DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2100 and trnt1

DIOPT Version :9

Sequence 1:	NP_001163512.1	Gene:	CG2100 / 40707	FlyBaseID:	FBgn0037369	Length:	477	Species:	Drosophila melanogaster
Sequence 2:	XP_005166087.1	Gene:	trnt1 / 415249	ZFINID:	ZDB-GENE-040625-176	Length:	431	Species:	Danio rerio

Alignment Length:	415	Identity:	194/415 - (46%)
Similarity:	274/415 - (66%)	Gaps:	37/415 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 KVATPEFKSIFTPELNDLVALFKKYDYELRIAGGAVRDILMGIPPKDIDLATTATPDQMKQMFEK 126
            ::.|.||:|:||..|..|..:|:|..:|||||||||||:|.|..|:|:|.||||||::||.||:.
Zfish    28 QLKTKEFESLFTDGLVGLAEIFQKNQFELRIAGGAVRDLLSGKRPEDVDFATTATPEEMKSMFQT 92

  Fly   127 EEVRMINANGEKHGTITPRINDKENFEVTTLRIDIRTDGRHAEVMYTTDWQLDANRRDLTINSMF 191
            ..|||||..||||||||.|::: |||||||||:|::||||||||.:|||||.||.||||||||||
Zfish    93 AGVRMINNKGEKHGTITARLHE-ENFEVTTLRVDVQTDGRHAEVEFTTDWQKDAERRDLTINSMF 156

  Fly   192 LGFDGTVYDYFYGYDDLQERRVVFVGEADIRIKEDFLRILRYFRFYGRIASEENNHDKATLAAIK 256
            ||.|||:||||.||:||:.|:|.|||.|.:||:||:||||||||||||:|:|...|:..||.||:
Zfish   157 LGLDGTLYDYFQGYEDLKNRKVRFVGSASLRIQEDYLRILRYFRFYGRVAAEPGQHEPETLEAIR 221

  Fly   257 ENAKGLARISGERIWSELQKIVPGNFGAALFLEMHRCNLFEYIGLPKEPYLDEFDRLCKALDQFE 321
            |||:|||.|||||||.||:|::.||....|...::...|.:|.|||.:..::|..::      ::
Zfish   222 ENARGLAGISGERIWVELKKMLVGNHAGHLLELVYELGLAQYTGLPADGDVEEMKQV------WQ 280

  Fly   322 KPH----QPILYLAGMLHSVEDAMEMHKRLKLSAYERDLARFITQERE---KVGSQYTTLRDYQK 379
            :.|    :|:..||.:.....|...:.:|||:|..|::|..|:.:.|.   |...::.|::.|
Zfish   281 RAHVSSPKPMTVLAALFRKQADVENLDQRLKVSREEKNLGLFLVKYRRDLVKGHDEHDTMKPY-- 343

  Fly   380 LCLQKYIQRDFVE------------QLLKYSGKLELYNQLKSWVKPDFPIRGNALAQRG-LNGMR 431
                    .||:.            :||||.|:.:|.::|:.|..|.||:.|:.|.:.| .:|..
Zfish   344 --------TDFITDSREPDTQSKVLELLKYQGENKLLDELRRWSIPRFPVSGHDLRKLGYTSGKE 400

  Fly   432 LGLVMDELKLLWADSDFQLTHDDLL 456
            :|.::.||:.:|..|.:|::.|:||
Zfish   401 IGTILQELRDMWKKSRYQMSKDELL 425

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2100	NP_001163512.1	PcnB	71..465	CDD:223690	190/406 (47%)
		NT_ClassII-CCAase	73..210	CDD:143388	93/136 (68%)
		PolyA_pol_RNAbd	248..302	CDD:289399	26/53 (49%)
trnt1	XP_005166087.1	PcnB	37..414	CDD:223690	185/393 (47%)
		NT_ClassII-CCAase	45..175	CDD:143388	91/130 (70%)
		PolyA_pol_RNAbd	213..263	CDD:289399	24/49 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580793
Domainoid	1	1.000	188	1.000	Domainoid score	I3253
eggNOG	1	0.900	-	-		E1_COG0617
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9333
Inparanoid	1	1.050	368	1.000	Inparanoid score	I2107
OMA	1	1.010	-	-		QHG48492
OrthoDB	1	1.010	-	-		D512946at33208
OrthoFinder	1	1.000	-	-		FOG0001890
OrthoInspector	1	1.000	-	-		oto40463
orthoMCL	1	0.900	-	-		OOG6_103014
Panther	1	1.100	-	-	LDO	PTHR46173
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1426
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.770