DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Sec23 and AT4G01810

DIOPT Version :9

Sequence 1:	NP_001246932.1	Gene:	Sec23 / 40694	FlyBaseID:	FBgn0262125	Length:	781	Species:	Drosophila melanogaster
Sequence 2:	NP_001329285.1	Gene:	AT4G01810 / 828105	AraportID:	AT4G01810	Length:	880	Species:	Arabidopsis thaliana

Alignment Length:	781	Identity:	178/781 - (22%)
Similarity:	300/781 - (38%)	Gaps:	160/781 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 IQYEPVLCTRSNCRAILNPLCQVDYRAKLWVCNFCFQRNPFPPQYAAISEQH------------- 105
            ||.:|..|.  ||.|..||...:...:..|.|..|...|....:|.|.|:..
plant   197 IQRDPHRCL--NCGAYSNPYSSILIGSGQWQCVICENMNGSKGEYVASSKNELQNFPELSLPLVD 259

  Fly   106 --QPAELIPGFSTIEYTITRAPTMPPVFIFLVDTCMDEEELDALKDSLQMSLSLLPTNALVGLIT 168
              |.....|||.....:.|.||.     :.::|.|:||..|..|:.||...:..||....:|:|.
plant   260 YVQTGNKRPGFVPASDSRTSAPV-----VLVIDECLDEPHLQHLQSSLHAFVDSLPQTTRLGIIL 319

  Fly   169 FGKMIQVHELGAEGCSKSYVFRGTKDLTAKQVQDMLGIGRGAAPGPQQQQHLPGQPAGAAAPVPP 233
            :|:.:.:::...:..:.:.|..|.|..:|:.::.:: .|.|....|..            |.:..
plant   320 YGRTVSIYDFSEDSVASADVISGAKSPSAESMKALI-YGTGVYLSPMH------------ASLKV 371

  Fly   234 AHRFLQPIGQCDAALGDLLSELQRDPWPVPQGKRYLRSTGAALSIAVGLLE--------CTYPNT 290
            ||              ::.|.|:.....||:..|. |..|.|:..|:.:::        ......
plant   372 AH--------------EIFSSLRPYTLNVPEASRD-RCLGTAVEAALAIIQGPSAEMSRGVVRRA 421

  Fly   291 GG--RIMTFVGGPCSQGPGQVVDDELKHPIRSHHDIHKDNVRFMKK-AIKHYDALALRAATNGHS 352
            ||  ||:...|||.:.|||. |...:.||          |..:|:| |||..:.|...|..:...
plant   422 GGNSRIIVCAGGPITYGPGS-VPHSMSHP----------NYPYMEKTAIKWMENLGREAHRHNTV 475

  Fly   353 VDIYSCALDQTGLLEMKQLCNSTGGHMVMGDSFNSSLFKQTFQRVFARDGRNDLKMAFNATLEVK 417
            |||.........:..::.|..::||.:|:.|.|..: |....||...|...:      :..|||:
plant   476 VDILCAGTCPLRVPILQPLAKASGGVLVLHDDFGEA-FGVDLQRAATRAAGS------HGLLEVR 533

  Fly   418 CSRELKISGGIG--------------SCVSLNVKSPSVSDVEIGMGNTVQWKLCTLNPSSTVAYF 468
            ||.::.|:..||              |..:|:::..||.:       |..:.|...|..
plant   534 CSDDILITQVIGPGEEAHSETHETFKSDAALSIQMLSVEE-------TQSFSLSMENKR------ 585

  Fly   469 FEVVNQHAAPIPQGGRGCIQFITQYQHPSGQRRIRVTTLARNWADATSNVHHISA---GFDQEAA 530
             ::.:.|.         ..||...|.........||.|......|:      |||   ..:.||:
plant   586 -DIKSDHV---------FFQFAFHYSDVYQADVSRVITFKLPTVDS------ISAYLQSVEDEAS 634

  Fly   531 AVLMARMVVYRAETD-EGPDILRWVDRQLIRLCQKFGEYSKDDPNS--FRLSQNFSLFPQFMYHL 592
            |||:::..:..|:.. :..|:...||.::..:..|||   ...|.|  :...:..|..|:.::||
plant   635 AVLISKRTLLLAKNQKDAVDMRATVDERIKDIALKFG---SQVPKSKLYSFPKELSSLPELLFHL 696

  Fly   593 RRSQFLQVFNNSPDETTFYRHMLMREDLTQSLIMIQPILYSYSFNGPPEPVLLDTASIQADRILL 657
            ||...|.......||.:..|::.:......||.|:.|....:...|..|.:.....|:|:|:.::
plant   697 RRGPLLGNIIGHEDERSVLRNLFLNASFDLSLRMVAPRCLMHQEGGTFEELPAYDLSMQSDKAVI 761

  Fly   658 MDTFFQILIYHGETIAQWRALKYQDMPEYENFKQLLQAPVDDAQEILQTRFPMPRYIDTEHGGSQ 722
            :|        ||..:..|  |..:...:......:|.|....|:|:.:.|||.||.:..:.|.||
plant   762 LD--------HGTDVFIW--LGAELSADEVKSAAVLAACRTLAEELTEFRFPAPRILAFKEGSSQ 816

  Fly   723 ARFLLSKVNPSQTHNNMYAYGQAPIGQVTVDGGAPVLTDDVSLQL-----------FMEHLKKLA 776
            ||:.:.::.|:  |.:.....:|...|:.      .||.:..::|           |.|.::.|.
plant   817 ARYFVCRLIPA--HKDPPYEQEARFPQIR------TLTTEQRMKLKSSFIEFDEASFCEWMRSLK 873

  Fly   777 V 777
            |
plant   874 V 874

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sec23	NP_001246932.1	PLN00162	12..779	CDD:215083	178/781 (23%)
		zf-Sec23_Sec24	58..97	CDD:282641	11/38 (29%)
		Sec23-like	126..396	CDD:238755	63/280 (23%)
		Sec23_BS	409..512	CDD:285301	22/116 (19%)
		Sec23_helical	530..623	CDD:282646	22/95 (23%)
		Sec23_C	618..738	CDD:200443	30/119 (25%)
AT4G01810	NP_001329285.1	PHA03247	<17..128	CDD:223021
		SEC23	196..826	CDD:227380	167/723 (23%)
		trunk_domain	275..518	CDD:238745	66/287 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5047
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11141
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910