAFKYFLQGMGYIPYVQLSHLSSESVPSASMTRLAR 339

  Fly   320 GRAFSTASS-GSLEGANGSRRLSRGISMEDYD 350
            .|..||:|| ||     |....||.::....|
  Rat   340 SRTHSTSSSIGS-----GESPFSRSVTSNQSD 366

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2082	NP_001163513.1	Abhydrolase	26..310	CDD:419691	86/313 (27%)
Ndrg3	XP_038960545.1	Ndr	32..317	CDD:397285	86/301 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D359278at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11034
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.020