DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab23 and rab23

DIOPT Version :9

Sequence 1:	NP_649574.1	Gene:	Rab23 / 40701	FlyBaseID:	FBgn0037364	Length:	268	Species:	Drosophila melanogaster
Sequence 2:	NP_001018579.1	Gene:	rab23 / 553778	ZFINID:	ZDB-GENE-050522-328	Length:	237	Species:	Danio rerio

Alignment Length:	252	Identity:	142/252 - (56%)
Similarity:	168/252 - (66%)	Gaps:	27/252 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 MREDDIELAIKVVIVGNGGVGKSSMIQRYCKGIFTKDYKKTIGVDFLERQIEIDGEDVRIMLWDT 93
            |.|:|:|:|||||:||||.||||||||||||||||||||||||||||||||.::|||||:|||||
Zfish     1 MLEEDMEVAIKVVVVGNGAVGKSSMIQRYCKGIFTKDYKKTIGVDFLERQIIVNGEDVRLMLWDT 65

  Fly    94 AGQEEFDCITKAYYRGAQASVLVFSTTDRASFDAIKDWKRKVENECNEIPTVIVQNKIDLIEQAV 158
            |||||||.|||||||||||.|||||||||.||:||..||.|||.|..:||||:|||||||::..|
Zfish    66 AGQEEFDAITKAYYRGAQACVLVFSTTDRESFEAISSWKEKVEMEVGDIPTVLVQNKIDLLDDTV 130

  Fly   159 VTADEVETLAKLLNCRLIRTSVKEDINVASVFRYLATK-CHQLMTQSYDQV-----------AGN 211
            :..:|.|.|||.|..|..|||||||:||..||:|||.| ..:|..||.::.           ..|
Zfish   131 IKNEEAEGLAKRLKLRFYRTSVKEDLNVNEVFKYLADKYLQRLKQQSAEETDIIHTSSNKIGVFN 195

  Fly   212 QQNSSHPPYSSTPTISAFSPTFTKSSSGTIVLRPAKKGHGSSVARKRKIVLKKCGIL 268
            ...|.||..:|:..          :....:.|||.|:.     .:|.|.....|.:|
Zfish   196 TTGSGHPNQNSSDL----------NGREIVNLRPNKQR-----TKKTKNPFGSCRLL 237

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab23	NP_649574.1	Ras	50..199	CDD:278499	111/149 (74%)
Rab23	NP_649574.1	Rab23_like	50..197	CDD:133306	111/147 (76%)
rab23	NP_001018579.1	RAB	22..172	CDD:197555	111/149 (74%)
rab23	NP_001018579.1	Rab23_like	22..169	CDD:133306	110/146 (75%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170589258
Domainoid	1	1.000	242	1.000	Domainoid score	I2180
eggNOG	1	0.900	-	-		E1_KOG4252
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H7503
Inparanoid	1	1.050	257	1.000	Inparanoid score	I3141
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1340129at2759
OrthoFinder	1	1.000	-	-		FOG0008376
OrthoInspector	1	1.000	-	-		oto40011
orthoMCL	1	0.900	-	-		OOG6_105709
Panther	1	1.100	-	-	LDO	PTHR24073
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5549
SonicParanoid	1	1.000	-	-		X6363
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.790