DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12170 and AT2G04540

DIOPT Version :9

Sequence 1:	NP_649565.1	Gene:	CG12170 / 40692	FlyBaseID:	FBgn0037356	Length:	438	Species:	Drosophila melanogaster
Sequence 2:	NP_178533.2	Gene:	AT2G04540 / 814996	AraportID:	AT2G04540	Length:	461	Species:	Arabidopsis thaliana

Alignment Length:	451	Identity:	213/451 - (47%)
Similarity:	287/451 - (63%)	Gaps:	30/451 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 VRQTRSLSTPS---GRRRVVVTGSGAVTPLGNNGPDSWRRILAGESAISRLSAE----------- 61
            :|..|.:||.|   ..|||||||.|.|||||.....:|||::.||..|..|:.:
plant    15 LRLNRFISTSSSYHSHRRVVVTGLGMVTPLGRGVETTWRRLIDGECGIRGLTLDDLKMKSFDEET 79

  Fly    62 ----FKGLPCQVAAQIPRENL--QLDQHLTKSDIKLMSPATQLAVLAAEEALSTGKLCPKQLSEE 120
                |..|..:|||.:|..:.  :.|:.|..:. |.::.....||.||:|||...:..|.:  ||
plant    80 KLYTFDQLSSKVAAFVPYGSNPGEFDEALWLNS-KAVANFIGYAVCAADEALRDAEWLPTE--EE 141

  Fly   121 ELERFGVCVGMGMFDLAEVYGAWNQL-QRGYNRVSPFFVPRLLPSMACGHISMRHGLRGPNHSVS 184
            |.||.||.:|.|:..:.::..|...: ::...|:||||:|::|.:||.||:||::|.:||||:..
plant   142 EKERTGVSIGGGIGSICDIVEAAQLICEKRLRRLSPFFIPKILVNMASGHVSMKYGFQGPNHAAV 206

  Fly   185 TACATGAHALGDAMRFIRSGDADLMLAGSGEACIDPLSIAGFCRLRALSTAFNDNPAVASRPFDK 249
            ||||||||::|||.|.|:.||||:|:||..|:.||.||:|||.|.|||||.||.:|..||||||.
plant   207 TACATGAHSIGDATRMIQFGDADVMVAGGTESSIDALSVAGFSRSRALSTKFNSSPQEASRPFDC 271

  Fly   250 SRDGFVMGEGAAVLLLEELEHARARGAPILAEILGYGLSGDAYHITSPSDDGAGATLAMKRAIQD 314
            .|||||:|||:.|::|||.|||:.|||.|.||:.|||:||||:|||.|.:||.||.|||.||::.
plant   272 DRDGFVIGEGSGVIVLEEYEHAKRRGAKIYAELCGYGMSGDAHHITQPPEDGKGAVLAMTRALRQ 336

  Fly   315 AGIAPEDVTYVNAHATSTPTGDRIESHAIGRVFGAHTPQ--VRVSSTKGAHGHLLGSSGNLEALF 377
            :|:.|..:.||||||||||.||.:|:.||..||..|...  :..||||||.|||||::|.:||:|
plant   337 SGLCPNQIDYVNAHATSTPIGDAVEARAIKTVFSEHATSGTLAFSSTKGATGHLLGAAGAVEAIF 401

  Fly   378 VVLACANNKLPPSINIEHLD--VDVNVVTKATDWSADQKRRVALKNSFGFGGTNASLCIAS 436
            .:||..:...|.::|:::.|  .|...:...|  |.....|.|:.||||||||||||..||
plant   402 SILAIHHGVAPMTLNVKNPDPIFDKRFMPLTT--SKKMLVRTAMSNSFGFGGTNASLLFAS 460

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12170	NP_649565.1	PRK07314	23..437	CDD:235987	208/436 (48%)
CG12170	NP_649565.1	KAS_I_II	24..434	CDD:238430	206/431 (48%)
AT2G04540	NP_178533.2	PLN02836	26..461	CDD:215449	208/440 (47%)
AT2G04540	NP_178533.2	KAS_I_II	31..458	CDD:238430	206/431 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	215	1.000	Domainoid score	I753
eggNOG	1	0.900	-	-		E1_COG0304
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5820
Inparanoid	1	1.050	373	1.000	Inparanoid score	I559
OMA	1	1.010	-	-		QHG53767
OrthoDB	1	1.010	-	-		D1014523at2759
OrthoFinder	1	1.000	-	-		FOG0002908
OrthoInspector	1	1.000	-	-		oto3587
orthoMCL	1	0.900	-	-		OOG6_100752
Panther	1	1.100	-	-	LDO	PTHR11712
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2728
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	13	12.880