DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment MTA1-like and mta1

DIOPT Version :9

Sequence 1:	NP_001262293.1	Gene:	MTA1-like / 40693	FlyBaseID:	FBgn0027951	Length:	922	Species:	Drosophila melanogaster
Sequence 2:	XP_031746259.1	Gene:	mta1 / 496581	XenbaseID:	XB-GENE-1007626	Length:	704	Species:	Xenopus tropicalis

Alignment Length:	915	Identity:	373/915 - (40%)
Similarity:	491/915 - (53%)	Gaps:	247/915 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MATNMYRVGDYVYVETTPNSPYLIRRIEELNKNQTGNVEAKVMCFYRRRDLPNPLVQLADKHQLA 65
            ||.||||||||||.|.:.::||||||||||||...|||||||:|||||||:.:.|:.|||||
Frog     1 MAANMYRVGDYVYFENSSSNPYLIRRIEELNKTANGNVEAKVVCFYRRRDISSTLISLADKH--- 62

  Fly    66 TAEDSPLATKLKKTWLRTPVSEEQAAQAVLDPSIAALDEERTSPTQTSGGGGSATGNSGSNSSGT 130
                                             ...::||..:|....
Frog    63 ---------------------------------AREMEEEMENPEMVD----------------- 77

  Fly   131 SNNNSSSTAIGGGAGGSGGAGGDAEKGEALTSKQRYQIKHRELFLSRQVESIPATQIRGKCSVTL 195
                                         |..|.::|::|||||||||:||:|||.|||||||||
Frog    78 -----------------------------LPEKLKHQLRHRELFLSRQLESLPATHIRGKCSVTL 113

  Fly   196 LNETESLQSYLNKDDTFFYCLVFDPNQKTLLADKGEIRVGSRYQCDIPAKLKDTATDDRKLEELE 260
            |||||||:|||.::|.|||.||:||.||||||||||||||:|||.||...|::.|.|.|....||
Frog   114 LNETESLKSYLEREDFFFYSLVYDPQQKTLLADKGEIRVGNRYQADITDLLEEGAEDGRDQANLE 178

  Fly   261 SLVWTPEHSLTDRKIDQFLVVSRSIGTFARALDCSSSVKQPSLHMSAAAASRDITLFHAMNILHK 325
            :.||...:.|||::|||||||:||:|||||||||||||:|||||||||||||||||||||:.|||
Frog   179 TKVWEASNPLTDKQIDQFLVVARSVGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLHK 243

  Fly   326 HEYSIEESMSSLVPSTGPVLCRDEIEDWSASEANLFEEALEKYGKDFNDIRQDFLPWKTLKQIIE 390
            :.|.|.:::|:|||..||||||||:|:||||||||||||||||||||.||:|||||||:|..|||
Frog   244 NTYDISKAISALVPQGGPVLCRDEMEEWSASEANLFEEALEKYGKDFTDIQQDFLPWKSLTSIIE 308

  Fly   391 YYYMWKTTDRYVQQKRVKAVEAELKLKQVYIPQYN--NNGKGNGTSTKAGGGIYNGTTNGSTDLS 453
            ||||||||||||||||:||.|||.||||||||.||  |..:.|..:.|.  .:.|||.....:::
Frog   309 YYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPNYNKPNPNQINVNNVKP--AVVNGTAVQGQNVA 371

  Fly   454 ---SNGKPCESCGTTKSSQWNSVSSGHSTSRLCLSCWEYWRRYGSMKSATKGDAGEGDAKKKSSS 515
               :..:.||||.||:|.||.|....:...|||.|||.||::||.:|..|:.| ||.....:::.
Frog   372 VGRACERACESCYTTQSYQWYSWGPPNMQCRLCASCWAYWKKYGGLKMPTRLD-GERPGPNRNNM 435

  Fly   516 AASTPTATLAGLATTPTAVVDLNDDEKISDLTNRQLHRCSIVNCGKEFKLKTHLARHYAQAHGIA 580
            :                                                           .||:.
Frog   436 S-----------------------------------------------------------PHGLP 441

  Fly   581 I-SSGSPRPIMKTRTAFYLHTNPMTRVARAICRSIVKPKKAARQSAYAINAMLVKQEFTNRISGK 644
            : :||||:..||||.||||||..:|::||.:||.|.:|:.|||.....||:..:|.|.|.|:...
Frog   442 MRNSGSPKFAMKTRQAFYLHTTKLTKIARRLCRDIFRPRYAARHPYMPINSAAIKAECTTRLPEA 506

  Fly   645 SQAEIKKLLLLKPKDRGSVTKIANRLGAPGSGPHEWLVLTPKDKMPLPAVVSF----PKPPKAPD 705
            |:..                                |:|....:.||..|:.:    |.|||
Frog   507 SKTP--------------------------------LILKQVVRKPLEEVMRYIEAHPCPPK--- 536

  Fly   706 GSLVYDRVPNKSPDVVAVPADKELTIIPTQATSTIR--------KRAHEDQQLNGTEVTIVPSGP 762
                .|.:.|.|..:     :..||  ||:::..|.        ||::|  |.||.:      |.
Frog   537 ----QDLIKNISTSI-----NNSLT--PTKSSPVINNGSPTILGKRSYE--QHNGMD------GN 582

  Fly   763 PAKR---PNKDP---MPSHCPSPEQFAAMMAASGQ-----PLSRHHLNGKQKIA--QMARGG--- 811
            ..||   |::..   :|:|              ||     |.....||||...|  ::.|||
Frog   583 VKKRLLMPSRGTYFGIPNH--------------GQTRQMGPNRNLLLNGKSYPAKVRLIRGGCMP 633

  Fly   812 NGRKQVISWMDAPDDVYFRANDTHKKTRKILSAVDLRRAARKPWRTLPIKPA-APEPSSRPIESQ 875
            ..:::.::|:||||||::.|.:..:|.||:||:.:.:||||:|:|.:.|:.| ..:...:|:..:
Frog   634 PVKRRRMNWIDAPDDVFYMATEETRKVRKLLSSSETKRAARRPYRHIVIRQAQVGQLMRQPVNDE 698

  Fly   876 IVILD 880
            .::::
Frog   699 PIVIE 703

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MTA1-like	NP_001262293.1	BAH_MTA	3..253	CDD:240060	111/249 (45%)
		ELM2	232..284	CDD:279754	27/51 (53%)
		SANT_MTA3_like	352..397	CDD:212559	38/44 (86%)
		SANT	353..398	CDD:197842	39/44 (89%)
		ZnF_GATA	458..508	CDD:238123	25/49 (51%)
mta1	XP_031746259.1	BAH_MTA	3..171	CDD:240060	111/249 (45%)
		ELM2	150..202	CDD:396160	27/51 (53%)
		SANT_MTA3_like	270..315	CDD:212559	38/44 (86%)
		ZnF_GATA	377..428	CDD:214648	25/51 (49%)
		MTA_R1	451..527	CDD:407344	32/107 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	111	1.000	Domainoid score	I6201
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3442
Inparanoid	1	1.050	602	1.000	Inparanoid score	I934
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D347549at33208
OrthoFinder	1	1.000	-	-		FOG0002092
OrthoInspector	1	1.000	-	-		otm48262
Panther	1	1.100	-	-	LDO	PTHR10865
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1382
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	11.070