DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment elm and chp1

DIOPT Version :9

Sequence 1:	NP_001262295.1	Gene:	elm / 40695	FlyBaseID:	FBgn0037358	Length:	189	Species:	Drosophila melanogaster
Sequence 2:	NP_956009.1	Gene:	chp1 / 325361	ZFINID:	ZDB-GENE-030131-4086	Length:	194	Species:	Danio rerio

Alignment Length:	199	Identity:	117/199 - (58%)
Similarity:	149/199 - (74%)	Gaps:	15/199 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGNKSSLFLRNEEIAQIQEETGFTPNQIERLYSRFTSLDRNDCGTLSREDLMRIPELAINPLCER 65
            ||:::|..||.|:|.:|::||||:.:||.||||||.|||:.:.|.|||||..||||||||||.:|
Zfish     1 MGSRASSLLREEDIEEIKKETGFSHSQITRLYSRFHSLDKGENGGLSREDFQRIPELAINPLGDR 65

  Fly    66 IVHSFFAESNDDRVNFRQFMNVLAHFRPLRDNKQSK------LNSREEKLKFAFKMYDLDDDGVI 124
            |:::||.| .:|:||||.||..||||||:.||:::|      ||||..||.|||::||||.|..|
Zfish    66 IINAFFPE-GEDQVNFRGFMRTLAHFRPVEDNEKNKDLTGEPLNSRTNKLLFAFRLYDLDRDDKI 129

  Fly   125 SRDELLSILHMMVGANISQDQLVSIAERTILEA----DLCCQGKISFEDFCKALDRTDVDQKMSI 185
            ||||||.:|.||||.|||.:||.|||:|||.||    |:|    |||.:|.|.|::.||:|||||
Zfish   130 SRDELLQVLRMMVGVNISDEQLGSIADRTIQEADTNGDMC----ISFNEFTKVLEKVDVEQKMSI 190

  Fly   186 RFLN 189
            |||:
Zfish   191 RFLH 194

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
elm	NP_001262295.1	FRQ1	23..173	CDD:227455	94/159 (59%)
chp1	NP_956009.1	FRQ1	1..181	CDD:227455	107/184 (58%)
chp1	NP_956009.1	EFh	113..179	CDD:238008	42/69 (61%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592178
Domainoid	1	1.000	124	1.000	Domainoid score	I5494
eggNOG	1	0.900	-	-		E2759_KOG0034
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5235
Inparanoid	1	1.050	217	1.000	Inparanoid score	I3572
OMA	1	1.010	-	-		QHG53747
OrthoDB	1	1.010	-	-		D1271942at2759
OrthoFinder	1	1.000	-	-		FOG0000640
OrthoInspector	1	1.000	-	-		oto41056
orthoMCL	1	0.900	-	-		OOG6_105864
Panther	1	1.100	-	-	LDO	PTHR46002
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3958
SonicParanoid	1	1.000	-	-		X2469
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800