Protein Alignment plx and CG1695

DIOPT Version :9

• Sequence 1: NP_001163511.1
• Gene: plx / 40704
• FlyBaseID: FBgn0261261
• Length: 1572
• Species: Drosophila melanogaster
• Sequence 2: NP_728346.2
• Gene: CG1695 / 33046
• FlyBaseID: FBgn0031116
• Length: 1192
• Species: Drosophila melanogaster
• Alignment Length: 1414
• Identity: 252/1414 - (17%)
• Similarity: 440/1414 - (31%)
• Gaps: 489/1414 - (34%)

  Fly     1 MKTRLVSLTFRGSASVDPRYSASMLPWTINDIRSTESYTKLSVGIENGILESYNSDFELQFSHPL 65
            :|.||:       |||.......|          .|:.||..|..|:..:.|.....|...||.|
  Fly    29 LKERLI-------ASVKKEVKQLM----------EEAVTKKYVHEESSSVTSLCGAVEACLSHGL 76

  Fly    66 -KHIVGMCR------IIHK-----PQAKSIGNGFLQLK------SSAGQTSSSSAVA------SS 106
             :..:|:.:      :|.|     |:|..:....|:|:      :.:|:.||.|:.:      .|
  Fly    77 RRRALGLFKTSSTTALIQKIAKICPEADYVSRRLLELELAQESHAVSGKRSSCSSDSIIKPKLLS 141

  Fly   107 MGGAASSSLT---------------GNGL-----------------------------------R 121
            .|..:|:|:|               |.|.                                   |
  Fly   142 KGSGSSNSVTTINTVTNGAGAGPGGGGGASAPLGKYLWIRLALHEKRLAKIIEHLVSNANSYYDR 206

  Fly   122 HTLTASTSYGSLSSS---AACAYQLQLQQSAEASAEQPQNFMEFQGPITGLVYLLKDPKDPLLHI 183
            ..|.|...|||:.||   ..||.:....::|:                    :...||
  Fly   207 EALVADPDYGSILSSLLVGPCALEFTRAKTAD--------------------HYWSDP------- 244

  Fly   184 YLFECEAVEEMAELMHQMRDPAHTLGGSVGSIPQTLIGGGGGSHGNSNGALNGIHATPATNLKMS 248
                  ..:|:.: .|::                        |.||         .||.|..:..
  Fly   245 ------CADELVQ-RHRI------------------------SSGN---------RTPPTTHRPI 269

  Fly   249 EAMRNAQHDTSPNPVSSKMKA------SKSYTHGLSSSSGTVNIPTSTSAQSNLSLL-ADIS--- 303
            ...:.:.|.:|.:..|...||      :|.|...|..:|.|    |....::|:.:| .|:|
  Fly   270 INFKRSLHTSSEDTSSGSFKACSPASVAKDYVESLHQNSRT----TLLYGKNNVLVLPKDVSEPM 330

  Fly   304 PNHTHFFEVMYVGKIRVSQKRVPNTFIDDALPKFKAYDAQRLRLLQNRKMSLSSEGGVGIEAKPS 368
            |.:....:.:....|:.:..::.|.:.|                         .:||      ..
  Fly   331 PGYLSLHQSIQSLTIKWTPNQLMNGYND-------------------------GDGG------DK 364

  Fly   369 SSLKSHDLKEEDEE----EQEQHKGHDD-------SQDSQAKPLVQLQLTGAEEGAAPRPLEDNK 422
            |...|:.|....:|    ...|::|.|.       .||...:|.:..
  Fly   365 SFYWSYALNINVDEIVYVHCHQNRGGDTGGTIILVGQDGVQRPPIHF------------------ 411

  Fly   423 ENKSPEKRPLLRGQSQIELGHKEHSDGSQPLAAN-------------------SQLEAPNVIVNK 468
                ||...|....|.:|.|...|.....||.:.                   |.:||...:.::
  Fly   412 ----PEGGHLQAFLSCLETGLLPHGQLDPPLWSQRGIGKLFPWPKSVRRHILPSVMEAGGSVTDE 472

  Fly   469 QP---------------------------TPPRDQGVG----TGTASASAGPSQLHPNYAMDNIP 502
            .|                           :.||.:.:|    ||::..|:....:
  Fly   473 TPIDYVFRVVSKCQHEEFLASHPILELGRSSPRRKHLGSCSTTGSSDCSSKSLSI---------- 527

  Fly   503 KQRDRSASQGCIPPYVEQNR-TMVFLVGRCDLRLISPDRKQVLLYKDFKDVASCVHGQKSLDHF- 565
               |:|:   |..|.::.:: |.:.||  |     |..|:|::....:..:|.|.|......|.
  Fly   528 ---DQSS---CETPLIQASQSTSIELV--C-----STMRRQIISRAFYGWLAYCRHLSTVRTHLS 579

  Fly   566 ----GIICREL---------------NNDG------------YIGYVFKCQSEHVCDDIVAAIAQ 599
                |.|..:|               :.||            |.|.|.....:.|...::.  ..
  Fly   580 GLVNGRIMPDLAADEEGLTRGKWLAMHEDGVVTGDLELYRLVYFGGVEPELRKEVWPYLLG--HY 642

