Protein Alignment elm and CHP1

DIOPT Version :10

• Sequence 1: NP_649568.1
• Gene: elm / 40695
• FlyBaseID: FBgn0037358
• Length: 189
• Species: Drosophila melanogaster
• Sequence 2: NP_009167.1
• Gene: CHP1 / 11261
• HGNCID: 17433
• Length: 195
• Species: Homo sapiens
• Alignment Length: 196
• Identity: 119/196 - (60%)
• Similarity: 150/196 - (76%)
• Gaps: 8/196 - (4%)

  Fly     1 MGNKSSLFLRNEEIAQIQEETGFTPNQIERLYSRFTSLDRNDCGTLSREDLMRIPELAINPLCER 65
            ||:::|..||:||:.:|::||||:.:||.||||||||||:.:.|||||||..||||||||||.:|
Human     1 MGSRASTLLRDEELEEIKKETGFSHSQITRLYSRFTSLDKGENGTLSREDFQRIPELAINPLGDR 65

  Fly    66 IVHSFFAESNDDRVNFRQFMNVLAHFRPLRDNKQSK-------LNSREEKLKFAFKMYDLDDDGV 123
            |:::||.| .:|:||||.||..||||||:.||::||       ||||..||.|||::||||.|..
Human    66 IINAFFPE-GEDQVNFRGFMRTLAHFRPIEDNEKSKDVNGPEPLNSRSNKLHFAFRLYDLDKDEK 129

  Fly   124 ISRDELLSILHMMVGANISQDQLVSIAERTILEADLCCQGKISFEDFCKALDRTDVDQKMSIRFL 188
            |||||||.:|.||||.|||.:||.|||:|||.|||......|||.:|.|.|::.||:||||||||
Human   130 ISRDELLQVLRMMVGVNISDEQLGSIADRTIQEADQDGDSAISFTEFVKVLEKVDVEQKMSIRFL 194

  Fly   189 N 189
            :
Human   195 H 195

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
elm	NP_649568.1	FRQ1	27..174	CDD:444056	96/153 (63%)
CHP1	NP_009167.1	Necessary for association with microtubule and interaction with GAPDH. /evidence=ECO:0000250	2..6		1/3 (33%)
		FRQ1	27..182	CDD:444056	97/155 (63%)
		Nuclear export signal 1. /evidence=ECO:0000250	138..147		5/8 (63%)
		Necessary for nuclear export signal	143..185		22/41 (54%)
		Nuclear export signal 2. /evidence=ECO:0000250	176..185		3/8 (38%)