Protein Alignment Atg17 and atg11

DIOPT Version :10

• Sequence 1: NP_649573.2
• Gene: Atg17 / 40700
• FlyBaseID: FBgn0037363
• Length: 1357
• Species: Drosophila melanogaster
• Sequence 2: NP_593855.1
• Gene: atg11 / 2541735
• PomBaseID: SPAC7D4.04
• Length: 926
• Species: Schizosaccharomyces pombe
• Alignment Length: 1106
• Identity: 198/1106 - (17%)
• Similarity: 375/1106 - (33%)
• Gaps: 385/1106 - (34%)

  Fly     1 MMLYVFHVDVGRMLSFDMNVALQPVEHLKETIQKLHNIPAANIVLLVSGGEMLTHSTQVSCYSAG 65
            ::.::..:::|  ||.:..:.|.....|.||:..    ..:::|:.|....:||
pombe    26 LVAWIMELNIG--LSDEAKLLLPNGMSLNETVLN----SESDVVIYVLDQNLLT----------- 73

  Fly    66 TDTNPIYMFLTGDERLP--PTIYNSDADNELRRQVEESHRLPPALETVRQRAQLAQHMRELARKE 128
                    |....:::|  |::......|.|...:.:|.. ....:.:.:...|...:.|.:.|.
pombe    74 --------FTYDGDKIPSIPSLKGQPISNVLTGIIADSSS-DQWKDKISKCLSLLSDILESSSKI 129

  Fly   129 EDQCERLVHEQ-------------HLQQQGWSAVVANMEDLTNEFCDRFQNFCSFFDRHLQKRES 180
            .:|.. :.|::             :||::     .:.|:||...|.:|..            |.|
pombe   130 HNQLS-VCHDEYSTSIVSPEVAMNYLQRR-----QSGMKDLLFVFYERLD------------RVS 176

  Fly   181 FLELLRNF---PDDLKQLGRIPILPDLMSLAEADFHGFDELLDNDDVFTAQQQPTPQQQALTESS 242
            ..:||.:|   |     .|.:||.|  :.:...::...|..|::.....|:.|...||.....:|
pombe   177 VSDLLHDFLALP-----TGSLPITP--LKILSTNWTKLDSWLNSISARYAEAQKRVQQCIGAANS 234

  Fly   243 QADSPNKK---LKMGDEVETESGEQTERGVQTLTSSSSLARRPNLNLLQWISSKGNHRALQLMSD 304
            ...||.|:   :|.||:....        ::::...::       |:||
pombe   235 IIVSPFKEVPSIKEGDDAYYH--------LRSVAQDAA-------NILQ---------------- 268

  Fly   305 ECIQGLDVFSVEIYEKLKEEVNQIIKLANQADVKEIKGLGDRLCKLEEFKFRIKKMVQEQKEQAL 369
                                  :|:|:.:.:...:||.           |...:..:.:..|:
pombe   269 ----------------------EILKIESTSTTSQIKP-----------KCNYETEITDCMEK-- 298

  Fly   370 ALQQNEARAQNLRDNSV--LPDLCLSHRSQLQVMLDNHIKIREYCRCIANSKDELGWNLHTRLRR 432
             ||.|.:..::.|.:|:  |....||.   .:|.| .:..:.||.|.||...|.
pombe   299 -LQSNLSELKSSRKSSLISLKSFWLSF---YKVSL-RYDALYEYLRQIAEELDR----------- 347

  Fly   433 IVWIENGMSEFDNRLLFNHRCLRRAERHICIIEQIHRAPSTYVSAVAEVVRRKIFSDEFRQWATR 497
                    |:|                   ::.|.....|.|:..:.|.:||       .:|...
pombe   348 --------SKF-------------------VLSQSRNIFSLYIDILMEALRR-------TEWQES 378

  Fly   498 LSADFDRI----HSEELSRRRDFNASFEGHFLNILFPGMGDMPPAFANEHPLSFDTRLPSLSRSD 558
            .:...|..    ..:|||.|:    |:..||.|:||           |...|.:   ||.|:|.:
pombe   379 YNVSHDSSLPLDQEKELSLRK----SWLSHFSNLLF-----------NHGQLKY---LPVLTRDE 425

