Protein Alignment Atg17 and rb1cc1

DIOPT Version :10

• Sequence 1: NP_649573.2
• Gene: Atg17 / 40700
• FlyBaseID: FBgn0037363
• Length: 1357
• Species: Drosophila melanogaster
• Sequence 2: XP_009300473.1
• Gene: rb1cc1 / 100332174
• ZFINID: ZDB-GENE-130206-1
• Length: 1622
• Species: Danio rerio
• Alignment Length: 1664
• Identity: 384/1664 - (23%)
• Similarity: 589/1664 - (35%)
• Gaps: 629/1664 - (37%)

  Fly     1 MMLYVFHVDVGRMLSFDMNVALQPVEHLKETIQKLHNIPAANIVLLVSGGEMLTHSTQVSCYSAG 65
            |.||||.|:.|..|:||..:|:|.|..||..||..:.|...:.||:|:|||.:....:|..||||
Zfish     1 MKLYVFQVNNGSTLTFDTELAVQTVLDLKHAIQAKYKIAIQHQVLVVNGGECMVAERRVCSYSAG 65

  Fly    66 TDTNPIYMF----LTGDE--RLPPTIYNSDADNELRRQVEESHRLPPALETVRQRAQLAQHMREL 124
            ||||||::|    :..|.  .:|.|.:.  .:||:..:||||..:|....||..|.|||..|.|:
Zfish    66 TDTNPIFLFNKEMILCDRAPTIPKTTFT--IENEMELKVEESLMMPAVFHTVASRTQLALEMFEV 128

  Fly   125 ARKEEDQCERLVHEQHLQQQGWSAVVANMEDLTNEFCDRFQNFCSFFDRHLQKRESFLELLRNFP 189
            |:|....||||||::|||.|||:|::||::|.|..:......|.:.:..:.|..|.....|....
Zfish   129 AKKLCSFCERLVHDEHLQHQGWAAIMANLDDCTLSYQKLLLKFDTAYTNYQQDFEDIKLKLTKLG 193

  Fly   190 DDLKQLGRIPILPDLMSLAEADFHGFDELL------------DNDDV------------------ 224
            ..:..:.:||:|..|..      |.:.|.|            ::||:
Zfish   194 IAVSVMAKIPLLECLTR------HSYRESLEKSSSPRPRIIDEDDDIEDEEIAEASTRSPALCPP 252

  Fly   225 --FTAQQQPTPQQQALTESSQA-DSPNKKLKMGDEVETESGEQTERGVQTLTSSSSLARRPNLNL 286
              ...|:.|:|    ::.|||| .||..:||....:: |:.::.|...:.:...|.     |:.|
Zfish   253 DNLKNQKSPSP----VSASSQASSSPQDRLKSSSSLK-EALQEEEESPERMAMPSF-----NVTL 307

  Fly   287 LQWISSKGNHRALQLMSDECIQGLDVFSVEIYEKLKEEVNQ-IIKLANQADVKEIKGLGDRLCKL 350
            |.||:.:.....::.:..:|...::.....|.:....|..: |.||.|| ::|.||||.|||..|
Zfish   308 LDWINVQDRPNDVESVVRKCFDSINRLDPRIIQPFLTECRETITKLDNQ-NMKAIKGLEDRLYAL 371

  Fly   351 EEFKFRIKKMVQEQKEQALALQQNEARAQNLRDNSVLPDLCLSHRSQLQVMLDNHIKIREYCRCI 415
            ::.....||:|.||||.|.....|:.||:||:|.||||||||||.:||.:||.||.|:.:..:..
Zfish   372 DQMIASCKKLVNEQKELAQGFLANQKRAENLKDTSVLPDLCLSHANQLMIMLTNHRKLLDIKQKC 436

  Fly   416 ANSKDELGWNLHTRLRRIVWIENGMSEFDNRLLFNHRCLRRAERHICIIEQIHRAPSTYVSAVAE 480
            ..:|.||..||..||:...::.....:...:|....|.|......:.::|.:...|..|..||.|
Zfish   437 TTAKQELANNLQVRLKWCCYVMLHADQDGEKLQALLRLLTELLERVRVVEALSTVPQMYCLAVVE 501

  Fly   481 VVRRKIFSDEFRQWATRLSADFDRIHSEELSRRRDFNASFEGHFL-NILFPGMGDMPP-AFANEH 543
            |||||:|...:||||..|..|...::..|..:|..|...|...|| |.||.|:...|| :|....
Zfish   502 VVRRKMFIGHYRQWANALVKDGKNLYEAEKVKRETFGKLFRKSFLRNRLFRGLDSWPPSSFCTRK 566

  Fly   544 PLSFDTRLPSLSRSDMELLSSQLP-ELAGQLQLP---DMKPV----------------IDFFA-- 586
            |..||..||.:|.||::.|.|..| |:...|::|   |.:|:                :|..:
Zfish   567 PRRFDFELPDISLSDLQYLKSCCPSEVQPYLRVPTLCDFEPLNQHVEVLHQLVQAAQSVDEMSQT 631

  Fly   587 ----LRSDKNVEPDQEQERDIPLMAPR--------------LAELQAQAAASDCE---------- 623
                |...|| ...|..:|...| .||              |:.|..:  |.||:
Zfish   632 ITDLLNEQKN-SYSQSAQRSTAL-TPRSESAIEITSTSTKTLSTLSLK--APDCQPLALPGPLED 692

  Fly   624 -----TDTET-EFEKLS------------------------------------------------ 634
                 .|.:| :||.:.
Zfish   693 LSPDSIDAQTFDFETIGHPSMDPVLQQGSLDLDSLAESPESDFMSAVNEFVIEENLLSPNPISDP 757

