Protein Alignment plx and tbc1d10ab

DIOPT Version :10

• Sequence 1: NP_001163511.1
• Gene: plx / 40704
• FlyBaseID: FBgn0261261
• Length: 1572
• Species: Drosophila melanogaster
• Sequence 2: XP_073770520.1
• Gene: tbc1d10ab / 562628
• ZFINID: ZDB-GENE-081105-145
• Length: 479
• Species: Danio rerio
• Alignment Length: 496
• Identity: 124/496 - (25%)
• Similarity: 201/496 - (40%)
• Gaps: 106/496 - (21%)

  Fly   807 AETHQGS---WRQAI--------LNSVVTPSKGLDSEVPTEFLSPMRKPAKRGKRDAAELRELWR 860
            |:.|.|:   |:...        |....:.|:|.|||: ..|.:...:|.|.|....|:
Zfish     2 AKLHAGNGVHWKDGKSQRSTADGLAEQESSSRGSDSEL-NGFANTEVQPDKYGFIGGAQ------ 59

  Fly   861 TAIRQTIMLNRMETENAMLQARQNENELKRIKLDYEEIVPCDKQLIERWEQIIERNSTQIGNKKD 925
                ||              |.:|.:::....|...|....|  ::..|::.:.        ||.
Zfish    60 ----QT--------------AGENSDDIPPDVLRQREAKWLD--MLNNWDKWMA--------KKH 96

  Fly   926 PKVLGHAIRTGVPRSKRGDVWTFLA------EQH-----SMNTAPVDTKRFPNFNTPYHMLLKHL 979
            .||.... :.|:|.|.||..|.:|:      ||:     .:::.|.|.|..
Zfish    97 KKVKLRC-QKGIPPSLRGRAWLYLSGGKVKKEQNPGKFKELDSQPGDPKWL-------------- 146

  Fly   980 TEHQHAIFIDLGRTFPNHQFYKDPLGLGQLSLFNLLKAYSILDPELGYCQGLGFICGVLLLHCDE 1044
                ..|..||.|.||.|:.:....|.||..||.:||||::..||.||||....|..|||:|...
Zfish   147 ----DVIEKDLHRQFPFHEMFVARGGHGQQDLFRVLKAYTLHRPEEGYCQAQAPIAAVLLMHMPA 207

  Fly  1045 ANSFQLLKHLMFRRNMRTKYLPDMKKFQLQLYQLS-----RLVKDHLPDLYVWLDQNDVSPTLYA 1104
            .::|..|..:.      .||||......|:..||.     .|:|...|..:..|.:..:.|.||.
Zfish   208 EDAFWGLVQIC------EKYLPGYYSAGLEAIQLDGEILFALLKRVSPVAHRHLKKYKIDPILYM 266

  Fly  1105 APWILTVFSSQFPLGFVARVFDLLFLESSDVIFKFAIALLSV---HKQQLLAKDNFEEIMDYLKT 1166
            ..|.:..||...|...|.||:|:.|.|...:||:..:.||..   ..::|.|.....|.|:.|::
Zfish   267 TEWFMCAFSRTLPWASVLRVWDMFFCEGVKIIFRVGLVLLKCMLGSPEKLKACQGQYETMELLRS 331

  Fly  1167 VVPK--MEHTCMEQIMKL-VFSMDIGK----QLAEYKVEYNVLQEEITTTNHHLE-MLNREKTQN 1223
            :.|:  .|...:::::.| |...||.|    ||..:|..:..|..:.....|..: ::..|....
Zfish   332 IEPRYMQEAFLVQEVIDLPVSERDIEKEHLSQLRRWKETHGELHCKSPPRMHGAKAIMAAEPPSR 396

  Fly  1224 QHLEQQ----LQFAQSSIAQLETTRSSQQAQITTLQSQVQS 1260
            :.|:|.    ::.|:|   |.||.:.::::: |..:.:.||
Zfish   397 KDLKQNPTIIVEAAES---QTETGKKAKKSK-TEKRKETQS 433

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
plx	NP_001163511.1	PTB_TBC1D1_like	301..601	CDD:269967
		DUF3350	831..880	CDD:463365	9/48 (19%)
		TBC	933..1152	CDD:214540	69/237 (29%)
		COG4372	<1190..>1353	CDD:443500	17/80 (21%)
tbc1d10ab	XP_073770520.1	None