DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment plx and CG5916

DIOPT Version :9

Sequence 1:	NP_001163511.1	Gene:	plx / 40704	FlyBaseID:	FBgn0261261	Length:	1572	Species:	Drosophila melanogaster
Sequence 2:	NP_001287357.1	Gene:	CG5916 / 41960	FlyBaseID:	FBgn0038401	Length:	330	Species:	Drosophila melanogaster

Alignment Length:	306	Identity:	82/306 - (26%)
Similarity:	147/306 - (48%)	Gaps:	50/306 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   908 RWEQIIERNS--TQIGNKKDPKVLGHAIRTGVPRSKRGDVWTFLAEQHSMNTAPVDTKRFPNFNT 970
            :||.|:::|:  ||:..|     |...||.|:|...|.|||.      .::.|....:|.|:
  Fly    45 KWEAILQQNTDLTQVDAK-----LKRYIRKGIPGPYRPDVWM------KISGAAAAQRRSPD--- 95

  Fly   971 PYHMLLKHL-------TEHQHAIFIDLGRTFPNHQFYKDPLGLGQLSLFNLLKAYSILDPELGYC 1028
                |.::|       .|...:|.|||.||||::..:    .:.:..|:|:|.||:..:.::|||
  Fly    96 ----LFRNLLRTEPFDKEISDSISIDLPRTFPDNIHF----DMKKQRLYNILIAYAHHNRDVGYC 152

  Fly  1029 QGLGFICGVLLLHC-DEANSFQLLKHLMFRRNMRTKY--------LPDMKKFQLQLYQLSRLVKD 1084
            |||.:|.|:||:.. ||..||.||||::  .|:..:|        |.|:..|:       .||..
  Fly   153 QGLNYIAGLLLIVTDDEEKSFWLLKHIV--ENIVPQYHSHNMANLLRDLAVFR-------ELVIR 208

  Fly  1085 HLPDLYVWLDQNDVSPTLYAAPWILTVFSSQFPLGFVARVFDLLFLESSDVIFKFAIALLSVHKQ 1149
            .:|.:...:|...:...:.|:.|.:.:|:...|:..|.|::|.:|.|...::|:.|:.:...||.
  Fly   209 RIPAVNRHVDNLGLPYPVIASKWFICIFAEVLPVETVLRIWDCVFAEGYKIVFRAALTMFVTHKN 273

  Fly  1150 QLLAKDNFEEIMDYLK-TVVPKMEHTCMEQIMKLVFSMDIGKQLAE 1194
            .:|..|:...:.:..: |::.....|.....::.:||:.:.:...|
  Fly   274 AILGCDDIAALANLFRDTMIQDNIVTDCHGFVEAMFSLRLKRSELE 319

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
plx	NP_001163511.1	PTB_TBC1D1_like	301..601	CDD:269967
		DUF3350	835..880	CDD:288663
		TBC	933..1152	CDD:214540	67/234 (29%)
		RILP-like	<1176..1267	CDD:304877	3/19 (16%)
CG5916	NP_001287357.1	TBC	67..276	CDD:214540	67/234 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456552
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR22957
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940