Protein Alignment plx and Evi5

DIOPT Version :9

• Sequence 1: NP_001163511.1
• Gene: plx / 40704
• FlyBaseID: FBgn0261261
• Length: 1572
• Species: Drosophila melanogaster
• Sequence 2: XP_006250585.2
• Gene: Evi5 / 100360066
• RGDID: 2322879
• Length: 882
• Species: Rattus norvegicus
• Alignment Length: 693
• Identity: 163/693 - (23%)
• Similarity: 301/693 - (43%)
• Gaps: 152/693 - (21%)

  Fly   786 AEQLKSPMMDIFIKVGNSPKEAETHQGSWRQAILNSVVTPSKGLDSEVPTEFLS-PMRKPAKRGK 849
            ||:|.|.:..:        |...:|..|   .:.:.|.:||..|.:...:..|| |.:.|:...|
  Rat    37 AEKLSSTLSWV--------KNTVSHTVS---QMASQVASPSASLHTTSSSTTLSTPTQSPSSPSK 90

  Fly   850 RDAAELRELWRTAIRQTIMLNRMETENAMLQ-----------ARQN-----------ENELKRIK 892
            ....:|.           :|.::|.:|.:::           :|:|           .:.|..::
  Rat    91 LSPDDLE-----------LLAKLEEQNRLIETDSKSLRSVNGSRRNSGSSLVSSSSASSNLSHLE 144

  Fly   893 LDYEEIVPCDKQLIERWEQIIERNSTQIGNKKDPKVLGHAIRTGVPRSKRGDVWTFLAEQHSMNT 957
               |:......:::..|:.:         .||..|.:...:|.|:|...|..||..|.:..:|
  Rat   145 ---EDSWILWGRIVNEWDDV---------RKKKEKQVKELVRKGIPHHFRAIVWQLLCDAQTM-- 195

  Fly   958 APVDTKRFPNFNTPYHMLLKHLTEHQHAIFIDLGRTFPNHQFYKDPLGLGQLSLFNLLKAYSILD 1022
             ||..:        |..|||..:..:..|..|:.||:|.|.|:|:...|||..|||::||||::|
  Rat   196 -PVKDQ--------YSELLKMTSPCEKLIRRDIARTYPEHNFFKEKDSLGQEVLFNVMKAYSLVD 251

  Fly  1023 PELGYCQGLGFICGVLLLHCDEANSFQLLKHLMFRRNMRTKYLPDMKKFQLQLYQLSRLVKDHLP 1087
            .|:|||||..||.|:|||...|..:|.:...||....:|..:.|.|.:..|.:||...:::::||
  Rat   252 REVGYCQGSAFIVGLLLLQMPEEEAFCVFFKLMQDYRLRELFKPSMAELGLCMYQFECMIQEYLP 316

  Fly  1088 DLYVWLDQNDVSPTLYAAPWILTVFSSQFPLGFVARVFDLLFLESSDVIFKFAIALLSVHKQQLL 1152
            :|:|.........::||:.|.||:|.:.|||....|:||:...|..:::|:..:|||.:::.:|:
  Rat   317 ELFVHFQSQSFHTSMYASSWFLTIFLTTFPLPIATRIFDIFMSEGLEIVFRVGLALLQMNQAELM 381

  Fly  1153 AKDNFEEIMDYLKTVVPKMEHTCMEQIMKLVFSMDIGKQLAEYKVEYN-----VLQEEITT--TN 1210
            ..| .|.::.:.:.|:|.......|::::           :.|:|:||     .|::|.||  |.
  Rat   382 QLD-MEGMLQHFQKVIPHQFDGGPEKLIQ-----------SAYQVKYNSKKMKKLEKEYTTIKTK 434

  Fly  1211 HHLEM--LNREKTQNQHLEQQLQFAQSSIAQL-------ETTRSSQ-------QAQITTLQSQVQ 1259
            ...|.  :.|.:|:|:.|:|:::..:...|.|       :.||:.:       :.::.|::.|..
  Rat   435 EMEEQGEIKRLRTENRLLKQRIETLEKESASLADRLIQGQVTRAQEAEENYLIKRELATIKQQTD 499

  Fly  1260 SLELTIQTLGRYVGQLVEH----------NPDLELPNEVRRMLQQLDDLDRQ------RRKPIFT 1308
            :....::.....:.:|..|          |.|..|..|...:..:|.:.:.|      :.|.:..
  Rat   500 AARAKLEQAESTIRELQHHRHWHKCSSTYNEDFVLQLEKELVQARLSEAESQCALKEMQDKVLDI 564

  Fly  1309 ERKIGKSVSVNSHLGFPLKVLEELTERDELGSPQKQKKEKTPFFEQLRQQ-------QQQHRLNG 1366
            |:|.......|:        :..|.|  ||.:.:.::.|.....::||||       .|:|....
  Rat   565 EKKNNSFPDENN--------IARLQE--ELIAVKLREAEAIMGLKELRQQVRDLEEHWQRHVART 619

  Fly  1367 GGQSSNVGESGSPTPPSRPNRLLDNASARTVMQVKLDELKLPE 1409
            .|:..:        ||.|        :|.:.:|.:|..::|.|
  Rat   620 SGRWKD--------PPKR--------NAVSELQGELMSIRLRE 646

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
plx	NP_001163511.1	PTB_TBC1D1_like	301..601	CDD:269967
		DUF3350	835..880	CDD:288663	9/45 (20%)
		TBC	933..1152	CDD:214540	76/218 (35%)
		RILP-like	<1176..1267	CDD:304877	22/113 (19%)
Evi5	XP_006250585.2	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4436
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810