Protein Alignment Madm and WNK4

DIOPT Version :9

• Sequence 1: NP_001303420.1
• Gene: Madm / 40710
• FlyBaseID: FBgn0027497
• Length: 637
• Species: Drosophila melanogaster
• Sequence 2: NP_200643.1
• Gene: WNK4 / 835947
• AraportID: AT5G58350
• Length: 571
• Species: Arabidopsis thaliana
• Alignment Length: 590
• Identity: 132/590 - (22%)
• Similarity: 219/590 - (37%)
• Gaps: 183/590 - (31%)

  Fly    94 SEILEESPCGRWLKRREEVDQRDVPGIDCVHLAMDTEEGVEVVWNEVQYASLQELKSQEEKMRQV 158
            :|.:|..|.||: .|..|:..|.  .:..|:.|:|.:.|:||.|::|:   |:|:......::::
plant     7 AEYVETDPTGRY-GRFAEILGRG--AMKTVYKAIDEKLGIEVAWSQVK---LKEVLRSSVDLQRL 65

  Fly   159 FDN---LLQLDHQNIVKFHRYWTDTQQAERPRVVFITEYMSSGSLKQFLKRTKRNAKRLPLESWR 220
            :..   |..|:|::|::|:..|.|   .....:.||||..:||:|:|:    |....|:.:.:.:
plant    66 YSEVHLLSTLNHKSIIRFYTSWID---VHNHTLNFITELFTSGTLRQY----KNKYLRIDIRAIK 123

  Fly   221 RWCTQILSALSYLHSCSPPIIHGNLTCDSIFIQ-HNGLVKIGSVVPDAVHYSVRRGRERERERER 284
            .|..|||..|.|||...||:||.:|.||:||:. |.|.||||.:           |..|......
plant   124 SWARQILEGLVYLHEHDPPVIHRDLKCDNIFVNGHLGQVKIGDL-----------GLARMLRDCH 177

  Fly   285 GAH------YFQAPEYGAADQLTAALDIYAFGMCALEMAALEIQPSNSESTA-INEETIQRTI-- 340
            .||      .|.|||. ..:.....:|:|:||||.|||...|...|.....| |.::.:...:
plant   178 SAHSIIGTPEFMAPEL-YEENYNELIDVYSFGMCFLEMITSEFPYSECNHPAQIYKKVVGGKLPG 241

  Fly   341 -FSLENDLQ-RDLIRKCLNPQPQDRPSANDLLFHPLLFEVHSLKLLTAHCLVFSPANRTMFSETA 403
             |....|:: :..|.||| .....|.||.:||..|.|....|..:.|
plant   242 AFYRVGDIEAQRFIGKCL-VSASKRVSAKELLQDPFLASDESWMVYT------------------ 287

  Fly   404 FDGLMQRYYQPDVVMAQLRLAGGQERQYRLADVSGADKLEKFVEDVKYGVYPLITYSGKKPPNFR 468
                                             |||...:.|:.:
plant   288 ---------------------------------SGAGNPKPFLNE-------------------- 299

  Fly   469 SRAASPERADSVKSATPEPVDTESRRIVNMMCSVKIKEDSNDITMTILLRMDDKMNRQLTCQVN- 532
                  ...|::|..     |.|.|  ..|..:.|:..:.|.|.:.:.:..|:.:...:....:
plant   300 ------NEMDTLKLE-----DDELR--TEMSIAGKLGAEDNKIDLEVQIAYDNGLANNVFFPFDI 351

  Fly   533 ENDTAADLTSELVRLGFVHLDDQDKIQVLLEETLKAGVMSDGAGAESSGAGVTTTATMAALEQLE 597
            .|||:.|:..|:|:          :::::..|.::...|.||                 |:..|.
plant   352 MNDTSIDVAKEMVK----------ELEIIDWEPVEIAKMIDG-----------------AISSLV 389

  Fly   598 RNWSISSD----------------------ADKQGTAVMYVPQEQQN-ADGDVDVE-------HS 632
            .:|....|                      :..|.:...|:.:..|: ...|:..|       ||
plant   390 SDWKYEEDDETPHDHHRHRTDSFHSSSSHASSSQASLSNYMARGLQDWVQDDLHDETYSQSSSHS 454

  Fly   633 GTTSN 637
            |:.||
plant   455 GSYSN 459

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Madm	NP_001303420.1	PK_NRBP1_like	114..376	CDD:270886	84/276 (30%)
		S_TKc	123..375	CDD:214567	83/266 (31%)
WNK4	NP_200643.1	STKc_WNK	17..277	CDD:270885	87/285 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D695382at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR13902
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X143
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.020