Protein Alignment CG1236 and CTBP2

DIOPT Version :10

• Sequence 1: NP_649579.2
• Gene: CG1236 / 40708
• FlyBaseID: FBgn0037370
• Length: 347
• Species: Drosophila melanogaster
• Sequence 2: NP_073713.2
• Gene: CTBP2 / 1488
• HGNCID: 2495
• Length: 985
• Species: Homo sapiens
• Alignment Length: 330
• Identity: 86/330 - (26%)
• Similarity: 138/330 - (41%)
• Gaps: 60/330 - (18%)

  Fly    58 PVPRSELIRVVAGKD-------------ALYC--ALTDKVDKEVL-DAAGPQ------------- 93
            |:....|:.::.|:|             ..:|  ..|.::.::|| :|.|..
Human   569 PLHPRPLVALLDGRDCTVEMPILKDLATVAFCDAQSTQEIHEKVLNEAVGAMMYHTITLTREDLE 633

  Fly    94 ----LKCVATISVGYDHIDVEECRKRGIRVGFTPDVLTDATAELTLALLLATNRR---LFEA--- 148
                |:.:..|..|||::|::...:.||.|...|....:.||:.|:..:|...||   |::|
Human   634 KFKALRVIVRIGSGYDNVDIKAAGELGIAVCNIPSAAVEETADSTICHILNLYRRNTWLYQALRE 698

  Fly   149 ---------NKQVYNGGWKSWAPMWMCGQGLKGSRVGLLGFGRIGQEIAARIVPFKPTEITYTTR 204
                     .::|.:|..:           ::|..:||:||||.||.:|.|...|..:.|.|...
Human   699 GTRVQSVEQIREVASGAAR-----------IRGETLGLIGFGRTGQAVAVRAKAFGFSVIFYDPY 752

  Fly   205 SLRPKEAAAVNARHVDFDEMLRESDLIVVCCALTPETKEIFNATAFQKMKPNCILINTARGGVVD 269
            .....|.:....|.....::|.:||.:.:.|.|......:.|....::|:....|:|.||||:||
Human   753 LQDGIERSLGVQRVYTLQDLLYQSDCVSLHCNLNEHNHHLINDFTIKQMRQGAFLVNAARGGLVD 817

  Fly   270 QKALYEALKTKRILAAGLDVTTPEPLPI-DDPLLKLDNVVILPHIGSADIETRKEMSRITARNIL 333
            :|||.:|||..||..|.|||...||... ..||....|::..||......:...||....|..|.
Human   818 EKALAQALKEGRIRGAALDVHESEPFSFAQGPLKDAPNLICTPHTAWYSEQASLEMREAAATEIR 882

  Fly   334 AALAG 338
            .|:.|
Human   883 RAITG 887

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1236	NP_649579.2	GDH	27..338	CDD:240626	85/328 (26%)
CTBP2	NP_073713.2	PHA03247	<109..572	CDD:223021	1/2 (50%)
		PHA03377	<363..575	CDD:177614	1/5 (20%)
		CtBP_dh	574..892	CDD:240624	85/325 (26%)