Protein Alignment plx and RN-tre

DIOPT Version :10

• Sequence 1: NP_001163511.1
• Gene: plx / 40704
• FlyBaseID: FBgn0261261
• Length: 1572
• Species: Drosophila melanogaster
• Sequence 2: NP_652381.1
• Gene: RN-tre / 36554
• FlyBaseID: FBgn0020620
• Length: 571
• Species: Drosophila melanogaster
• Alignment Length: 596
• Identity: 125/596 - (20%)
• Similarity: 231/596 - (38%)
• Gaps: 156/596 - (26%)

  Fly   873 ETENAMLQARQNENE--LKRIKLDYEEIVPCDKQLIERWE------------------------- 910
            |.:.|:::..::|.|  .:|.:|..:     ...:::.||
  Fly     5 EQQEALVKRAEDEREDIFRRYELGLD-----PSNVVDSWENPTFEIYHRTDKYGFLHDSRLPSTR 64

  Fly   911 --QIIERNSTQI-GNKKDPKVLGH----------AIRTGVPRSKRGDVWTFLAE-QHSMNTAPVD 961
              |.:.||..:: .:||..|:|..          .:..|:|...|...|..|.: |.|:|.
  Fly    65 DAQEVHRNKIEMERDKKWMKMLNQWPPPQDKLHKRVYKGIPDRVRMVAWNKLLDIQQSINN---- 125

  Fly   962 TKRFPNFNTPYHML---LKHLTEHQHAIFIDLGRTFPNHQFYKDPLGLGQLSLFNLLKAYSILDP 1023
                 |......||   .|:.||.:. |..|:.|.|.::..:::...:.|.||||:|.||||.:.
  Fly   126 -----NAGVYLRMLQLARKYSTETRQ-IDADVNRQFRDNLAFRERYSVKQCSLFNVLNAYSIYNS 184

  Fly  1024 ELGYCQGLGFICGVLLLHCDEANSFQLLKHLMF--RRNMRTKYLPDMKKFQLQLYQLSRLVKDHL 1086
            |||||||:..:.|||||:..|..:|..|..|:.  :..|...::....|....:....|::...:
  Fly   185 ELGYCQGMACVAGVLLLYLHEEEAFWALNTLITDQKYGMHGLFIEGFPKLTRFIDHHDRIMSKIM 249

  Fly  1087 PDLYVWLDQNDVSPTLYAAPWILTVFSSQFPLGFVARVFDLLFLESSDVIFKFAIALLSVHKQQL 1151
            ..|:....:::|...|||..|...||..:.|.....||:|:..|:...||...||.:|.:||.:|
  Fly   250 RKLHKHFTKHNVDALLYAIKWFFVVFVERVPFSLSLRVWDIFMLDGDRVILSMAITILYLHKDEL 314

  Fly  1152 LAKDNFEEIMDYLKTVVPKM-------EHTCMEQIMKLVFSM----------------------- 1186
            |...:.:.|::||:..:.|.       ....:|::||.:..:
  Fly   315 LRLKDMDAIIEYLQVRLHKNFGYSDDDAIQALERVMKKLKDLKLDVPPPAKSNEFPTRKLGDFVE 379

  Fly  1187 -DIGKQLAEYKVEYNVLQEEITTTNHHLEMLNREKTQNQHLEQQLQFAQS--------------S 1236
             |:.|::...:.:|...::::.|     ::::|::.....::..:.:..|              |
  Fly   380 ADMEKKIGRRRNDYTDAEKQVIT-----DVISRQEQNAIDVQSTVSYETSECATGDGYSMKTFES 439

  Fly  1237 IAQLETTRSSQQAQ-------ITTLQS-QVQSLELTIQTLGRYVGQLVEHNPDLELPNEVRRMLQ 1293
            |..|.|:.::....       :||:.| |..:...:|..|     ..::.:|.|. ||.::.|..
  Fly   440 ITSLATSPANSSYSLYSNGFVVTTIDSEQDPARSQSIHNL-----SYLQTHPALP-PNGLQHMRH 498

  Fly  1294 QL-DDLDRQRRKPIFTERKIGKSVSVNSHLGFPLKVLEELTERDELGSPQKQKKEKTPFFEQLRQ 1357
            .. .|.|.:.|            :.::..|        |:.:|.:|....|....:..:..|
  Fly   499 SFSSDSDSRNR------------IDLDQAL--------EVLQRQQLPLHPKTPSSQVVYIVQ--- 540

  Fly  1358 QQQQHRLNGGG 1368
                   ||||
  Fly   541 -------NGGG 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
plx	NP_001163511.1	PTB_TBC1D1_like	301..601	CDD:269967
		DUF3350	831..880	CDD:463365	2/6 (33%)
		TBC	933..1152	CDD:214540	67/224 (30%)
		COG4372	<1190..>1353	CDD:443500	28/185 (15%)
RN-tre	NP_652381.1	TBC	100..315	CDD:214540	67/224 (30%)