Protein Alignment CG1236 and CTBP2

DIOPT Version :9

• Sequence 1: NP_649579.2
• Gene: CG1236 / 40708
• FlyBaseID: FBgn0037370
• Length: 347
• Species: Drosophila melanogaster
• Sequence 2: NP_073713.2
• Gene: CTBP2 / 1488
• HGNCID: 2495
• Length: 985
• Species: Homo sapiens
• Alignment Length: 330
• Identity: 86/330 - (26%)
• Similarity: 138/330 - (41%)
• Gaps: 60/330 - (18%)

  Fly    58 PVPRSELIRVVAGKD-------------ALYC--ALTDKVDKEVL-DAAGPQ------------- 93
            |:....|:.::.|:|             ..:|  ..|.::.::|| :|.|..
Human   569 PLHPRPLVALLDGRDCTVEMPILKDLATVAFCDAQSTQEIHEKVLNEAVGAMMYHTITLTREDLE 633

  Fly    94 ----LKCVATISVGYDHIDVEECRKRGIRVGFTPDVLTDATAELTLALLLATNRR---LFEA--- 148
                |:.:..|..|||::|::...:.||.|...|....:.||:.|:..:|...||   |::|
Human   634 KFKALRVIVRIGSGYDNVDIKAAGELGIAVCNIPSAAVEETADSTICHILNLYRRNTWLYQALRE 698

  Fly   149 ---------NKQVYNGGWKSWAPMWMCGQGLKGSRVGLLGFGRIGQEIAARIVPFKPTEITYTTR 204
                     .::|.:|..:           ::|..:||:||||.||.:|.|...|..:.|.|...
Human   699 GTRVQSVEQIREVASGAAR-----------IRGETLGLIGFGRTGQAVAVRAKAFGFSVIFYDPY 752

  Fly   205 SLRPKEAAAVNARHVDFDEMLRESDLIVVCCALTPETKEIFNATAFQKMKPNCILINTARGGVVD 269
            .....|.:....|.....::|.:||.:.:.|.|......:.|....::|:....|:|.||||:||
Human   753 LQDGIERSLGVQRVYTLQDLLYQSDCVSLHCNLNEHNHHLINDFTIKQMRQGAFLVNAARGGLVD 817

  Fly   270 QKALYEALKTKRILAAGLDVTTPEPLPI-DDPLLKLDNVVILPHIGSADIETRKEMSRITARNIL 333
            :|||.:|||..||..|.|||...||... ..||....|::..||......:...||....|..|.
Human   818 EKALAQALKEGRIRGAALDVHESEPFSFAQGPLKDAPNLICTPHTAWYSEQASLEMREAAATEIR 882

  Fly   334 AALAG 338
            .|:.|
Human   883 RAITG 887

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1236	NP_649579.2	GDH	27..338	CDD:240626	85/328 (26%)
		LdhA	27..338	CDD:223980	85/328 (26%)
CTBP2	NP_073713.2	CtBP_dh	574..892	CDD:240624	85/325 (26%)
		SerA	590..900	CDD:223189	82/309 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165141272
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840