DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1239 and AgaP_AGAP003278

DIOPT Version :9

Sequence 1:	NP_001287185.1	Gene:	CG1239 / 40706	FlyBaseID:	FBgn0037368	Length:	300	Species:	Drosophila melanogaster
Sequence 2:	XP_560496.3	Gene:	AgaP_AGAP003278 / 3290792	VectorBaseID:	AGAP003278	Length:	288	Species:	Anopheles gambiae

Alignment Length:	282	Identity:	124/282 - (43%)
Similarity:	165/282 - (58%)	Gaps:	27/282 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 EKQVESKRLKKEESNVEATSRPPAQSPKKRLHLNGKPMQNKDLNFKYGNYKHYYGKRILNKD--- 92
            ::...|...:...||::  .:.|.::.|:|     ...|.|  .|.||||..|||.|  |.|
Mosquito    21 QENTASNSTQHSASNMQ--QKAPKRAAKER-----DKRQKK--VFPYGNYNRYYGYR--NHDATP 74

  Fly    93 FHDIRLDVLGTQPDLFRNKQLLDIGCNSGHLSIQIARKFEVKSLVGLDIDRGLINDAQKTVSHLK 157
            ..|.||.|...:.:||.:|::||||||:|.|::|:|...:..|:||:|||..||.||:|   |.|
Mosquito    75 ADDARLRVFVQRRELFESKRILDIGCNNGALTVQVALACQPASIVGIDIDGDLIRDARK---HWK 136

  Fly   158 RHATPGQ----------GIPHIQFVHGNYVLEDDVLLEIERPQFDVILCLSVTKWIHLNFCDSGL 212
            .....|.          ||..::|...||:.:|..|||:|:||||||||||||||:.|||.|.||
Mosquito   137 TTLIAGNKMGDINGRTVGIELVEFQRANYIYDDAALLELEKPQFDVILCLSVTKWMQLNFGDDGL 201

  Fly   213 KQAFRRMYLQLRPGGKLILEPQSFDGYKRRKKLSEQIRDNYNAIKFRPDHFTEYLLSPEVGFAEM 277
            :.||:|||.||.|||.||||.|.:..|||||.|:|.|..|:..|||.|..|..|||..||||:|.
Mosquito   202 RLAFKRMYRQLHPGGVLILEAQQWSSYKRRKNLNETIARNFQNIKFLPTMFERYLLGEEVGFSEC 266

  Fly   278 KLMGIPEHCKVGFKRPIQIFTK 299
            ..:.:..|...||:||:|::.|
Mosquito   267 TELPVQRHSAAGFQRPLQMYRK 288

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1239	NP_001287185.1	Methyltransf_18	109..233	CDD:289607	68/133 (51%)
CG1239	NP_001287185.1	Bin3	191..299	CDD:284317	61/107 (57%)
AgaP_AGAP003278	XP_560496.3	Methyltransf_18	91..222	CDD:289607	68/133 (51%)
AgaP_AGAP003278	XP_560496.3	Bin3	180..288	CDD:284317	61/107 (57%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	91	1.000	Domainoid score	I14264
eggNOG	1	0.900	-	-		E1_KOG2899
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H80813
Inparanoid	1	1.050	215	1.000	Inparanoid score	I6023
OMA	1	1.010	-	-		QHG55475
OrthoDB	1	1.010	-	-		D1185441at2759
OrthoFinder	1	1.000	-	-		FOG0003359
OrthoInspector	1	1.000	-	-		oto106384
Panther	1	1.100	-	-	O	PTHR12315
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2246
TreeFam	1	0.960	-	-
	13	12.940