Protein Alignment Madm and WNK9

DIOPT Version :10

• Sequence 1: NP_649581.1
• Gene: Madm / 40710
• FlyBaseID: FBgn0027497
• Length: 637
• Species: Drosophila melanogaster
• Sequence 2: NP_001031960.1
• Gene: WNK9 / 832881
• AraportID: AT5G28080
• Length: 492
• Species: Arabidopsis thaliana
• Alignment Length: 564
• Identity: 138/564 - (24%)
• Similarity: 221/564 - (39%)
• Gaps: 136/564 - (24%)

  Fly    92 DESEILEESPCGRWLKRREEVDQRDVPGIDCVHLAMDTEEGVEVVWNEVQYASLQELKSQEEKMR 156
            |.||.:|..|.||:.:..|.:.:   .....|:...|..:|:||.||:|:.....:...:.|::.
plant    11 DYSEYVEVDPTGRYGRYNEVLGK---GSSKTVYRGFDEYQGIEVAWNQVKLYDFLQSPQELERLY 72

  Fly   157 QVFDNLLQLDHQNIVKFHRYWTDTQQAERPRVVFITEYMSSGSLKQFLKRTKRNAKRLPLESWRR 221
            .....|..|.|::|:||:..|.||   :...:.|:||..:||:|:|:  |.|.  ||:.:.:.:.
plant    73 CEIHLLKTLKHKSIMKFYASWVDT---DNRNINFVTEMFTSGTLRQY--RLKH--KRVNIRAVKN 130

  Fly   222 WCTQILSALSYLHSCSPPIIHGNLTCDSIFIQHN-GLVKIGSVVPDAVHYSVRRGRERERERERG 285
            ||.|||..|:|||:..||:||.:|.||:|||..| |.||||.:           |.....:....
plant   131 WCRQILRGLNYLHTHDPPVIHRDLKCDNIFINGNQGEVKIGDL-----------GLAACLQHSHA 184

  Fly   286 AHYFQAPEYGA----ADQLTAALDIYAFGMCALEMAALEIQPSNSESTAINEETIQRTIFS---- 342
            ||....||:.|    .::....:|||:||||.|||...:...|.....|    .|.:.:.|
plant   185 AHCVGTPEFMAPEVYKEEYNQLVDIYSFGMCVLEMVTFDYPYSECSHPA----QIYKRVISGKKP 245

  Fly   343 -----LENDLQRDLIRKCLNPQPQDRPSANDLLFHPLLFEVHSLKLLTAHCLVFSPANRTMFSET 402
                 :::...|..|.|||               ..:...:.:.:||..|.|....::
plant   246 DGLDKVKDPEVRGFIEKCL---------------ATVSLRLSACELLDDHFLCIDESD------- 288

  Fly   403 AFDGLMQRYYQPDVVMAQLRLAGGQERQYRLADVSGADKLEKF-VEDVKYGVYPLIT-----YSG 461
                 |:|.                |.:..|.|.:|......: :.....|.|.|..     |:|
plant   289 -----MRRV----------------ESEKGLIDEAGTPLRHSYHIPHYSNGYYSLYNQNQWDYNG 332

  Fly   462 KKPPNFRSRAASPERADSVKSATPEPVDTESRRIVNMMCSVKIKEDSNDITMTILLRMDDKMNRQ 526
                   .........|.::....:..:.|.:|..::..|:|.|...|...:.:.|:..:|..
plant   333 -------DETVESHEIDLLEFQNDDDEEEEDKRFGSVDISIKGKRRDNGDGLFLRLKTVNKEG-- 388

  Fly   527 LTCQVN-------ENDTAADLTSELVRLGFVHLDDQDKIQVLLEETLKAGVMSDGAGAESSGAGV 584
              |..|       |.|||..:..|:|.  .:.:||:|        ..|...|.||
plant   389 --CVRNIYFPFDIETDTAISVAREMVE--ELEMDDRD--------VTKIANMIDG---------- 431

  Fly   585 TTTATMAALEQLERNWSI--SSDADKQGT-AVMYVPQEQQNADG 625
                   .:..|..||||  ||::::... :||...:.|...||
plant   432 -------EIASLVPNWSIFCSSESNRSSVGSVMDFNEMQCGRDG 468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Madm	NP_649581.1	PK_NRBP1_like	114..376	CDD:270886	79/275 (29%)
WNK9	NP_001031960.1	STKc_WNK	23..282	CDD:270885	84/298 (28%)
		OSR1_C	367..434	CDD:463491	20/97 (21%)