DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12170 and KASI

DIOPT Version :9

Sequence 1:	NP_649565.1	Gene:	CG12170 / 40692	FlyBaseID:	FBgn0037356	Length:	438	Species:	Drosophila melanogaster
Sequence 2:	NP_001190479.1	Gene:	KASI / 834671	AraportID:	AT5G46290	Length:	489	Species:	Arabidopsis thaliana

Alignment Length:	458	Identity:	175/458 - (38%)
Similarity:	269/458 - (58%)	Gaps:	35/458 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LVRQTRSLSTPSG------------RRRVVVTGSGAVTPLGNNGPDSWRRILAGESAISRLSA-E 61
            |.||.||..:.|.            ::|||:||.|.|:..||:....:.::|:|||.||.:.. :
plant    35 LRRQQRSFISASASTVSAPKRETDPKKRVVITGMGLVSVFGNDVDAYYEKLLSGESGISLIDRFD 99

  Fly    62 FKGLPCQVAAQIPRENLQLDQHLTKSDIKLMSPATQLAVLAAEEALSTGKLCPKQLSEEELERFG 126
            ....|.:...||  .....:.::...:.:.:....:..::|.::||.:..|...:|:..:..:.|
plant   100 ASKFPTRFGGQI--RGFSSEGYIDGKNERRLDDCLKYCIVAGKKALESANLGGDKLNTIDKRKAG 162

  Fly   127 VCVGMGMFDLAEVY--GAWNQLQRGYNRVSPFFVPRLLPSMACGHISMRHGLRGPNHSVSTACAT 189
            |.||.||..|. |:  |..|.:::|:.|:||||:|..:.:|....:::..||.|||:|:||||||
plant   163 VLVGTGMGGLT-VFSEGVQNLIEKGHRRISPFFIPYAITNMGSALLAIDLGLMGPNYSISTACAT 226

  Fly   190 GAHALGDAMRFIRSGDADLMLAGSGEACIDPLSIAGFCRLRALSTAFNDNPAVASRPFDKSRDGF 254
            ..:....|...||.|:||:|:||..||.|.|:.:.||...||||.. ||:|..||||:||:||||
plant   227 SNYCFYAAANHIRRGEADMMIAGGTEAAIIPIGLGGFVACRALSQR-NDDPQTASRPWDKARDGF 290

  Fly   255 VMGEGAAVLLLEELEHARARGAPILAEILGYGLSGDAYHITSPSDDGAGATLAMKRAIQDAGIAP 319
            ||||||.||::|.||||..|||||:||.||..::.||:|:|.|..||.|.:..::|.::|||::|
plant   291 VMGEGAGVLVMESLEHAMKRGAPIVAEYLGGAVNCDAHHMTDPRADGLGVSSCIERCLEDAGVSP 355

  Fly   320 EDVTYVNAHATSTPTGDRIESHAIGRVFGAHTPQVRVSSTKGAHGHLLGSSGNLEALFVVLACAN 384
            |:|.|:|||||||..||..|.:||.:||.: |..:::::||...||.||::|.|||:..|.|...
plant   356 EEVNYINAHATSTLAGDLAEINAIKKVFKS-TSGIKINATKSMIGHCLGAAGGLEAIATVKAINT 419

  Fly   385 NKLPPSIN----IEHLDVDVNVV-----TKATDWSA--DQKRR----VALKNSFGFGGTNASLCI 434
            ..|.||||    |.......:::     .:|.|:..  ::|::    ||:.|||||||.|:.:..
plant   420 GWLHPSINQFVRITGSQEKASLIPLSNPEQAVDFDTVPNEKKQHEVDVAISNSFGFGGHNSVVAF 484

  Fly   435 ASY 437
            :::
plant   485 SAF 487

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12170	NP_649565.1	PRK07314	23..437	CDD:235987	169/431 (39%)
CG12170	NP_649565.1	KAS_I_II	24..434	CDD:238430	169/427 (40%)
KASI	NP_001190479.1	PRK06333	59..489	CDD:235781	169/434 (39%)
KASI	NP_001190479.1	KAS_I_II	61..484	CDD:238430	169/427 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0304
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53767
OrthoDB	1	1.010	-	-		D1014523at2759
OrthoFinder	1	1.000	-	-		FOG0002908
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100752
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.730