DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1236 and Grhpr

DIOPT Version :9

Sequence 1:	NP_649579.2	Gene:	CG1236 / 40708	FlyBaseID:	FBgn0037370	Length:	347	Species:	Drosophila melanogaster
Sequence 2:	NP_001107226.1	Gene:	Grhpr / 680021	RGDID:	1308851	Length:	335	Species:	Rattus norvegicus

Alignment Length:	322	Identity:	170/322 - (52%)
Similarity:	222/322 - (68%)	Gaps:	3/322 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 KVYVTRPDVDDSGLELLRKS--CQVSTWHETNPVPRSELIRVVAGKDALYCALTDKVDKEVLDAA 90
            ||:||.| :...|...|.::  |:|..|:..:|:|..:|.:.|||...|.|.|:|:|||::||||
  Rat    15 KVFVTGP-LPAQGRAALAQATDCEVEQWNSDDPIPSKDLEQGVAGAYGLLCRLSDRVDKKLLDAA 78

  Fly    91 GPQLKCVATISVGYDHIDVEECRKRGIRVGFTPDVLTDATAELTLALLLATNRRLFEANKQVYNG 155
            |..|:.::|:|||.||:.::|.:|||||||:||.|||||||||.::|||.|.|||.||.::|.||
  Rat    79 GANLRVISTLSVGVDHLALDEIKKRGIRVGYTPGVLTDATAELAVSLLLTTCRRLPEAIEEVKNG 143

  Fly   156 GWKSWAPMWMCGQGLKGSRVGLLGFGRIGQEIAARIVPFKPTEITYTTRSLRPKEAAAVNARHVD 220
            ||.||:|:||||.||..|.||::|.|||||.||.|:.||......||.|..||:|||...|..|.
  Rat   144 GWSSWSPLWMCGYGLSESTVGIVGLGRIGQAIARRLKPFGVQRFLYTGRQPRPQEAAEFQAEFVP 208

  Fly   221 FDEMLRESDLIVVCCALTPETKEIFNATAFQKMKPNCILINTARGGVVDQKALYEALKTKRILAA 285
            ..::..|||.|||.|:|||.|:.:.|...|||||...:.||.:||.||:|:.||:||.:.:|.||
  Rat   209 IAQLAAESDFIVVSCSLTPATRGLCNKDFFQKMKNTAVFINISRGDVVNQEDLYQALASGQIAAA 273

  Fly   286 GLDVTTPEPLPIDDPLLKLDNVVILPHIGSADIETRKEMSRITARNILAALAGDKMVAEVEL 347
            |||||||||||...|||.|.|.|||||||||..:||..||.:.|.|:||.|.|:.|.:|::|
  Rat   274 GLDVTTPEPLPPSHPLLTLKNCVILPHIGSATYKTRNTMSLLAANNLLAGLRGEPMPSELKL 335

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1236	NP_649579.2	GDH	27..338	CDD:240626	166/311 (53%)
CG1236	NP_649579.2	LdhA	27..338	CDD:223980	166/311 (53%)
Grhpr	NP_001107226.1	GDH	14..326	CDD:240626	166/311 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166334937
Domainoid	1	1.000	322	1.000	Domainoid score	I1185
eggNOG	1	0.900	-	-		E1_COG1052
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H49088
Inparanoid	1	1.050	326	1.000	Inparanoid score	I2392
OMA	1	1.010	-	-		QHG53501
OrthoDB	1	1.010	-	-		D1378766at2759
OrthoFinder	1	1.000	-	-		FOG0000836
OrthoInspector	1	1.000	-	-		oto98251
orthoMCL	1	0.900	-	-		OOG6_100397
Panther	1	1.100	-	-	LDO	PTHR10996
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X646
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.810