Protein Alignment CG1236 and Ctbp2

DIOPT Version :10

• Sequence 1: NP_649579.2
• Gene: CG1236 / 40708
• FlyBaseID: FBgn0037370
• Length: 347
• Species: Drosophila melanogaster
• Sequence 2: NP_445787.1
• Gene: Ctbp2 / 81717
• RGDID: 68372
• Length: 988
• Species: Rattus norvegicus
• Alignment Length: 330
• Identity: 86/330 - (26%)
• Similarity: 138/330 - (41%)
• Gaps: 60/330 - (18%)

  Fly    58 PVPRSELIRVVAGKD-------------ALYC--ALTDKVDKEVL-DAAGPQ------------- 93
            |:....|:.::.|:|             ..:|  ..|.::.::|| :|.|..
  Rat   572 PLHPRPLVALLDGRDCTVEMPILKDLATVAFCDAQSTQEIHEKVLNEAVGAMMYHTITLTREDLE 636

  Fly    94 ----LKCVATISVGYDHIDVEECRKRGIRVGFTPDVLTDATAELTLALLLATNRR---LFEA--- 148
                |:.:..|..|||::|::...:.||.|...|....:.||:.|:..:|...||   |::|
  Rat   637 KFKALRVIVRIGSGYDNVDIKAAGELGIAVCNIPSAAVEETADSTVCHILNLYRRNTWLYQALRE 701

  Fly   149 ---------NKQVYNGGWKSWAPMWMCGQGLKGSRVGLLGFGRIGQEIAARIVPFKPTEITYTTR 204
                     .::|.:|..:           ::|..:||:||||.||.:|.|...|..:.|.|...
  Rat   702 GTRVQSVEQIREVASGAAR-----------IRGETLGLIGFGRTGQAVAVRAKAFGFSVIFYDPY 755

  Fly   205 SLRPKEAAAVNARHVDFDEMLRESDLIVVCCALTPETKEIFNATAFQKMKPNCILINTARGGVVD 269
            .....|.:....|.....::|.:||.:.:.|.|......:.|....::|:....|:|.||||:||
  Rat   756 LQDGIERSLGVQRVYTLQDLLYQSDCVSLHCNLNEHNHHLINDFTIKQMRQGAFLVNAARGGLVD 820

  Fly   270 QKALYEALKTKRILAAGLDVTTPEPLPI-DDPLLKLDNVVILPHIGSADIETRKEMSRITARNIL 333
            :|||.:|||..||..|.|||...||... ..||....|::..||......:...||....|..|.
  Rat   821 EKALAQALKEGRIRGAALDVHESEPFSFAQGPLKDAPNLICTPHTAWYSEQASLEMREAAATEIR 885

  Fly   334 AALAG 338
            .|:.|
  Rat   886 RAITG 890

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1236	NP_649579.2	GDH	27..338	CDD:240626	85/328 (26%)
Ctbp2	NP_445787.1	PHA03247	<353..577	CDD:223021	1/4 (25%)
		CtBP_dh	577..895	CDD:240624	85/325 (26%)