DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1239 and lyn

DIOPT Version :9

Sequence 1:	NP_001287185.1	Gene:	CG1239 / 40706	FlyBaseID:	FBgn0037368	Length:	300	Species:	Drosophila melanogaster
Sequence 2:	NP_001004543.1	Gene:	lyn / 447804	ZFINID:	ZDB-GENE-040912-7	Length:	510	Species:	Danio rerio

Alignment Length:	183	Identity:	41/183 - (22%)
Similarity:	70/183 - (38%)	Gaps:	45/183 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   119 NSGHLSIQIARKFEVKSLVGLDI---------DRGLINDAQKTVSHLKRH---------ATPGQG 165
            |:|.|..|:.:|.|.|..:.:.:         |.|.....:..:  ::.|         .|..:|
Zfish    47 NAGLLPGQVFQKMEEKEKIVVALYPYEAIHADDLGFKKGEKLKI--IEEHGEWWKARSLTTRKEG 109

  Fly   166 IPHIQFVHGNYVLEDDVLLEIERPQFDVILCLSVTKWIHLNFCDSGLKQAFRRMYLQL-RPGGKL 229
                 |:..|||.|.|. :|.|             :|.   :.|...|.|.|::.... :||..|
Zfish   110 -----FIPSNYVAEADT-METE-------------EWF---YKDITRKDAERQLLAPANKPGSYL 152

  Fly   230 ILEPQSFDG-YKRR-KKLSEQIRDNYNAIKFRPDHFTEYLLSPEVGFAEMKLM 280
            |.|.::..| |... :.:..|.:|.....|.|......|.:||::.|:::..|
Zfish   153 IRESETSKGSYSLSIRDVDAQGQDVVKHYKIRSLDNGGYYISPKITFSDISSM 205

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1239	NP_001287185.1	Methyltransf_18	109..233	CDD:289607	29/132 (22%)
CG1239	NP_001287185.1	Bin3	191..299	CDD:284317	21/93 (23%)
lyn	NP_001004543.1	SH3_Lyn	65..120	CDD:212937	10/61 (16%)
		SH2_Src_Lyn	123..223	CDD:198227	23/99 (23%)
		PTKc_Lyn	237..508	CDD:270657
		Pkinase_Tyr	245..495	CDD:285015
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910