DRSC/TRiP Functional Genomics Resources

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Protein Alignment Rab23 and RAB24

DIOPT Version :9

Sequence 1:NP_649574.1 Gene:Rab23 / 40701 FlyBaseID:FBgn0037364 Length:268 Species:Drosophila melanogaster
Sequence 2:NP_001026847.1 Gene:RAB24 / 53917 HGNCID:9765 Length:203 Species:Homo sapiens


Alignment Length:196 Identity:59/196 - (30%)
Similarity:101/196 - (51%) Gaps:20/196 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly    38 IKVVIVGNGGVGKSSMIQRYCKGIF-TKDYKKTIGVDFLERQIEIDGEDVRIMLWDTAGQEEFDC 101
            :|||::|...|||:|:::||....| ...|:.|||..|:.:.:.:....|.:.:|||||.|.::.
Human     8 VKVVMLGKEYVGKTSLVERYVHDRFLVGPYQNTIGAAFVAKVMSVGDRTVTLGIWDTAGSERYEA 72

  Fly   102 ITKAYYRGAQASVLVFSTTDRASFDAIKDW---KRKVENECNEIPTVIVQNKIDLIEQ----AVV 159
            :::.|||||:|:::.:..||.:||:..|.|   .|.:|..|.   ..:...|.||:|:    ..|
Human    73 MSRIYYRGAKAAIVCYDLTDSSSFERAKFWVKELRSLEEGCQ---IYLCGTKSDLLEEDRRRRRV 134

  Fly   160 TADEVETLAKLLNCRLIRTSVKEDINVASVFR-----YLATKCHQLMTQSYDQVAGNQQNSSHPP 219
            ...:|:..|..:..:|..||.|...:|..:|:     |::....|:||:......|.:.|    |
Human   135 DFHDVQDYADNIKAQLFETSSKTGQSVDELFQKVAEDYVSVAAFQVMTEDKGVDLGQKPN----P 195

  Fly   220 Y 220
            |
Human   196 Y 196

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Rab23NP_649574.1 Ras 50..199 CDD:278499 46/161 (29%)
Rab23_like 50..197 CDD:133306 46/159 (29%)
RAB24NP_001026847.1 Rab24 8..201 CDD:133318 59/196 (30%)
Effector region. /evidence=ECO:0000250 37..45 4/7 (57%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1340129at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.010

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