Protein Alignment Sec8 and exoc4

DIOPT Version :9

• Sequence 1: NP_730996.2
• Gene: Sec8 / 40712
• FlyBaseID: FBgn0266672
• Length: 985
• Species: Drosophila melanogaster
• Sequence 2: XP_004913109.2
• Gene: exoc4 / 100379737
• XenbaseID: XB-GENE-980585
• Length: 1003
• Species: Xenopus tropicalis
• Alignment Length: 1042
• Identity: 336/1042 - (32%)
• Similarity: 558/1042 - (53%)
• Gaps: 143/1042 - (13%)

  Fly    13 VKYGKDESAGCGFLVNVIKSLGFSETTEERQKEKQKIEAEFKRSDLRLNELVSRHDQQLTQVLPL 77
            :...||.|   |.|::||::|..|:..|:|:.||.::|..:::.|..|:|.:.:|..:||..:..
 Frog     8 ISKSKDPS---GLLISVIRTLSTSDDVEDRETEKGRLEEAYEKCDHDLDEKIEQHFTELTTAIRT 69

  Fly    78 FSQVSSEVTASRERIHAVKENLGVCKRLLQCRRDELRKMWMDAVQHKYVLEMLEQIQELRKVPQR 142
            :..::..:|:||.:|..|||||..||.||.|:||||||:|::.::||:||.:|::|:.:::|||:
 Frog    70 YQSITERITSSRNKIKQVKENLLSCKMLLHCKRDELRKLWIEGIEHKHVLNLLDEIENIKQVPQK 134

  Fly   143 VVGYTAKRQYLHASKALTDALTTLNGPLQAVEGLSDLRTDLQTRRQQLYQRLHEELVTQVYTNSA 207
            :....|.:.||.|:..|..|:.:|.|||..||||||||.:|.:::..::..|.:||...:|..|.
 Frog   135 LEQCMASKHYLSATDMLVSAVDSLEGPLLQVEGLSDLRLELHSKKLNMHSVLIDELHRHLYIKST 199

  Fly   208 NEALSSFQRTNSSRLNSSF------------TRGIGARRSTDRIEANARVRKALAEMAQSFDLDK 260
                |...:.|..::.||.            |.....|:..|..........::.|::    |:.
 Frog   200 ----SRVGQWNKDKMRSSLLVKDSPVPLLDVTNLSTPRKFLDGSHFGTPTCSSVKELS----LED 256

  Fly   261 AEVIEDADLIYPELSMSYFVAIIVESFGMLHKVPDSLETLRVQIQTELLNVVRHTTHQLSVSG-- 323
            .:...|:|   ||.:...|:.|:::....|.|:|::::.::.:::.||..:|:.:|.|::.:|
 Frog   257 IKEDPDSD---PEENSKIFMGILIKGLAKLKKIPETVKAIKERLEQELKQIVKRSTTQVADNGYQ 318

  Fly   324 ----ATADTNP--LLSLLEVIFKQFKAIAKTHSLLLKNYLSVGQKYSVVGP--------QPYDLT 374
                .|.:..|  ||.|||::|.:|.|:|..||::|.:.     :.:|:.|        :.||:.
 Frog   319 RGENNTQENQPRLLLELLELLFDKFNAVATAHSVVLGHL-----QQTVLSPTSQHDGDIKLYDMP 378

  Fly   375 DFWAQAQSVLQLLLTDYLDIQN--AAADESAQTGFSEPTSNINSYFLRRKVPSTKRSMFKFDKSS 437
            :.|.:.|:|||:|||:|||::|  |:::.|.|..::.......::|.::|....|.|:|||:.||
 Frog   379 EVWVKIQTVLQILLTEYLDMKNTKASSEASTQLSYASTGREFAAFFAKKKPQRPKNSLFKFESSS 443

  Fly   438 HVGTSNNSDAFKEHRRNASDAS------VDDNLAGQLGGSGKGSTSGLFPHEKKQREKILICTPD 496
            |  ..:.|...:|.||.....|      .||||.|  ||:.                  .:|.|.
 Frog   444 H--AISMSAYLREQRRELYSKSGELQGGPDDNLIG--GGTR------------------FVCKPG 486

