Protein Alignment CG2182 and GGNBP2

DIOPT Version :9

• Sequence 1: NP_649570.1
• Gene: CG2182 / 40697
• FlyBaseID: FBgn0037360
• Length: 671
• Species: Drosophila melanogaster
• Sequence 2: XP_005257746.1
• Gene: GGNBP2 / 79893
• HGNCID: 19357
• Length: 699
• Species: Homo sapiens
• Alignment Length: 636
• Identity: 219/636 - (34%)
• Similarity: 331/636 - (52%)
• Gaps: 88/636 - (13%)

  Fly     1 MARLTKVYNTDDDDSGYVGRRNLPLVAGDKLMMLMDLNSKGLVIDSPLIRGRELEEFSRKFKLLT 65
            ||||..|....:::..: .||.:||...|.|.|:|:.....|.:|.....|.:|::|.::..:|.
Human     1 MARLVAVCRDGEEEFPF-ERRQIPLYIDDTLTMVMEFPDNVLNLDGHQNNGAQLKQFIQRHGMLK 64

  Fly    66 EAERRQSLEIDSASFMEVLNQCVQCVGCRRRVERLFHQLTETGHRTLDPLELRPTATLGIVEEKL 130
            :.:...::.:.|...:..|:|.|.||||||.|||||.||.|:|:..|:||.:.|...|.:....:
Human    65 QQDLSIAMVVTSREVLSALSQLVPCVGCRRSVERLFSQLVESGNPALEPLTVGPKGVLSVTRSCM 129

  Fly   131 KTPQALGTLLYRHHEVLNNLLD--NKLRNKTRCVLHSLDAFRAKPFSETWREVWSAMKSNCRNEL 193
            ...:.|.||.|.|...||:::|  .|.:...||.|||||..:.||....|.:||..|...||:|:
Human   130 TDAKKLYTLFYVHGSKLNDMIDAIPKSKKNKRCQLHSLDTHKPKPLGGCWMDVWELMSQECRDEV 194

  Fly   194 TIIETKELHDVLENYLKKHKFCSGCRTKIERAYKILIGEIS-SKEKGYAAQLYAHIRKCVPDQHI 257
            .:|::..|.:.||.||:||:||:.|:.|:.|||.|||||:. ||||||.|.||..:|.|..::||
Human   195 VLIDSSCLLETLETYLRKHRFCTDCKNKVLRAYNILIGELDCSKEKGYCAALYEGLRCCPHERHI 259

  Fly   258 HVTTNKIEFLDALIKRAEPEVNGSYSKLRERHAKTLEIAQEEVLTCVGMIMYERLRRIYVSLREE 322
            ||.. :.:|:..|:.|||||..|.|.: |||||||::|||||||||:|:.:||||.||:..||.|
Human   260 HVCC-ETDFIAHLLGRAEPEFAGGYER-RERHAKTIDIAQEEVLTCLGIHLYERLHRIWQKLRAE 322

  Fly   323 ERACQVLAAVGVHALCRSFDTFVEQKQGISNLELLYQEISRAERAKQIKREQKKLKKKKKKDEKK 387
            |:..|:|..:||.||.:||:..||:.||||.||.|.:|.|..||.:::|:|:|:.|:|.::..|
Human   323 EQTWQMLFYLGVDALRKSFEMTVEKVQGISRLEQLCEEFSEEERVRELKQEKKRQKRKNRRKNK- 386

  Fly   388 NLLHRQCDDTEANESDEEEEELRNEELDLEEESQMQHEELSDPGADDGIVIEAARSPEPEPELTS 452
                ..||.....::.:|:|..:.:|.|..|.|..
Human   387 ----CVCDIPTPLQTADEKEVSQEKETDFIENSSC------------------------------ 417

  Fly   453 KPTKSKPKKQSKKKKQKKAAFTKMGNQKQMQATARVQPLDADHDQLDVASCISSSIAKTVGD-KC 516
                            |....|:.||       ..|:.:..:.:    .||...|....:|. |.
Human   418 ----------------KACGSTEDGN-------TCVEVIVTNEN----TSCTCPSSGNLLGSPKI 455

  Fly   517 EECLASMPNCPCEQDVRDSGYGSDPPSHAGSRTSSAISSPEGSEVSCSDGLCNHDVHDEDSDDLL 581
            ::.|:  |:|    :..|.||.|   |..||.|.|.    |||:|:|::|:||||.|.:||   .
Human   456 KKGLS--PHC----NGSDCGYSS---SMEGSETGSR----EGSDVACTEGICNHDEHGDDS---C 504

  Fly   582 FYSHQSQLDHKFSLLQMWDDFDEYDDKDEETYYIPQEVVMAFKCHREQVQR 632
            .:..:.:.|...|.::.|.:.:|.|.|.:......:..::  ||. |.:|:
Human   505 VHHCEDKEDDGDSCVECWANSEENDTKGKNKKKKKKSKIL--KCD-EHIQK 552

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145658
Domainoid	1	1.000	315	1.000	Domainoid score	I1279
eggNOG	1	0.900	-	-		E1_28HQM
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	316	1.000	Inparanoid score	I2558
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D194712at33208
OrthoFinder	1	1.000	-	-		FOG0009393
OrthoInspector	1	1.000	-	-		oto91515
orthoMCL	1	0.900	-	-		OOG6_108334
Panther	1	1.100	-	-	LDO	PTHR13601
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4586
SonicParanoid	1	1.000	-	-		X7131
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	13	12.830