  Fly   600 AFDTCAEQKKKQDTQIFSCEHCPMLWYHKLCTD---VEGL---SEKKTQALILRRIETLSDDEQE 658
            .|.:..|::||||.   :|:|    :|....::   ||.:   .||:..||.:.::..    ||.
  Fly   643 DFGSTPEERKKQDE---TCKH----YYETTMSEWLAVEAIVRQREKEKTALAVAKLSA----EQA 696

  Fly   659 IVWAKFCGSEKTNSPVAEQNQFLMMLLRAHCESRQQRHVHDTAENRSEFLNQY------------ 711
            .:.|....|...:..:|..:|.| .|...:.|..|:..|.|..||.....|.:
  Fly   697 RLAANATSSSNPHQKLANGSQQL-QLEHGNGEEDQENLVLDEGENDVFDDNDFSDISDPGDLFDE 760

  Fly   712 --LGGSTIFMKAKRSLTNSFDNLLKRKPSKDDIAVPSHNLRDIRE------------GSAEPLGT 762
              ||...    .::..:|..:.:.:::..::|  ...|:.|::..            .:.|||..
  Fly   761 PELGQEA----EEQEQSNLEEEVFEKQEDEED--QEDHDQREMPRLSEKLVLEFQNIDNMEPLRL 819

  Fly   763 QSPPEGFRSRSNTVGASPSSKPTAEQL---KSPMMDIFIKVGN---SPKEAETHQGSWRQAILNS 821
            |..........|.:|....|......|   .||....:..|||   ...||:
  Fly   820 QENCFADSETENDLGLGLDSSGNILMLSIKSSPSTSSYETVGNEFLDMAEAK------------- 871

  Fly   822 VVTPSKGLDSEVPTEFLSPMRKPAKRGKRDAAELRELWRTAIRQTIMLNRMETENAMLQARQNE- 885
                   |:.|.|...||.... |...:.|..:..|..:.|....|      ||.|.|.|..::
  Fly   872 -------LEEEEPPGQLSKFHS-ADDVRLDNQDEEESSQPATAVII------TEAASLDALDDDP 922

  Fly   886 -NELKRIKLDYEEIVPCDKQLIERWEQIIERNSTQIGNKKDPKVLGHAIRTGVPRSKRGDVWTF- 948
             .|....|......:..|..::...:.:.|..|..:.                |.|..|.|::.
  Fly   923 TEEFTSRKTSLMSPLNEDITVVASLDALQEPKSACVS----------------PASSNGGVYSVE 971

  Fly   949 LAEQHSMNTAPVDTKRFPNFNTPYHMLLKHLTEHQHAIFIDLGRTFPNHQFYKDPLGLGQLSLFN 1013
            |.||..:|.                          |.|..|:.|...|:.::.:. .|.:|.  |
  Fly   972 LLEQFGLNL--------------------------HRIEKDVQRCDRNYWYFANE-NLDKLR--N 1007

  Fly  1014 LLKAYSILDPELGYCQGL-GFICGVLLLHCDEANSFQLLKHLMFRRNMRTKYLPDMKKFQLQLYQ 1077
            ::..|.....::||.||: ..:..:|::..||:.|:.....||.|   ..:..|......:....
  Fly  1008 VISTYVWEHLDVGYMQGMCDLVAPLLVIFDDESLSYSCFCKLMER---MIENFPSGGAMDMHFAN 1069

  Fly  1078 LSRLVKDHLPDLYVWLDQN-DVSPTLYAAPWILTVFSSQFPLGFVARVFDLLF----LESSDVIF 1137
            :..|::....::|..:|.| |.:...:...|.|..|..:.....|...:::::    :.|...:.
  Fly  1070 MRSLIQILDSEMYDLMDSNGDYTHFYFCYRWFLLDFKRELVYDDVFATWEVIWAAKHIASGHFVL 1134

  Fly  1138 KFAIALLSVHKQQLLAKDNFEEIMDYLKTVVPKMEHTCMEQIMKLVFSM 1186
            ..|:|||..::..:|:  |..:..|.:|......|....:.|::|..|:
  Fly  1135 FLALALLETYRDIILS--NSMDFTDVIKFFNEMAERHNAQSILQLSRSL 1181

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
plx	NP_001163511.1	PTB_TBC1D1_like	301..601	CDD:269967	61/396 (15%)
		DUF3350	835..880	CDD:288663	10/44 (23%)
		TBC	933..1152	CDD:214540	43/225 (19%)
		RILP-like	<1176..1267	CDD:304877	3/11 (27%)
CG1695	NP_728346.2	RUN	63..237	CDD:280855	33/173 (19%)
		PH_RUTBC	310..485	CDD:275431	35/231 (15%)
		SRP68-RBD	<648..>713	CDD:304552	18/75 (24%)
		TBC	947..1124	CDD:214540	40/224 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456550
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR22957
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940