DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab23 and Rab23

DIOPT Version :9

Sequence 1:	NP_649574.1	Gene:	Rab23 / 40701	FlyBaseID:	FBgn0037364	Length:	268	Species:	Drosophila melanogaster
Sequence 2:	NP_001153201.1	Gene:	Rab23 / 19335	MGIID:	99833	Length:	237	Species:	Mus musculus

Alignment Length:	229	Identity:	135/229 - (58%)
Similarity:	168/229 - (73%)	Gaps:	16/229 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 MREDDIELAIKVVIVGNGGVGKSSMIQRYCKGIFTKDYKKTIGVDFLERQIEIDGEDVRIMLWDT 93
            |.|:|:|:|||:|:||||.||||||||||||||||||||||||||||||||:::.||||:|||||
Mouse     1 MLEEDMEVAIKMVVVGNGAVGKSSMIQRYCKGIFTKDYKKTIGVDFLERQIQVNDEDVRLMLWDT 65

  Fly    94 AGQEEFDCITKAYYRGAQASVLVFSTTDRASFDAIKDWKRKVENECNEIPTVIVQNKIDLIEQAV 158
            |||||||.|||||||||||.|||||||||.||:||..|:.||..|..:|||.:|||||||::.:.
Mouse    66 AGQEEFDAITKAYYRGAQACVLVFSTTDRESFEAISSWREKVVAEVGDIPTALVQNKIDLLDDSC 130

  Fly   159 VTADEVETLAKLLNCRLIRTSVKEDINVASVFRYLATKCHQLMTQSYDQVAGNQQNSSHPPYSST 223
            :..:|.|.|||.|..|..|||||||:||:.||:|||.|..|.:.|   |:..:.:.:    :||:
Mouse   131 IKNEEAEGLAKRLKLRFYRTSVKEDLNVSEVFKYLAEKHLQKLKQ---QITEDPEQT----HSSS 188

  Fly   224 PTISAFSPTF-----TKSSS---GTIV-LRPAKK 248
            ..|..|:.:.     ..|||   |.:: |||.|:
Mouse   189 NKIGVFNASVRSHLGQNSSSLNGGDVINLRPNKQ 222

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab23	NP_649574.1	Ras	50..199	CDD:278499	106/148 (72%)
Rab23	NP_649574.1	Rab23_like	50..197	CDD:133306	105/146 (72%)
Rab23	NP_001153201.1	Rab23_like	10..169	CDD:133306	114/158 (72%)
		Effector region. /evidence=ECO:0000250	38..46		7/7 (100%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	204..237		8/26 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167844356
Domainoid	1	1.000	235	1.000	Domainoid score	I2359
eggNOG	1	0.900	-	-		E1_KOG4252
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H7503
Inparanoid	1	1.050	250	1.000	Inparanoid score	I3217
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1340129at2759
OrthoFinder	1	1.000	-	-		FOG0008376
OrthoInspector	1	1.000	-	-		oto92661
orthoMCL	1	0.900	-	-		OOG6_105709
Panther	1	1.100	-	-	LDO	PTHR24073
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5549
SonicParanoid	1	1.000	-	-		X6363
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.790