DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2100 and SPCC645.10

DIOPT Version :9

Sequence 1:	NP_001163512.1	Gene:	CG2100 / 40707	FlyBaseID:	FBgn0037369	Length:	477	Species:	Drosophila melanogaster
Sequence 2:	NP_588119.1	Gene:	SPCC645.10 / 2539578	PomBaseID:	SPCC645.10	Length:	484	Species:	Schizosaccharomyces pombe

Alignment Length:	425	Identity:	111/425 - (26%)
Similarity:	177/425 - (41%)	Gaps:	101/425 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    76 LND----LVALFKK-YDY-----------ELRIAGGAVRDILMGIPPKDIDLATTATP--DQMKQ 122
            |||    :|.|.|| .|:           |:|:|||.|||.|:|:...|:|:......  |....
pombe     7 LNDVEKKVVNLLKKTADFIESKSSSSSSLEVRLAGGWVRDKLLGLSSDDLDVTLNKVTGVDFANS 71

  Fly   123 MFEKEEVRMINANG-----EKHGTITPRINDKENFEVTTLR---IDIRTDGRHAE-------VMY 172
            :|  |.|..::::.     :..|.:|...:..::.|..||.   :||...|..||       :..
pombe    72 IF--EYVHSLDSDSVIPYKDALGKLTVNPDQSKHLETATLSLFDLDIDFVGLRAESYDDKSRIPS 134

  Fly   173 TTDW--QLDANRRDLTINSMFLGF------DGTVYDYFYGYDDLQERRVVFVGEADIRIKEDFLR 229
            .|..  :.||.|||.|:|::|...      |.|.    .||.|||.:.:|..........||.||
pombe   135 VTPGTVETDALRRDFTVNTLFFNIRTEKIEDITK----RGYKDLQTKVLVTPISPLQSFLEDPLR 195

  Fly   230 ILRYFRFYGRIASEENNHDKATLAAIKENAKGLA---RISGERIWSELQKIVPG-NFGAALFLEM 290
            |||..||..|.   |...|.:.::||::.....|   ::|.||:..|::|::.| |...||.| :
pombe   196 ILRGIRFASRF---EFTIDPSVVSAIQDPKVCKAFEKKVSKERVGEEIEKMLKGANAKLALQL-L 256

  Fly   291 HRCNLFEYI--GLPKEPYLDEFDRLCKALDQFEKPHQPILYLAGMLHSVEDAMEMHKRLKLSAYE 353
            :..|.:::.  .||.|   .|| ::.|||:..|...|.:            |:...|.:|||
pombe   257 YSTNTYQFTFDTLPAE---KEF-QIPKALEATESLFQSL------------ALTFPKLMKLS--- 302

  Fly   354 RDLARFITQEREKVG----------SQYTTLRDYQKLCLQKYIQRDFVEQLLKYSGKLELYNQLK 408
                     |.||:|          |..|.:...::..:...|.:|.::....|..:|   ||..
pombe   303 ---------EDEKIGLWLYVALIPWSSQTVMVKKKQFYIPAIIAKDKLKLRSTYVNQL---NQCC 355

  Fly   409 SWVKPDFPIRGNALAQRGLNGMRLGLVMDELKLLW 443
            :: .|.|....|..:.:  |...:|.::.:|...|
pombe   356 TF-NPIFDELVNDTSTK--NCSSIGSLIRQLNKSW 387

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2100	NP_001163512.1	PcnB	71..465	CDD:223690	111/425 (26%)
		NT_ClassII-CCAase	73..210	CDD:143388	49/174 (28%)
		PolyA_pol_RNAbd	248..302	CDD:289399	15/59 (25%)
SPCC645.10	NP_588119.1	PcnB	7..473	CDD:223690	111/425 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0617
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	57	1.000	Inparanoid score	I2010
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001890
OrthoInspector	1	1.000	-	-		oto100433
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R174
SonicParanoid	1	1.000	-	-		X1426
TreeFam	1	0.960	-	-
	8	7.850