  Fly   497 QSIITKVYLPLMG-----------------------------------YIKEIENFMKCKPGQPC 526
            ...||.::.||:.                                   :|:|||:.|...|.:.|
 Frog   487 ARNITIIFHPLLSMNLLANAQLEGAGNLVGVLAVRPEASTTEQKMAPRFIQEIEHAMGLGPAKQC 551

  Fly   527 SLHDFLDNYIKDTFLTKGHN--RNLQLTIESLSKNQDAWRTIISPEEIKALNLSRPLLQSTVMVE 589
            .|.:||..|||:.||   |.  ..:...||.::|..|..:.:.|.:.:|.|.:.||||||||:||
 Frog   552 PLREFLTMYIKNIFL---HQVLAEINKEIEGVTKVSDPLKILASADTMKTLGVQRPLLQSTVIVE 613

  Fly   590 RRLMETKNLIQDLPCYSEDLLKMVCALLKAYREICQAAYRGIVQPDSEDKRIYSVAWLKDEDISR 654
            :.:.:..||::||..||:..|.|||..|:.|::.|.||:|.:||  ||:|.:.|.:|.||:||:|
 Frog   614 KTVQDLMNLMRDLSAYSDQFLNMVCVKLQEYKDTCSAAFRTVVQ--SEEKMVISASWAKDDDITR 676

  Fly   655 FLKTLPNWTDLKTYSQKSRHNRKLHRGSFEPSEEESPLQVQQRNIREAEMLTSNLGEGGITQQEI 719
            .||:||||.::....|            ..|..||....|:....:|:|:|..|||:..|.|.||
 Frog   677 LLKSLPNWLNMAQPKQ------------LRPKREEEEDFVRAAFAKESEVLIGNLGDKLIPQAEI 729

  Fly   720 LVEISVLKELAILQESMEWFSCR----VSEFANDLRRPLVNGLNAVPAECGADI-AVKDGTIKVM 779
            :.::|.||.||.|.||:||.:.|    ::.|.:.  :.:..|.:::   ...|| .|.:..::.:
 Frog   730 MGDVSDLKALANLHESLEWLAGRLKAAIASFPSS--QTMSPGSDSI---ASVDIPVVSELILQTL 789

  Fly   780 TNLALEFDELANTCLLVLHLEVRVQCFHYLRSKSSVRTNSYVGSKDDILEPDRQVQVLTKRLSEM 844
            :.||..|.::::.|||||||||||.|||||...:. :.|..:.:..:.::.|..:..|.|.:|.:
 Frog   790 SELAKSFQDMSDRCLLVLHLEVRVHCFHYLIPLAK-QGNYAIVANVESMDYDPLIVRLNKDISGI 853

  Fly   845 DEAFSATLHPRKTRYIFEGLAHLASRILIQASNYLEHIDQITVQRMCRNAIALQQTLSNITASRE 909
            :||..|:|...|.:||||||.||.|.|||..:.|.:.|.:..:::||||...|||.|:|||.|||
 Frog   854 EEAMGASLQQHKFQYIFEGLGHLISCILINGAQYFKRISESGIKKMCRNIFVLQQNLTNITMSRE 918

  Fly   910 VALDQARHFYELLCMEPDEILNALLERGTQFSEMQLLNALQLSCKS-FGITDANLLASYQQKLSD 973
            ..||.||.:||::....||:||.::::|.:::|::.:|||.|..:| .|:.|........|:|.:
 Frog   919 ADLDFARQYYEMMYNTADELLNLVVDQGVKYTELEYINALSLLHRSQTGVGDQTTQNMRLQRLKE 983

  Fly   974 IL 975
            |:
 Frog   984 II 985

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sec8	NP_730996.2	Sec8_exocyst	<32..143	CDD:281972	43/110 (39%)
		L27	156..207	CDD:280918	19/50 (38%)
exoc4	XP_004913109.2	Sec8_exocyst	<51..137	CDD:367782	35/85 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	382	1.000	Domainoid score	I827
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H40654
Inparanoid	1	1.050	517	1.000	Inparanoid score	I1261
OMA	1	1.010	-	-		QHG55678
OrthoDB	1	1.010	-	-		D334342at33208
OrthoFinder	1	1.000	-	-		FOG0004885
OrthoInspector	1	1.000	-	-		oto103774
Panther	1	1.100	-	-	LDO	PTHR14146
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X5225
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	11.080