Protein Alignment plx and grtp1

DIOPT Version :10

• Sequence 1: NP_001163511.1
• Gene: plx / 40704
• FlyBaseID: FBgn0261261
• Length: 1572
• Species: Drosophila melanogaster
• Sequence 2: NP_001005632.1
• Gene: grtp1 / 448089
• XenbaseID: XB-GENE-950226
• Length: 342
• Species: Xenopus tropicalis
• Alignment Length: 346
• Identity: 94/346 - (27%)
• Similarity: 155/346 - (44%)
• Gaps: 54/346 - (15%)

  Fly   895 YEEIVPCDKQLIER----WEQIIERNSTQIGNKKDPKVLGHAIRTGVPRSKRGDVWTFLA---EQ 952
            |||.:.....::.|    |.:::::::..   :|:.||..: ||.|:|...|..||..::   .|
 Frog    31 YEEFIARYHVVLTRRAIKWSKLLQQSAAV---EKNMKVKRY-IRKGIPNEHRSHVWMVVSGAQAQ 91

  Fly   953 HSMNTAPVDTKRFPNFNTPYHMLLKHLTEHQ------HAIFIDLGRTFP-NHQFYKDPLGLGQLS 1010
            ..|||.               ...:..||.:      ..:..||.|||| |..|.|:.....|..
 Frog    92 MDMNTG---------------YFRRMFTEGEKNPKLLDLVITDLNRTFPDNVLFQKNANPSLQKD 141

  Fly  1011 LFNLLKAYSILDPELGYCQGLGFICGVLLLHC-DEANSFQLLKHLMFRRNMRTKYLPDMKKFQLQ 1074
            |:|:|.||...:..:|||||:.||.|.|:|.. ||..:|.|:..|: .:.:...|.|.|...:..
 Frog   142 LYNVLVAYGQHNKTVGYCQGMNFIAGYLILVTKDEEKAFWLMDALI-GQILPDYYSPAMTGLKTD 205

  Fly  1075 LYQLSRLVKDHLPDLYVWLDQNDVSPTLYAAPWILTVFSSQFPLGFVARVFDLLFLESSDVIFKF 1139
            ...|..|||..:|.:...::.:.|..||..:.|.:.:|....|:..|.|::|.||.|.|.|||:.
 Frog   206 QEVLGDLVKKKIPSVAQLIETHGVMWTLLVSRWFICLFIDILPVETVLRIWDCLFFEGSKVIFRV 270

  Fly  1140 AIALLSVHKQQLLAKDNFEEIMDYLKTVVPKME-----HTCMEQIMKLVFSMDIGKQLAEYKVEY 1199
            |:.|:...:..::...||.:|.|..|.:. |.|     |..|::|.....|:.        |...
 Frog   271 ALTLIKQSQASIMEARNFPDICDKFKEIT-KGEFVTDCHYFMQKIFAEPGSLS--------KTTI 326

  Fly  1200 NVLQEEITTTNHHLEMLNREK 1220
            :.|:|:     ..|::::.||
 Frog   327 DKLREK-----QRLKLISEEK 342

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
plx	NP_001163511.1	PTB_TBC1D1_like	301..601	CDD:269967
		DUF3350	831..880	CDD:463365
		TBC	933..1152	CDD:214540	69/229 (30%)
		COG4372	<1190..>1353	CDD:443500	6/31 (19%)
grtp1	NP_001005632.1	TBC	69..283	CDD:214540	69/229 (30%)