Protein Alignment Madm and puf60

DIOPT Version :10

• Sequence 1: NP_649581.1
• Gene: Madm / 40710
• FlyBaseID: FBgn0027497
• Length: 637
• Species: Drosophila melanogaster
• Sequence 2: XP_031759079.1
• Gene: puf60 / 100145091
• XenbaseID: XB-GENE-5785623
• Length: 529
• Species: Xenopus tropicalis
• Alignment Length: 585
• Identity: 105/585 - (17%)
• Similarity: 189/585 - (32%)
• Gaps: 177/585 - (30%)

  Fly   129 TEEGVEVVWNEVQYASLQELKSQEEKMRQVFDNLLQLDHQNIVKFHRYWTDTQQAERPRVVFITE 193
            |.|..|.:....:||..|.:||             .|..|.|...|:..|:.|.|.      :|
 Frog    30 TLEQQEALQKAKKYAMEQSIKS-------------VLVKQTIAHQHQQLTNLQMAA------VT- 74

  Fly   194 YMSSGS-LKQFLKRTKRNAKRLPLESWRRWCTQILSALSY-------LHSCSP--PIIHGNLTCD 248
             ||.|. |........:..:.|.:     .|...:.::.|       ..:.:|  ||...:::.|
 Frog    75 -MSFGDPLSPLQSMAAQRQRALAI-----MCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWD 133

  Fly   249 SIFIQHNGLVKIGSVVPDAVHYSVRR-------GRE-------------------RERERERGAH 287
            |:.::|.|...:...||:|...::.:       ||.                   .|..|.....
 Frog   134 SVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARSFNRI 198

  Fly   288 YFQAPEYGAADQLTAALDI----YAFGMCALEMAA-------------LEIQPSNSESTAINEET 335
            |..:.....:|:     ||    .|||.....|.|             :|.:...|...|::
 Frog   199 YVASVHQDLSDE-----DIKSVFEAFGKIKSCMLARDPTTGKHKGYGFIEYEKGQSSQDAVS--- 255

  Fly   336 IQRTIFSLENDLQRDLIRKCLNPQPQDRPSANDLLFHPLLFEVHSLKLLTAHCLVFSPANRTMFS 400
             ...:|.|.....|  :.|.:.| |.           |||.......|..|..:..:.|...:.:
 Frog   256 -SMNLFDLGGQYLR--VGKAVTP-PM-----------PLLTPATPGGLPPAAAVAAAAATAKITA 305

  Fly   401 ETAFDG--LMQRYYQPDVVMAQLRLA---GGQERQYRLADVSGADKLEKFVEDVKYGVYP----- 455
            :.|..|  ::.....|.:|...|.||   |...:....|...|          |..||.|
 Frog   306 QEAVAGAAVLGTLASPGLVTPALTLAQPLGALPQAVMAAQAPG----------VITGVTPVRPPL 360

  Fly   456 --------LITYSGKKPPNFRSRAASPERADS---VKSATPEPVDTESRRIVN-------MMCSV 502
                    |:......||.........|:.:.   .:|..||.:..:....::       :|..:
 Frog   361 PVTIPPVGLVNPLLSSPPTLAQLEVKKEKEEEEILPESERPEMLSEQEHMSISGSSARHMVMQKL 425

  Fly   503 KIKEDSNDITMTILLRMDDKMNRQLTCQVNENDTAADLTSELVRLGFVH--------LDDQDKIQ 559
            ..|::|   |:.:|..|.|.  |.:     ::|...::|.|..:.|.|:        ..:::..:
 Frog   426 MRKQES---TVMVLRNMVDP--RDI-----DDDLEGEVTEECGKFGAVNRVIIYQEKQGEEEDAE 480

  Fly   560 VLLEETLKAGVMSDGAGAESSGAGVTTTATMAALEQLERNWSISSDADKQGTAVMYVPQEQQNAD 624
            ::::..::..:.|:               |..|::.|...|.    |.::..|.:|..:...|:|
 Frog   481 IIVKIFVEFSMSSE---------------TQKAIQALNGRWF----AGRKVVAEVYDQERFDNSD 526

  Fly   625  624
             Frog   527  526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Madm	NP_649581.1	PK_NRBP1_like	114..376	CDD:270886	57/299 (19%)
puf60	XP_031759079.1	half-pint	10..529	CDD:130706	105/585 (18%)