DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MED27 and mdt-27

DIOPT Version :9

Sequence 1:	NP_649569.1	Gene:	MED27 / 40696	FlyBaseID:	FBgn0037359	Length:	293	Species:	Drosophila melanogaster
Sequence 2:	NP_505386.2	Gene:	mdt-27 / 179303	WormBaseID:	WBGene00007023	Length:	440	Species:	Caenorhabditis elegans

Alignment Length:	253	Identity:	49/253 - (19%)
Similarity:	93/253 - (36%)	Gaps:	55/253 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 YSLGNTAYLAQETSQ--DRQALYPQLVNSYKWMDKVHDHSFLAFNNLNQNTLRRSYNYCSQKRQR 135
            |.|...|.|....:.  |::.||..:.:|.:.:.:..:.::..|..|.:....|:   ..:|...
Worm   173 YELNRAAALKCRYNAVFDKRPLYKAVESSIQDLRQKDESAYQLFYKLQEAMDERT---VIEKNII 234

  Fly   136 LPFSSFNNDPDHIDKLLSEINTPPHTSY-------------------------------RIFRPF 169
            ....:|..:..|..: :|.::.||...:                               ||..|.
Worm   235 AVSETFRQNAVHAPR-VSRLSVPPPLKFSKHVEDANKGVFLAMDAVMNKTRGDLTWRFKRISHPC 298

  Fly   170 GTNAVTIVTIS-------------NVMKAAIVFKGVLIEWVTVKGFDEPLEHDDLWAESRYEVFR 221
            ..|:.:::.:.             ..|||.||.|..::|.:.:.|.||.|.:.:....|:.:|:|
Worm   299 FRNSKSLIEVHYCARRPNSEKEFVPCMKAVIVLKYGILEDMIIGGEDEDLYNQEQILHSKRKVYR 363

  Fly   222 KVQDHAHSAMLHFFSPTLPDLAVKSYI---TWLNSHVKLFLEPCKRCGKFVVNGLPPT 276
            :....|...:|  .||.....|..::.   .::.|:|..|...|..|.|.:...:|||
Worm   364 EFTKSAKEIIL--CSPVTKFTAPTNFAQCNNYIQSYVNCFSTKCYYCKKHLRQFMPPT 419

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MED27	NP_649569.1	Med27	209..287	CDD:288428	17/71 (24%)
mdt-27	NP_505386.2	Med27	351..431	CDD:288428	17/71 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0007494
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000