DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2091 and Dcps

DIOPT Version :9

Sequence 1:	NP_649582.1	Gene:	CG2091 / 40711	FlyBaseID:	FBgn0037372	Length:	374	Species:	Drosophila melanogaster
Sequence 2:	XP_038936851.1	Gene:	Dcps / 266605	RGDID:	628887	Length:	342	Species:	Rattus norvegicus

Alignment Length:	318	Identity:	131/318 - (41%)
Similarity:	193/318 - (60%)	Gaps:	25/318 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 STEVKSPSYDLSKFQLKRILTNNSVRKSISLLGTF----PDLGTDDAIVVFEKNAYRESDVATAS 67
            |..|:.|   .|.|:::::|..::..|.|.|.|..    .|...:||:|:.||..::...||
  Rat    35 SAPVRLP---FSGFRVQKVLRESARDKIIFLHGKVNEDSGDTHGEDAVVILEKTPFQVEHVA--- 93

  Fly    68 SEESPKKPSYFTADLKVDTEFINNIYGSFQVVPTQ---DLC----SVKSTVIYPATEKHIEKYSV 125
                    ...|.:.::..:|.|:||.::.:.|.:   |.|    .:|:||:|||||||::||..
  Rat    94 --------QLLTGNPELKLQFSNDIYSTYNLFPPRHLSDFCCIIVDIKTTVVYPATEKHLQKYMR 150

  Fly   126 SQKYLIRETPDLYQRITLPYLTSSQFSLEWVYNILEHKQETERIVYEDRDPKTGFILLPDLKWDG 190
            ....|||||.|.|:.:|||||.|...|::||||||:.|.|.:|||:|:.||..||:|:|||||:.
  Rat   151 QDLRLIRETGDDYRSLTLPYLESQSLSIQWVYNILDKKAEADRIVFENPDPSDGFVLIPDLKWNQ 215

  Fly   191 RNVETLYLLGIVHKRDIKSLRDLNESHLDLLRNVRQASKDAIAKLYGINPNQLRMYFHYQPSFYH 255
            :.::.|||:.|.|:|.|:|||||...||.||||:.:..::||.|.|.:..::||:|.||.||:||
  Rat   216 QQLDDLYLIAICHRRGIRSLRDLTPEHLPLLRNILREGQEAILKRYQVTGDRLRVYLHYLPSYYH 280

  Fly   256 LHVHINPVRNDAPGIWCEKSHMLDTVINNLELMPDYYQRATLPFVLYEGNKLLDLYEQ 313
            ||||...:..:|||...|::|:|..||.|||..|.:|||.||.|.|...:.||.|.::
  Rat   281 LHVHFTALGFEAPGSGVERAHLLAEVIENLECDPKHYQRRTLTFALRTDDPLLQLLQK 338

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2091	NP_649582.1	DcpS	15..124	CDD:283339	34/119 (29%)
		COG5075	17..307	CDD:227407	125/300 (42%)
		DcpS_C	155..260	CDD:288796	56/104 (54%)
Dcps	XP_038936851.1	COG5075	45..326	CDD:227407	123/291 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352673
Domainoid	1	1.000	139	1.000	Domainoid score	I4686
eggNOG	1	0.900	-	-		E1_COG5075
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H32202
Inparanoid	1	1.050	249	1.000	Inparanoid score	I3161
OMA	1	1.010	-	-		QHG58249
OrthoDB	1	1.010	-	-		D416175at33208
OrthoFinder	1	1.000	-	-		FOG0005125
OrthoInspector	1	1.000	-	-		oto97102
orthoMCL	1	0.900	-	-		OOG6_104575
Panther	1	1.100	-	-	LDO	PTHR12978
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3646
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770