  Fly   559 MELLSSQLPELAGQLQLPDMKPVIDFFALRSDKNVEPDQEQERDIPLMAPRLAEL-----QAQAA 618
               :|:.|                        .|::.....:....:::.||:|.     ..:.|
pombe   426 ---ISNYL------------------------LNIQAHPNYQTFHQMLSNRLSEYLGFPGSPREA 463

  Fly   619 ASDCETDTETEFEKLST-TSKCVATSISTSLVEQVA---------------------QSTATEDL 661
            .|:......:..|||:. .::|  .::...|..|..                     ||.:::..
pombe   464 VSNTVQANNSLHEKLAMYQNRC--NNLEAMLSHQNGFNYNINNDGLSPNAPHPPINEQSNSSQPF 526

  Fly   662 LMLSAGTLTEENAGSFEKMRSDMESMTKLARACLAEARSNVGVFRS--DVANYQDE-LQSELHLL 723
            ..:|...:      ....:|......|....:.:...:..|...|:  |:.|.::| |..||...
pombe   527 YRVSPSIV------PLNVIRKLTNRKTSFTDSHILRLQDEVNQLRNELDLVNKRNEDLLIELQGK 585

  Fly   724 RDKCNVLKMMCEEREQK---LQEKLDEMSLKLQLAEQEKQAAVAQAREQL------------IHE 773
            .:|...|:...||..||   |||:|.  |.:..|.:.|...|..|:.|::            :.|
pombe   586 EEKIQYLETENEEVLQKYENLQEELS--STRKLLTKNEAAVAEQQSNEEMHSNEPNILNLYSVFE 648

  Fly   774 HKTE-LESLRCRFKL-MTSMERSPSDSSLEKIERPTSSASVVSANAGVDIDHLLAQQRQELLAQR 836
            .|.: |:.|...||| :||:::....::|.|.                      |:..|.::.:|
pombe   649 GKVDSLQELYNAFKLQLTSLKQKGEYATLAKD----------------------AEAVQHIIEER 691

  Fly   837 ERAISEAVDSERSLWQSRLLPLNSESVMANVGILKDMLADKERQLDQLREQNKILTQETYQLKTR 901
            :.|::|..|         ||.|:                      :..:||.|||||:.|.:..|
pombe   692 DYALAEKAD---------LLKLS----------------------ENRKEQCKILTQKLYTIVFR 725

  Fly   902 L--------EMIT-------NE-DGNSWLKEK-IDYLNKDKCRLEEELSQEKSRR-QEMESSVAA 948
            .        |.:|       || ||::.:.:: |::.:||...|.....::..|. ||..:.:::
pombe   726 CNELQSVLRECVTQPGFDSDNERDGHASIPDRQIEFNSKDLQYLYWMDGEDADRNFQEFLNRMSS 790

  Fly   949 MRSSAYDLNVGGPLTRSKS------------------GVSSSHRSIALEGCARGDLVFVVWSMRH 995
            :...::...|...||::.:                  .:..|...::|....:|.||..:.:.|.
pombe   791 LDFDSFHNFVVSVLTQAHNHELRWKREFQSNRDKALKAILDSQSKVSLRNFKQGSLVLFLPTRRT 855

  Fly   996 A 996
            |
pombe   856 A 856

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atg17	NP_649573.2	Ubl_RB1CC1	2..74	CDD:340580	11/71 (15%)
		ATG17_like	107..525	CDD:427715	76/442 (17%)
		SMC_N	<678..>958	CDD:481474	68/317 (21%)
		ATG11	943..1082	CDD:463063	10/72 (14%)
		DUF5585	<1077..>1324	CDD:465521
atg11	NP_593855.1	ATG17_like	111..409	CDD:427715	78/442 (18%)
		CCDC158	254..>845	CDD:464943	141/814 (17%)
		Atg11_middle	511..589	CDD:437529	13/83 (16%)
		ATG11	797..922	CDD:463063	10/60 (17%)