DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2100 and AT2G17580

DIOPT Version :9

Sequence 1:	NP_001163512.1	Gene:	CG2100 / 40707	FlyBaseID:	FBgn0037369	Length:	477	Species:	Drosophila melanogaster
Sequence 2:	NP_179349.2	Gene:	AT2G17580 / 816265	AraportID:	AT2G17580	Length:	757	Species:	Arabidopsis thaliana

Alignment Length:	527	Identity:	116/527 - (22%)
Similarity:	211/527 - (40%)	Gaps:	151/527 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 FRKVATPE--FKSIFTPELN-DLVALFKKYDYELRIAGGAVRDILMGIPPKDIDLATTATPDQMK 121
            ::||...:  .|:...||.: :::.|.::..::..:.||.|||:::...|||.|:.|||...|::
plant    59 WKKVRASDAGIKNSMIPESSMNVLRLLRRQGFDAYLVGGCVRDLILNRVPKDYDVITTADLKQIR 123

  Fly   122 QMFEKEEV--------------RMINANGEKHGTITPRINDKE-NFEVTTLRIDIRTDGRHAEVM 171
            ::|.:.:|              .:|..:  ...|:....:|.| :.|.:.:.:|.:.:..::...
plant   124 RLFHRAQVIGKRFPICHVWMGGSIIEVS--SFDTVAHSDSDLEKSKEKSGVSLDTKANKNNSLFK 186

  Fly   172 YTTDWQL-DANR------RDLTINSMFLG-FDGTVYDYFYGYDDLQERRVVFVGEADIRIKEDFL 228
            ..:.|.: |..|      ||.||||:|.. ||.|:|||..|.:||.:.::..:..|.:..|||..
plant   187 MYSGWDIKDCKRWRNSLQRDFTINSLFYNPFDFTIYDYANGMEDLTDLKLRTLVPAHLSFKEDCA 251

  Fly   229 RILRYFRFYGRIASEENNHDKATLAAIKENAKGLARISGERIWSELQKIVPGNFGAALFLEMHRC 293
            ||||..|...|:..   :..|....||.|....:|.:...|:..|:..::.....|...|.:.:.
plant   252 RILRGLRIAARLGL---SLSKDVKTAIPEFVSSVANLDQFRLIMEMNYMLAYGAAAPSILLLMKF 313

  Fly   294 NLFEYIGLP-KEPYLDEFD-----------RLCKALDQF---EKPHQPILYL------------- 330
            .|. ::.|| :..|||:..           ||...:|:.   ::|..|.|::
plant   314 KLL-HVLLPFQAAYLDQASKTSLSSSLMLVRLFSNMDKLVSCDQPADPKLWIAVLAFHIALVRNP 377

  Fly   331 ---------AGMLH------SVEDAMEMHK--------RLKLSAYER---DLARFITQEREKVGS 369
                     |.:|:      :||.|.| |:        .:..|:.:|   |||..:        |
plant   378 QEAIVVRAFAALLYHGNWSKAVEFARE-HETSVIGYAPEVSKSSRKRSDEDLAEAV--------S 433

  Fly   370 QYT-TLRDYQKLCLQK-------YIQRDFVEQLLKYSG--------------------KLELYNQ 406
            ::| .|:|.|.:...|       |:..||     |:||                    .:|.|..
plant   434 EFTCLLKDTQYVLTDKEALREALYLYPDF-----KFSGLVFIPKKKGRDVAEGFMRLSDVESYES 493

  Fly   407 LKSWVKPDFPI--RGNALAQRGLNGMRLGLVMDELKLLWADSDFQLTHDDLLKWIPNVLKK---- 465
            .|.....|:.:  :||....|.:.|.   :::|           .:|...:::.:.:|.||
plant   494 QKEGFSIDYVLLGKGNPCEVRFVLGK---IILD-----------TITEGTVIEPLNSVKKKQSTR 544

  Fly   466 ---IPSA 469
               :|:|
plant   545 NHIVPAA 551

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2100	NP_001163512.1	PcnB	71..465	CDD:223690	109/501 (22%)
		NT_ClassII-CCAase	73..210	CDD:143388	43/160 (27%)
		PolyA_pol_RNAbd	248..302	CDD:289399	10/53 (19%)
AT2G17580	NP_179349.2	NT_ClassII-CCAase	80..231	CDD:143388	39/152 (26%)
AT2G17580	NP_179349.2	PolyA_pol_RNAbd	264..327	CDD:289399	12/66 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	53	1.000	Domainoid score	I4205
eggNOG	1	0.900	-	-		E1_COG0617
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D730946at2759
OrthoFinder	1	1.000	-	-		FOG0001890
OrthoInspector	1	1.000	-	-		otm3201
orthoMCL	1	0.900	-	-		OOG6_103014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1426
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	9	8.680