Protein Alignment MTA1-like and Mta3

DIOPT Version :10

• Sequence 1: NP_001262293.1
• Gene: MTA1-like / 40693
• FlyBaseID: FBgn0027951
• Length: 922
• Species: Drosophila melanogaster
• Sequence 2: XP_006523574.1
• Gene: Mta3 / 116871
• MGIID: 2151172
• Length: 637
• Species: Mus musculus
• Alignment Length: 768
• Identity: 331/768 - (43%)
• Similarity: 429/768 - (55%)
• Gaps: 182/768 - (23%)

  Fly     1 MATNMYRVGDYVYVETTPNSPYLIRRIEELNKNQTGNVEAKVMCFYRRRDLPNPLVQLADKHQLA 65
            ||.||||||||||.|.:.::||||||||||||..:|||||||:|||||||:.|.|:.|||||...
Mouse     1 MAANMYRVGDYVYFENSSSNPYLIRRIEELNKTASGNVEAKVVCFYRRRDISNTLIMLADKHAKE 65

  Fly    66 TAEDSPLATKLKKTWLRTPVSEEQAAQAVLDPSIAALDEERTSPTQTSGGGGSATGNSGSNSSGT 130
            |.|:|           .|||..:
Mouse    66 TEEES-----------ETPVEAD------------------------------------------ 77

  Fly   131 SNNNSSSTAIGGGAGGSGGAGGDAEKGEALTSKQRYQIKHRELFLSRQVESIPATQIRGKCSVTL 195
                                         ||.||::|:||||||||||.||:|||.|||||||.|
Mouse    78 -----------------------------LTEKQKHQLKHRELFLSRQYESLPATHIRGKCSVAL 113

  Fly   196 LNETESLQSYLNKDDTFFYCLVFDPNQKTLLADKGEIRVGSRYQCDIPAKLKDTATDDRKLEELE 260
            ||||||:.|||:|:|||||.||:||:.|||||||||||||.:||.|||..|.:..:|:|:..:||
Mouse   114 LNETESVLSYLDKEDTFFYSLVYDPSVKTLLADKGEIRVGPKYQADIPDMLPEGDSDEREQSKLE 178

  Fly   261 SLVWTPEHSLTDRKIDQFLVVSRSIGTFARALDCSSSVKQPSLHMSAAAASRDITLFHAMNILHK 325
            ..||.|...||||:|||||||:|::|||||||||||||:|||||||||||||||||||||:.|::
Mouse   179 VKVWDPNSPLTDRQIDQFLVVARAVGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLYR 243

  Fly   326 HEYSIEESMSSLVPSTGPVLCRDEIEDWSASEANLFEEALEKYGKDFNDIRQDFLPWKTLKQIIE 390
            |.|.:..::|.|||..||||||||:|:||||||.||||||||||||||||||||||||:|..|||
Mouse   244 HGYDLSSAISVLVPLGGPVLCRDEMEEWSASEACLFEEALEKYGKDFNDIRQDFLPWKSLTSIIE 308

  Fly   391 YYYMWKTTDRYVQQKRVKAVEAELKLKQVYIPQYNNNGKGNGTSTKAGGGIYNGT--TNGSTDLS 453
            ||||||||||||||||:||.|||.||||||||.|:.......:|:....|..||.  |......:
Mouse   309 YYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPTYSKPNPNQISSSNGKAGTVNGAVGTQFQPQSA 373

  Fly   454 SNGKPCESCGTTKSSQWNSVSSGHSTSRLCLSCWEYWRRYGSMKSATKGDAGEGDAKKKSSSAAS 518
            ..|:.||||..|:|.||.|....:...|||.:||.||::||.:|..|     :.|.:|..|..|.
Mouse   374 LLGRACESCYATQSHQWYSWGPPNMQCRLCATCWLYWKKYGGLKMPT-----QSDEEKSPSPTAE 433

  Fly   519 TPTATLAGLATTPTAVVDLNDDEKISDLTNRQLHRCSIVNCGKEFKLKTHLARHYAQAHGIAI-S 582
            .|.|                                           ::|::|...|  |:.: :
Mouse   434 DPRA-------------------------------------------RSHMSRQALQ--GMPVRN 453

  Fly   583 SGSPRPIMKTRTAFYLHTNPMTRVARAICRSIVKPKKAARQSAYAINAMLVKQEFTNRISGKSQA 647
            :|||:..:|||.||:|.|...|::||.:|:|.::.::|||:...|||...::.|:.:|     .|
Mouse   454 TGSPKSAVKTRQAFFLRTTYFTKIARQVCKSTLRLRQAARRPFVAINYAAIRAEYADR-----HA 513

  Fly   648 EIKKLLLLKPKDRGSVTKIANRLGAPGSGPHEWLVLTPKDKMPLPAVVSFPK--PPKAPDGSLVY 710
            |:.                    |:|        :.:...:.||..::.:.:  |.|.|:
Mouse   514 ELS--------------------GSP--------LKSRSTRKPLSCIIGYLEIHPAKKPN----- 545

  Fly   711 DRVPNKSPDVVAVPADKELTIIPTQATSTI---RKRAHEDQQLNGTEVTIVPS 760
               ..:||..:..||.|.:...|...:.:|   |..:|.: .|:.:::.:|.|
Mouse   546 ---VIRSPPSLQTPATKRMLAAPNHTSLSILGKRNYSHHN-GLDASKIRMVNS 594

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MTA1-like	NP_001262293.1	BAH_MTA	3..253	CDD:240060	116/249 (47%)
		ELM2	232..284	CDD:460214	28/51 (55%)
		SANT_MTA3_like	352..397	CDD:212559	39/44 (89%)
		ZnF_GATA	458..508	CDD:238123	20/49 (41%)
		MTA_R1	589..670	CDD:465388	22/80 (28%)
Mta3	XP_006523574.1	BAH_MTA	3..170	CDD:240060	116/248 (47%)
		ELM2	150..201	CDD:460214	28/50 (56%)
		SANT_MTA3_like	270..315	CDD:212559	39/44 (89%)
		ZnF_GATA	376..427	CDD:214648	22/55 (40%)
		MTA_R1	460..536	CDD:465388	26/108 (24%)