DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2100 and Trnt1

DIOPT Version :9

Sequence 1:	NP_001163512.1	Gene:	CG2100 / 40707	FlyBaseID:	FBgn0037369	Length:	477	Species:	Drosophila melanogaster
Sequence 2:	NP_001019432.1	Gene:	Trnt1 / 312616	RGDID:	1308857	Length:	434	Species:	Rattus norvegicus

Alignment Length:	414	Identity:	199/414 - (48%)
Similarity:	274/414 - (66%)	Gaps:	29/414 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 KVATPEFKSIFTPELNDLVALFKKYDYELRIAGGAVRDILMGIPPKDIDLATTATPDQMKQMFEK 126
            |:.:|||:|:||..|..|..||.|.::|||||||||||:|.|:.|:|:|.||||||.:||:||:.
  Rat    31 KLQSPEFQSLFTEGLKSLTELFAKENHELRIAGGAVRDLLNGVKPQDVDFATTATPTEMKEMFQA 95

  Fly   127 EEVRMINANGEKHGTITPRINDKENFEVTTLRIDIRTDGRHAEVMYTTDWQLDANRRDLTINSMF 191
            ..:||||..||||||||.|::: |||||||||||:.||||||||.:|||||.||.||||||||||
  Rat    96 AGIRMINNKGEKHGTITARLHE-ENFEVTTLRIDVSTDGRHAEVEFTTDWQKDAERRDLTINSMF 159

  Fly   192 LGFDGTVYDYFYGYDDLQERRVVFVGEADIRIKEDFLRILRYFRFYGRIASEENNHDKATLAAIK 256
            ||||||::|||.||.||:.::|.|||.|..||:||:|||||||||||||..:..:||:.||.||.
  Rat   160 LGFDGTLFDYFNGYADLKNKKVRFVGHAKQRIQEDYLRILRYFRFYGRIVDKPGDHDRETLEAIA 224

  Fly   257 ENAKGLARISGERIWSELQKIVPGNFGAALFLEMHRCNLFEYIGLPKEPYLDEFDRLCKALDQFE 321
            |||||||.|||||||.||:||:.|:....|...::..::..:||||....|:||:::.|.::.|.
  Rat   225 ENAKGLAGISGERIWVELKKILTGDHVNHLIHLIYDLDVASHIGLPANANLEEFNKVSKNVEGFS 289

  Fly   322 KPHQPILYLAGMLHSVEDAMEMHKRLKLSAYERDLARFITQERE---KVGSQYTTLRDYQKLCLQ 383
            .  :|:..||.:....:|..::..|||:|..|::|..||.:.|:   |.......|:.||
  Rat   290 P--KPMTVLASLFKVQDDVTKLDLRLKISKEEKNLGLFIVKNRKDLIKATDSSEPLKPYQ----- 347

  Fly   384 KYIQRDFVE------------QLLKYSGKLELYNQLKSWVKPDFPIRGNALAQRGL-NGMRLGLV 435
                 |||.            :||||.|:..|..:::.|..|.||:.|:.:.:.|: :|..:|.:
  Rat   348 -----DFVIDSREPDATARVCELLKYQGEHALLKEMQQWSVPPFPVSGHDIRKVGISSGKEIGAL 407

  Fly   436 MDELKLLWADSDFQLTHDDLLKWI 459
            :.:|:..|..|.:|:..|:||.:|
  Rat   408 LQQLREQWKKSGYQMEKDELLSYI 431

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2100	NP_001163512.1	PcnB	71..465	CDD:223690	194/405 (48%)
		NT_ClassII-CCAase	73..210	CDD:143388	94/136 (69%)
		PolyA_pol_RNAbd	248..302	CDD:289399	27/53 (51%)
Trnt1	NP_001019432.1	PcnB	40..417	CDD:223690	188/389 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340922
Domainoid	1	1.000	186	1.000	Domainoid score	I3271
eggNOG	1	0.900	-	-		E1_COG0617
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9333
Inparanoid	1	1.050	373	1.000	Inparanoid score	I2045
OMA	1	1.010	-	-		QHG48492
OrthoDB	1	1.010	-	-		D512946at33208
OrthoFinder	1	1.000	-	-		FOG0001890
OrthoInspector	1	1.000	-	-		oto95506
orthoMCL	1	0.900	-	-		OOG6_103014
Panther	1	1.100	-	-	LDO	PTHR46173
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1426
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.770