DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1239 and mepceb

DIOPT Version :9

Sequence 1:	NP_001287185.1	Gene:	CG1239 / 40706	FlyBaseID:	FBgn0037368	Length:	300	Species:	Drosophila melanogaster
Sequence 2:	XP_001921729.2	Gene:	mepceb / 100151157	ZFINID:	ZDB-GENE-110411-13	Length:	629	Species:	Danio rerio

Alignment Length:	336	Identity:	103/336 - (30%)
Similarity:	166/336 - (49%)	Gaps:	80/336 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 KRLKKEESNVEATSRPPAQSPKKRL-------H------LNGKP--------MQNKDLNFKY--G 78
            :.:.:.:|.:..|..||.    |||       |      .:|.|        .|.:....||  |
Zfish   296 RTVSRSDSRLSITPTPPT----KRLITHTQTFHTPVIGGASGAPPLGAERSHEQQRRPRRKYHNG 356

  Fly    79 NYKHYYGKRILNKDFHDIRLDVLGTQPDLFRNKQLLDIGCNSGHLSIQIARKFEVKSLVGLDIDR 143
            .|..|||.|..:.. .|.||.:.  .|:.|..|::||:|||:||:::.||:......::|||||.
Zfish   357 AYSRYYGYRTPSMT-ADPRLALF--NPEWFSGKKVLDVGCNTGHVTLAIAKHCSPAHILGLDIDG 418

  Fly   144 GLINDAQKTVSHL------KRHATPGQG------IP----------------------------- 167
            .|:..|::.:.|.      ::.|..|:|      :|
Zfish   419 ALVQAARQNLRHFLSELQDRQQAGAGEGSEVTGLVPLMDLQLVLPRFPVSFMRCRGPIAAPPIMH 483

  Fly   168 --------HIQFVHGNYVLEDDVLLEIERPQFDVILCLSVTKWIHLNFCDSGLKQAFRRMYLQLR 224
                    ::.|:.|:||.:.|..:..:..::|||||||:|||:|||:.|:|:::.|.|:|..|.
Zfish   484 QSLGQFPSNVCFLKGDYVPDSDAEVVSQSAEYDVILCLSLTKWVHLNYGDAGIQRLFGRIYRHLL 548

  Fly   225 PGGKLILEPQSFDGYKRRKKLSEQIRDNYNAIKFRPDHFTEYLLSPEVGFAEMKLMGIPEHCKVG 289
            |||.||||||.:..|.|.|:|::..|.||::|:.:||.|:.:|:: ||||:..:|:|.|.....|
Zfish   549 PGGVLILEPQPWSSYSRHKRLTDVTRRNYSSIRLKPDKFSSFLMA-EVGFSSYELIGTPRASPKG 612

  Fly   290 FKRPIQIFTKS 300
            .:|.:.:|.||
Zfish   613 LQRSVYLFHKS 623

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1239	NP_001287185.1	Methyltransf_18	109..233	CDD:289607	52/172 (30%)
CG1239	NP_001287185.1	Bin3	191..299	CDD:284317	50/107 (47%)
mepceb	XP_001921729.2	Methyltransf_18	384..557	CDD:289607	52/172 (30%)
mepceb	XP_001921729.2	Bin3	515..622	CDD:284317	50/107 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170589284
Domainoid	1	1.000	124	1.000	Domainoid score	I5449
eggNOG	1	0.900	-	-		E1_KOG2899
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1185441at2759
OrthoFinder	1	1.000	-	-		FOG0003359
OrthoInspector	1	1.000	-	-		otm24354
orthoMCL	1	0.900	-	-		OOG6_103556
Panther	1	1.100	-	-	O	PTHR12315
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2424
SonicParanoid	1	1.000	-	-		X2246
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	13	12.740