Protein Alignment Sec23 and sec-23

DIOPT Version :10

• Sequence 1: NP_001246932.1
• Gene: Sec23 / 40694
• FlyBaseID: FBgn0262125
• Length: 781
• Species: Drosophila melanogaster
• Sequence 2: NP_507877.1
• Gene: sec-23 / 180317
• WormBaseID: WBGene00004754
• Length: 821
• Species: Caenorhabditis elegans
• Alignment Length: 835
• Identity: 486/835 - (58%)
• Similarity: 611/835 - (73%)
• Gaps: 68/835 - (8%)

  Fly     1 MTTYEEFIQQNEDRDGVRLTWNVWPSSRIEASRLVVPLACLYQPLKERPDL----PPIQYEPVLC 61
            |.|:||::...:..|||:.|||:||.||:::.:|||||.|.:.||||||..    ||::|:||||
 Worm     1 MATWEEYLGAQQANDGVQFTWNMWPHSRVDSQKLVVPLTCFFTPLKERPSTEVAQPPLEYDPVLC 65

  Fly    62 TRSNCRAILNPLCQVDYRAKLWVCNFCFQRNPFPPQYAAISEQHQPAELIPGFSTIEYTITRAPT 126
            .:::|:|||||||.||||||:|:|.||..|||||..||||:|.::|.||.|.|:|||||:.:|.|
 Worm    66 QKASCKAILNPLCAVDYRAKIWMCPFCNNRNPFPAHYAAIAEDNRPPELYPQFTTIEYTLRKATT 130

  Fly   127 MPPVFIFLVDTCMDEEELDALKDSLQMSLSLLPTNALVGLITFGKMIQVHELGAEGCSKSYVFRG 191
            |||:|:|:|||||..|||.:||:.||.:|||||.:|||||||:|:|:|:|||..:|.|:||||:|
 Worm   131 MPPIFVFVVDTCMTAEELKSLKECLQTALSLLPADALVGLITYGRMVQLHELNTQGISRSYVFKG 195

  Fly   192 TKDLTAKQVQDM-------------------------LGIGRGAAP-----------------GP 214
            ||::||||::|:                         :.:|.||||                 ||
 Worm   196 TKEVTAKQIKDVMAGGGLSQRPAAGAPGAPAGAPGAPMAMGSGAAPLGQLPGSGLPGGLPRGGGP 260

  Fly   215 QQQQHLPGQ-----PAGAAAPVP--PAHRFLQPIGQCDAALGDLLSELQRDPWPVPQGKRYLRST 272
            .    |||.     ..|..||||  ||::|||||.:||.::.||:.::..|.||||||.|.||:|
 Worm   261 P----LPGAAQGIVAPGGGAPVPHAPANKFLQPISECDESINDLIDQISIDRWPVPQGHRPLRAT 321

  Fly   273 GAALSIAVGLLECTYPNTGGRIMTFVGGPCSQGPGQVVDDELKHPIRSHHDIHKDNVRFMKKAIK 337
            ||||::||.|||..:|:||.|||:|:||.|:.|||.||.:|||:||||.:.|.:|...:||||||
 Worm   322 GAALAVAVTLLESCFPSTGARIMSFIGGACTHGPGAVVGEELKNPIRSWNSIKEDAAPYMKKAIK 386

  Fly   338 HYDALALRAATNGHSVDIYSCALDQTGLLEMKQLCNSTGGHMVMGDSFNSSLFKQTFQRVFARDG 402
            .||.||.|...|||:||:||||||||||||||.:.||:|||:||||||||||||||:||.|.:|.
 Worm   387 FYDGLAARIVKNGHAVDVYSCALDQTGLLEMKNMFNSSGGHVVMGDSFNSSLFKQTYQRSFDKDS 451

  Fly   403 RNDLKMAFNATLEVKCSRELKISGGIGSCVSLNVKSPSVSDVEIGMGNTVQWKLCTLNPSSTVAY 467
            ..:|||.||||:|||....|||.|.:|.|.|.||::.:|||.|:|:|.|.|||...::|.:|:..
 Worm   452 AGNLKMGFNATMEVKVGAGLKIEGVLGCCASGNVRNANVSDQEMGIGGTCQWKFGAISPRTTIGV 516

  Fly   468 FFEVVNQHAAPIPQGGRGCIQFITQYQHPSGQRRIRVTTLARNWADATSNVHHISAGFDQEAAAV 532
            .||:..||.:.|||||||.:||:|||||..|::||||||..|.|||..:...:|:.|||||||||
 Worm   517 VFEIAAQHGSAIPQGGRGMVQFVTQYQHADGRKRIRVTTTCRTWADMATQQPNIAYGFDQEAAAV 581

  Fly   533 LMARMVVYRAETD-EGPDILRWVDRQLIRLCQKFGEYSKDDPNSFRLSQNFSLFPQFMYHLRRSQ 596
            .:||:..:||..: :.|:.|||:||.||||||||||||||||||||||..||||||||:||||||
 Worm   582 AIARLASFRASNENDTPEALRWLDRSLIRLCQKFGEYSKDDPNSFRLSDKFSLFPQFMFHLRRSQ 646

  Fly   597 FLQVFNNSPDETTFYRHMLMREDLTQSLIMIQPILYSYSFNGPPEPVLLDTASIQADRILLMDTF 661
            ||||||||||||.:|||:|..|::.:|..||||:|:|||||||||||||||:||.||||||||.:
 Worm   647 FLQVFNNSPDETAYYRHILFSENVLESTTMIQPVLFSYSFNGPPEPVLLDTSSILADRILLMDDY 711

  Fly   662 FQILIYHGETIAQWRALKYQDMPEYENFKQLLQAPVDDAQEILQTRFPMPRYIDTEHGGSQARFL 726
            |.:|||||:||||||...:.:.|:|..|||||:|||.||..|||.||||||||.|||.|||||||
 Worm   712 FHVLIYHGQTIAQWRKQNFHENPQYATFKQLLEAPVADATSILQERFPMPRYIVTEHEGSQARFL 776

  Fly   727 LSKVNPSQTHNNMYAYGQAPIGQVTVDGGAPVLTDDVSLQLFMEHLKKLAVSTTT 781
            |||||||.||||.||.          :.|:.|.|||||||:||||||||:.|::|
 Worm   777 LSKVNPSLTHNNPYAN----------EAGSAVFTDDVSLQVFMEHLKKLSSSSST 821

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sec23	NP_001246932.1	PLN00162	12..779	CDD:215083	480/820 (59%)
sec-23	NP_507877.1	PLN00162	12..811	CDD:215083	474/812 (58%)