Protein Alignment plx and Grtp1

DIOPT Version :10

• Sequence 1: NP_001163511.1
• Gene: plx / 40704
• FlyBaseID: FBgn0261261
• Length: 1572
• Species: Drosophila melanogaster
• Sequence 2: NP_001355787.1
• Gene: Grtp1 / 66790
• MGIID: 1914040
• Length: 359
• Species: Mus musculus
• Alignment Length: 319
• Identity: 92/319 - (28%)
• Similarity: 150/319 - (47%)
• Gaps: 45/319 - (14%)

  Fly   895 YEE-----IVPCDKQLIERWEQIIERNSTQIGNKKDPKVLGHAIRTGVPRSKRGDVWTFLAEQHS 954
            |||     :|...|:.| :|.::::.|.   |.:|...|..: :|.|:|...|..||.      :
Mouse    33 YEEFFSTYLVILTKRAI-KWSKLLKGNG---GVRKSVTVKRY-VRKGIPLEHRARVWM------A 86

  Fly   955 MNTAPVDTKRFPNFNTPYHMLL--KHLTEHQHAIFIDLGRTFPNHQFYK---DPLGLGQLSLFNL 1014
            ::.|.....:.|.:   ||.||  :..:....||..||.||||::..::   ||  ..|.:|:|:
Mouse    87 VSGAQARMDQSPGY---YHRLLEGESSSSLDEAIRTDLNRTFPDNVMFRKTADP--CLQKTLYNV 146

  Fly  1015 LKAYSILDPELGYCQ-----------------GLGFICGVLLLHC-DEANSFQLLKHLMFRRNMR 1061
            |.||.:.:|::||||                 |:.||.|.|:|.. :|..||.||..|: .|.:.
Mouse   147 LLAYGLHNPDVGYCQCCAQKPGSSAGLRSSLTGMNFIAGYLILITKNEEESFWLLDALV-GRILP 210

  Fly  1062 TKYLPDMKKFQLQLYQLSRLVKDHLPDLYVWLDQNDVSPTLYAAPWILTVFSSQFPLGFVARVFD 1126
            ..|.|.|...:.....|:.||:..||.:...:|.:.|..||..:.|.:.:|....|:..|.|::|
Mouse   211 DYYSPAMLGLKTDQEVLAELVRMKLPAVAALMDGHGVLWTLLVSRWFICLFVDILPVETVLRIWD 275

  Fly  1127 LLFLESSDVIFKFAIALLSVHKQQLLAKDNFEEIMDYLKTVVPKMEHTCMEQIMKLVFS 1185
            .||.|.|.:||:.|:.|:..|::.:|...:..:|.|..|.:......|.....|:.:||
Mouse   276 CLFNEGSKIIFRVALTLIKQHQEFILEASSIPDICDKFKQITKGDFVTECHAFMQKIFS 334

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
plx	NP_001163511.1	PTB_TBC1D1_like	301..601	CDD:269967
		DUF3350	831..880	CDD:463365
		TBC	933..1152	CDD:214540	73/241 (30%)
		COG4372	<1190..>1353	CDD:443500
Grtp1	NP_001355787.1	TBC	71..301	CDD:214540	73/241 (30%)