  Fly   635 TTSKCVATSISTSLVEQV----AQSTATED-------LLMLSAG---TLTEENAGSFEKMRSDME 685
            |:.:.:..|:.:|::..:    .|.|.|.:       .:.|||.   :..||:..:..|::.|:.
Zfish   758 TSPEMMVESLYSSVINAIDSKRIQDTTTLEKENSKIAAIKLSADRYRSAAEESQNNLRKVKEDLY 822

  Fly   686 SMTKLARACLAEAR-----------------SNVGVFRSD--------------------VANYQ 713
            ....|.   |.|.|                 |||.....:                    :....
Zfish   823 HFRGLV---LKEQRDFGFALKTMTTEVHNALSNVSYSHEEELKETQQTHLQSLKEDHEKQIRTLT 884

  Fly   714 DELQSELHLLRDKCNVLKMMCE-----------------ERE--------------QKLQEKL-- 745
            :||:....:::|   |.:.|.|                 |||              |.|:||:
Zfish   885 EELEGNQKIVKD---VQRAMLELEGLVERKEKEIYQLESERERSTQELQDLHKQAVQNLEEKILK 946

  Fly   746 ------------DEMS-------------------------------LKLQLAEQ---------- 757
                        ||::                               |:.:|.:|
Zfish   947 QSEELKSALLSKDELAGQLEKLHFEIEHGQQKIRQEMKNAEKVHLQELETRLNQQHEAELQTFRL 1011

  Fly   758 EKQAAVAQARE-------QLIHEHK-----------------TELESLRCRFKL-MTSMERSPSD 797
            ||::|:.:..:       .|:..|.                 |||...||:.:: |...|....|
Zfish  1012 EKESALDKLVQDNLVKLRDLMDSHSAELKERDGRSKDMDARITELADARCKLEVEMALKEAEMED 1076

  Fly   798 SSLEKIERPTSSASVVSANAG-------VDIDHL--------------LAQQRQELLAQRERAIS 841
            ..|:..|..::...|:.|...       :.||.|              ||:.|..:..:::..||
Zfish  1077 MRLQYEEAKSTQEEVLKAEFATQTSTLKMQIDTLSLQLHQKNEEYEVGLAELRALMRLEKDHCIS 1141

  Fly   842 EAVD------------------------------------------------------------- 845
            |.||
Zfish  1142 ELVDRHEEESTLLRHEFSALKQKSQDVEKDCEERVLKIERDYKDRVDALQREKVEEQRAFQEKED 1206

  Fly   846 ----------SERSLWQSR--------LLPLNSESVMANVGILKDMLAD---------------- 876
                      :|.||...|        ||.:..|...|....|::.|.|
Zfish  1207 DLRTVIGDLQAENSLLSGRLEQERVEALLRVQEEKEEAVKAALQEALRDIQLQKEETETRLLGQI 1271

  Fly   877 -------KERQ-----------------------LD---------------QLREQNKILTQETY 896
                   |:||                       ||               :|.|:.|  .:|..
Zfish  1272 ELLEKQLKDRQSTDTVASSAEQTEAGVQAETAVSLDSGQWTEERASLLAKLELLERTK--NEEMQ 1334

  Fly   897 QLKTRL--------------EMITNEDGNSWLKEK--------------IDYLNKD-------KC 926
            .|||.|              |.:..|...|.|.||              |:.|::|       |.
Zfish  1335 NLKTSLIAEQQTNFNTVLTREKLKKEQIISDLTEKLKNVMQQQEKDKGLIETLSEDRASILQEKK 1399

  Fly   927 RLEEELSQEKSR--------------------------------------------------RQE 941
            :|||||::.:|.                                                  .:.
Zfish  1400 QLEEELNRLRSTVLVSSSFFPPNPIVPVVAEAHGACGPAQVDALSPSFPDPERLISMAAFRDEER 1464

  Fly   942 MESSVAAMRSSAYDLN---------------------------VGGPLTRSKSGVSSSH-RSIAL 978
            :||:|.|...:.:..|                           ....:::|.|.|||.| ..||:
Zfish  1465 VESAVEASMMTVHSDNSMLSEEKQRILILERTLHMKEEENKRLSQRLMSQSMSSVSSRHSEKIAI 1529

  Fly   979 EGCARGDLVFVVWSMRHAQFMVVQDSLTLYFVHADSLASLQLTAPTSPTPSLDPSQTVVDINQIP 1043
            .....||||.::...||..:::.....||||:|::||.:|.|...|..|             :.|
Zfish  1530 RDFQVGDLVLIILDERHDNYVLFTVGPTLYFLHSESLTALDLKPATGAT-------------RRP 1581

  Fly  1044 LPYYAIGRVIDKEYCQARKDDNRYRVSRGSKFYRIKLAP 1082
               :.:|:|::||||||:|..||::|..|:||||:|..|
Zfish  1582 ---WVLGKVMEKEYCQAKKAQNRFKVPLGTKFYRVKAVP 1617

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atg17	NP_649573.2	Ubl_RB1CC1	2..74	CDD:340580	34/71 (48%)
		ATG17_like	107..525	CDD:427715	139/451 (31%)
		SMC_N	<678..>958	CDD:481474	100/700 (14%)
		ATG11	943..1082	CDD:463063	49/166 (30%)
		DUF5585	<1077..>1324	CDD:465521	3/6 (50%)
rb1cc1	XP_009300473.1	Ubl_RB1CC1	2..76	CDD:340580	35/73 (48%)
		ATG17_like	<304..537	CDD:427715	83/233 (36%)
		Smc	<858..1413	CDD:440809	86/559 (15%)
		ATG11	<1525..1617	CDD:463063	38/107 (36%)