Protein Alignment Rab23 and RAB19

DIOPT Version :10

• Sequence 1: NP_649574.1
• Gene: Rab23 / 40701
• FlyBaseID: FBgn0037364
• Length: 268
• Species: Drosophila melanogaster
• Sequence 2: NP_001008749.2
• Gene: RAB19 / 401409
• HGNCID: 19982
• Length: 217
• Species: Homo sapiens
• Alignment Length: 210
• Identity: 68/210 - (32%)
• Similarity: 123/210 - (58%)
• Gaps: 18/210 - (8%)

  Fly    31 EDDIELAIKVVIVGNGGVGKSSMIQRYCKGIFTKDYKKTIGVDFLERQIEIDGEDVRIMLWDTAG 95
            :::.:...|::::|:..|||:.::|.:..|::|:..:.||||||..|.::|||:.|::.:|||||
Human    11 DENFDYLFKIILIGDSNVGKTCVVQHFKSGVYTETQQNTIGVDFTVRSLDIDGKKVKMQVWDTAG 75

  Fly    96 QEEFDCITKAYYRGAQASVLVFSTTDRASFDAIKDWKRKVEN-ECNEIPTVIVQNKIDLIEQAVV 159
            ||.|..||::|||.|.|:::.:..|.|::|::|..|..::|. ....:..:::.||.||.|:..|
Human    76 QERFRTITQSYYRSAHAAIIAYDLTRRSTFESIPHWIHEIEKYGAANVVIMLIGNKCDLWEKRHV 140

  Fly   160 TADEVETLAK---LLNCRLIRTSVKEDINVASVFRYLATKCHQLMTQS----YDQVAGNQQNSSH 217
            ..::..|||:   ||  .::.||.||..|:..||..:|   .:|:.::    |.:.|.|..
Human   141 LFEDACTLAEKYGLL--AVLETSAKESKNIEEVFVLMA---KELIARNSLHLYGESALNGL---- 196

  Fly   218 PPYSSTPTISAFSPT 232
             |..|:|.:.|..|:
Human   197 -PLDSSPVLMAQGPS 210

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab23	NP_649574.1	Rab23_like	50..197	CDD:133306	55/150 (37%)
RAB19	NP_001008749.2	Rab19	15..179	CDD:133267	59/168 (35%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:Q9H0U4	39..54		6/14 (43%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:Q9H0U4	74..89		9/14 (64%)