Protein Alignment Wdr33 and Wdr33

DIOPT Version :10

• Sequence 1: NP_730982.1
• Gene: Wdr33 / 40698
• FlyBaseID: FBgn0046222
• Length: 807
• Species: Drosophila melanogaster
• Sequence 2: XP_063133449.1
• Gene: Wdr33 / 307524
• RGDID: 1309230
• Length: 1343
• Species: Rattus norvegicus
• Alignment Length: 834
• Identity: 378/834 - (45%)
• Similarity: 478/834 - (57%)
• Gaps: 134/834 - (16%)

  Fly    17 LATNFTSLPPPNMGGQHYRHYHPHHGSNKHGYNQFKPFMPGGFQRPFGMSQDDFDGKRLRKSVMR 81
            :||...| ||.......::|..|.....|      :|    .|.:...|.|..|||||:||:|.|
  Rat     1 MATEIGS-PPRFFHMPRFQHQAPRQLFYK------RP----DFAQQQAMQQLTFDGKRMRKAVNR 54

  Fly    82 KTVDYNASIIKALENRLYQRDYRDRLALQPDSIYVPHMLPPSAYLDNPSNAVTTRFVKTATNKMR 146
            ||:|||.|:||.||||::|||.||..|:|||:.|...::||...|:||.|||||:||:|:|||::
  Rat    55 KTIDYNPSVIKYLENRIWQRDQRDMRAIQPDAGYYNDLVPPIGMLNNPMNAVTTKFVRTSTNKVK 119

  Fly   147 CPIFTLAWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDISVRTMVWSHNDSWMVTGDHGGY 211
            ||:|.:.|||||||||||||||||||||||||||||||||||..||.|.|||||.||:|.|||||
  Rat   120 CPVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTADHGGY 184

  Fly   212 VKYWQSNMNNVKMYQAHKEAIRGISFSPTDSKFVSGSDDGTLRIWDFMRCQEERVLRGHGADVKC 276
            |||||||||||||:||||||||..||||||:||.:.|||||:|||||:||.|||:||||||||||
  Rat   185 VKYWQSNMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHEERILRGHGADVKC 249

  Fly   277 VHWHPQKGMIVSGSKDNQQPIKIWDPKSGIALATLHAHKSTVMDLKWNDNGNWLVTASRDHLLKL 341
            |.|||.||::||||||:|||||.||||:|.:||||||||:|||::|.|.|||||:|||||||.||
  Rat   250 VDWHPTKGLVVSGSKDSQQPIKFWDPKTGQSLATLHAHKNTVMEVKLNLNGNWLLTASRDHLCKL 314

  Fly   342 FDIRNLREEVQVFRGHKKEASSVSWHPIHEGLFCSGGSDGSILFWNVGTDKEIGCVETAHDSIVW 406
            ||||||:||:||||||||||::|:|||:|||||.|||||||:|||:||.:||:|.:|.||:.::|
  Rat   315 FDIRNLKEELQVFRGHKKEATAVAWHPVHEGLFASGGSDGSLLFWHVGVEKEVGGMEMAHEGMIW 379

  Fly   407 TLAWHPLGHILCSGSNDHTIKFWTRNRPGDLMRDKYNLNTLPASLAALDECEYDD------AIIP 465
            :||||||||||||||||||.||||||||||.|||:||||.||.  .:.|..||||      |:||
  Rat   380 SLAWHPLGHILCSGSNDHTSKFWTRNRPGDKMRDRYNLNLLPG--MSEDGVEYDDLEPNSLAVIP 442

  Fly   466 GMGPEDRVEFT---ESLTADKG-----FIPGLDLDPSKAINDRDR---EKKVPYSKPIPRNFQVN 519
            |||..::::..   |.:..|:.     .|||||....:.:....:   :|||||:||||..||..
  Rat   443 GMGIPEQLKLAMEQEQMGKDESNDIEMTIPGLDWGMEEVMQKDQKKVPQKKVPYAKPIPAQFQQA 507

  Fly   520 WAG---PRRADDPSVLSIHEELAAREAKDT---------TNGLNHQQISENTMEGILASGMLNGL 572
            |..   |..|.:..:....|::...|.|.|         |....:.|:.|......||....:.:
  Rat   508 WMQNKVPIPAPNEVLNDRKEDIKLEEKKKTQAEIEQEMATLQYTNPQLLEQLKIERLAQKQADQI 572

  Fly   573 DPQTIVGV---------------LVYNRFIRVHPDSRLMAAIRQGAEFLNKYIDAGKLEELNDVV 622
            .|....|.               .:...|.:.||..::....:.|
  Rat   573 QPPPSSGTPLLGPQPFSGQGPMSQIPQGFQQPHPSQQMPLVAQMG-------------------- 617

  Fly   623 PVRDRSRSVSPTVEARGEMVSPPTKKSRFEPRQHNAQLVCVRELMQCKKPFLQSLVAAKAQQPNT 687
            |...:.:..:|..:.:.....||..:....|                     |..:..:..|...
  Rat   618 PPGPQGQFRAPGPQGQMGPQGPPLHQGGGGP---------------------QGFMGPQGPQGPP 661

  Fly   688 EFVDEPPLEQRDRDREREGDRDRERERARERERDQSG-----GRPNPWASNAPWSN---NGNPGG 744
            :.:..|              :|....:..:|.....|     |.|.|..|:.|..:   .|.||.
  Rat   662 QGLPRP--------------QDMHGPQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGP 712

  Fly   745 NGN-GSNG-------FSNNGAESFNDRDRGGGGQRRRRGINNSGPGNGGGSGGG 790
            .|: |..|       ....|...    .:|..|....||:  .||.:..|..||
  Rat   713 QGHIGPQGPPAPQGHMGPQGPPG----TQGMQGPPGPRGM--QGPPHPHGIQGG 760

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wdr33	NP_730982.1	WD40	146..429	CDD:238121	222/282 (79%)
		WD40 repeat	149..186	CDD:293791	32/36 (89%)
		WD40 repeat	192..227	CDD:293791	28/34 (82%)
		WD40 repeat	232..268	CDD:293791	25/35 (71%)
		WD40 repeat	275..312	CDD:293791	27/36 (75%)
		WD40 repeat	318..355	CDD:293791	28/36 (78%)
		WD40 repeat	362..398	CDD:293791	24/35 (69%)
		WD40 repeat	405..429	CDD:293791	20/23 (87%)
Wdr33	XP_063133449.1	None