Protein Alignment Madm and nrbp1

DIOPT Version :9

• Sequence 1: NP_001303420.1
• Gene: Madm / 40710
• FlyBaseID: FBgn0027497
• Length: 637
• Species: Drosophila melanogaster
• Sequence 2: NP_001005659.1
• Gene: nrbp1 / 448149
• XenbaseID: XB-GENE-5916003
• Length: 526
• Species: Xenopus tropicalis
• Alignment Length: 562
• Identity: 273/562 - (48%)
• Similarity: 363/562 - (64%)
• Gaps: 58/562 - (10%)

  Fly     4 SQANAGISGSTVADEPIQHHPSLAAGPVSASCPAATPPSQSTQQPPPHIVSASTADAGSSAAVGV 68
            |:.....:.||.:|      |.:.:| ||.|.|.:.||:      ||.
 Frog     2 SEGEGKTAPSTGSD------PKMESG-VSMSPPVSAPPA------PPQ----------------- 36

  Fly    69 GVVAGSEGVNLDSSPRESGDDSEDESEILEESPCGRWLKRREEVDQRDVPGIDCVHLAMDTEEGV 133
                           .|..::||||||||||||||||.||||||:||:|||||..:|||||||||
 Frog    37 ---------------EEEEEESEDESEILEESPCGRWQKRREEVNQRNVPGIDSAYLAMDTEEGV 86

  Fly   134 EVVWNEVQYASLQELKSQEEKMRQVFDNLLQLDHQNIVKFHRYWTDTQQAERPRVVFITEYMSSG 198
            ||||||||::..:..|.||||::.|||||:||:|.||||||:||.|.:: .|.||:|||||||||
 Frog    87 EVVWNEVQFSERKNFKMQEEKVKAVFDNLIQLEHLNIVKFHKYWADVKE-NRARVIFITEYMSSG 150

  Fly   199 SLKQFLKRTKRNAKRLPLESWRRWCTQILSALSYLHSCSPPIIHGNLTCDSIFIQHNGLVKIGSV 263
            |||||||:||:|.|.:..::|:||||||||||||||||.|||||||||||:||||||||:|||||
 Frog   151 SLKQFLKKTKKNHKTMNEKAWKRWCTQILSALSYLHSCDPPIIHGNLTCDTIFIQHNGLIKIGSV 215

  Fly   264 VPDAVHYSVRRGRERERERERGAHYFQAPEYGAADQLTAALDIYAFGMCALEMAALEIQPSNSES 328
            .||.::..|:..    ||.::..|:| |||||....:|.|:|||:|||||||||.|||| .|.||
 Frog   216 APDTINNHVKTC----REEQKNLHFF-APEYGEVTNVTTAVDIYSFGMCALEMAVLEIQ-GNGES 274

  Fly   329 TAINEETIQRTIFSLENDLQRDLIRKCLNPQPQDRPSANDLLFHPLLFEVHSLKLLTAHCLVFSP 393
            :.:.:|.|...|..||:.|||:.|:|||...|..||:|.:|||||.||||.|||||.|||:|
 Frog   275 SYVPQEAINNAIQFLEDPLQREFIQKCLETDPSKRPTARELLFHPALFEVPSLKLLAAHCIV--- 336

  Fly   394 ANRTMFSETAFDGLMQRYYQPDVVMAQLRLAGGQERQYRLADVSGADKLEKFVEDVKYGVYPLIT 458
            .::.|..|.|.:. |.:......|:|::..| .:|....:...|.|.:|:||:|||:.|:|||..
 Frog   337 GHQHMIPENALEE-MTKNLDMSAVLAEISHA-DREGVRMIFSQSPALELDKFLEDVRNGIYPLTA 399

  Fly   459 YSGKKPPNFRSRAA-SPERADSVKSATPEPVDTESRRIVNMMCSVKIKEDSNDITMTILLRMDDK 522
            :...:|...:.... ||....|||:.||||.:.|:|::|.|.|:::..::.....:|:||:::||
 Frog   400 FGVPRPQQPQQEVVKSPVVPPSVKTPTPEPAEVETRKVVQMQCNIESVDEGAKHHLTLLLKLEDK 464

  Fly   523 MNRQLTCQVNENDTAADLTSELVRLGFVHLDDQDKIQVLLEE 564
            :||.|:|.:..|:...:|.:|||:||||...||.::..||||
 Frog   465 LNRHLSCDLLPNENIQELAAELVQLGFVSESDQIRLACLLEE 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Madm	NP_001303420.1	PK_NRBP1_like	114..376	CDD:270886	164/261 (63%)
		S_TKc	123..375	CDD:214567	157/251 (63%)
nrbp1	NP_001005659.1	PK_NRBP1	52..328	CDD:270936	182/282 (65%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	277	1.000	Domainoid score	I1695
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H8373
Inparanoid	1	1.050	475	1.000	Inparanoid score	I1453
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D233882at33208
OrthoFinder	1	1.000	-	-		FOG0002915
OrthoInspector	1	1.000	-	-		oto102876
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X143
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.060