DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment elm and CIB1

DIOPT Version :9

Sequence 1:	NP_001262295.1	Gene:	elm / 40695	FlyBaseID:	FBgn0037358	Length:	189	Species:	Drosophila melanogaster
Sequence 2:	XP_006720438.1	Gene:	CIB1 / 10519	HGNCID:	16920	Length:	264	Species:	Homo sapiens

Alignment Length:	189	Identity:	49/189 - (25%)
Similarity:	91/189 - (48%)	Gaps:	21/189 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGNKSSLFLRNEEIAQIQEETGFTPNQIERLYSRFTSL----DRNDCGTLSR----EDLMRIPEL 57
            ||...|. |..|.:|:.|:.|..|..:|...:.||..|    .|:...:|..    |.::.:|||
Human     1 MGGSGSR-LSKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPEL 64

  Fly    58 AINPLCERIVHSFFAESNDDRVNFRQFMNVLAHFRPLRDNKQSKLNSREEKLKFAFKMYDLDDDG 122
            ..||..|||...|......|.::|..|:::|:.|        |...:.:.|..:||:::|.||||
Human    65 KANPFKERICRVFSTSPAKDSLSFEDFLDLLSVF--------SDTATPDIKSHYAFRIFDFDDDG 121

  Fly   123 VISRDELLSILHMMVG----ANISQDQLVSIAERTILEADLCCQGKISFEDFCKALDRT 177
            .::|::|..:::.:.|    ..:|..::..:.:..:.|:|:...|.|:..:|...:.|:
Human   122 TLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRS 180

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
elm	NP_001262295.1	FRQ1	23..173	CDD:227455	40/161 (25%)
CIB1	XP_006720438.1	EF-hand_8	82..132	CDD:290545	16/57 (28%)
		EF-hand_7	109..177	CDD:290234	16/67 (24%)
		EFh	111..178	CDD:238008	16/66 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165156554
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0034
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1271942at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.750