DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment elm and chpf-2

DIOPT Version :9

Sequence 1:	NP_001262295.1	Gene:	elm / 40695	FlyBaseID:	FBgn0037358	Length:	189	Species:	Drosophila melanogaster
Sequence 2:	NP_503830.2	Gene:	chpf-2 / 186617	WormBaseID:	WBGene00019108	Length:	195	Species:	Caenorhabditis elegans

Alignment Length:	195	Identity:	101/195 - (51%)
Similarity:	144/195 - (73%)	Gaps:	6/195 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGNKSSLFLRNEEIAQIQEETGFTPNQIERLYSRFTSLDRNDCGTLSREDLMRIPELAINPLCER 65
            |||.:|..|.:.|:.:|.:||.|..:||.|||:||.|||:|..|.|||:|.:.:||||:|||.:|
Worm     1 MGNSNSSILSDAEMREIMDETQFNKHQILRLYTRFASLDKNGQGYLSRDDFLNVPELAVNPLGDR 65

  Fly    66 IVHSFF------AESNDDRVNFRQFMNVLAHFRPLRDNKQSKLNSREEKLKFAFKMYDLDDDGVI 124
            |:.:||      .:|...::.||||:.:||||:|:...|.:.||||::||:||||||||:.:..|
Worm    66 IIDAFFTLGDSDGDSKSGQLTFRQFVRILAHFQPISKVKDNALNSRKDKLRFAFKMYDLNKNNYI 130

  Fly   125 SRDELLSILHMMVGANISQDQLVSIAERTILEADLCCQGKISFEDFCKALDRTDVDQKMSIRFLN 189
            :|:|...||:.||||||:.|||..||::|:.|||....|||||||||:|:::||:::|||:||||
Worm   131 TREEFKVILNSMVGANITSDQLDKIADKTLEEADQDRDGKISFEDFCRAMEKTDIEEKMSMRFLN 195

Fly 190 189
Worm 196 195

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
elm	NP_001262295.1	FRQ1	23..173	CDD:227455	82/155 (53%)
chpf-2	NP_503830.2	FRQ1	15..182	CDD:227455	86/166 (52%)
		EFh	35..95	CDD:298682	26/59 (44%)
		EFh	114..180	CDD:238008	39/65 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166873
Domainoid	1	1.000	118	1.000	Domainoid score	I3645
eggNOG	1	0.900	-	-		E2759_KOG0034
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5235
Inparanoid	1	1.050	217	1.000	Inparanoid score	I2313
Isobase	1	0.950	-	0	Normalized mean entropy	S676
OMA	1	1.010	-	-		QHG53747
OrthoDB	1	1.010	-	-		D1271942at2759
OrthoFinder	1	1.000	-	-		FOG0000640
OrthoInspector	1	1.000	-	-		otm14478
orthoMCL	1	0.900	-	-		OOG6_105864
Panther	1	1.100	-	-	O	PTHR46002
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2469
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	17	16.720