Protein Alignment CG12170 and FASN1

DIOPT Version :9

• Sequence 1: NP_649565.1
• Gene: CG12170 / 40692
• FlyBaseID: FBgn0037356
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: NP_001137778.2
• Gene: FASN1 / 33524
• FlyBaseID: FBgn0283427
• Length: 2540
• Species: Drosophila melanogaster
• Alignment Length: 414
• Identity: 108/414 - (26%)
• Similarity: 173/414 - (41%)
• Gaps: 55/414 - (13%)

  Fly    39 NNGPDSWRRILAGESAISRLSAEFKGLPCQVAAQIPRENLQLDQH---LTKSDIKLMSPATQLAV 100
            |:.|..|.|.|             .|||.::......:....||.   :.:...:.|.|..::.:
  Fly   172 NDDPRRWERGL-------------YGLPDRIGKLKDSDLENFDQQFFGVHQKQAECMDPLLRMLL 223

  Fly   101 LAAEEALSTGKLCPKQLSEEELERFGVCVGMGMFDLAEVYGAWNQLQRGYNRVSPFFVPRLLPSM 165
            ....||:....|.|..|..   .|.||.:|:..   :|....|..   ..:||:.:.:.....:|
  Fly   224 ELTHEAIIDAGLNPSDLRG---SRTGVYIGVSN---SETEQHWCS---DADRVNGYGLTGCARAM 279

  Fly   166 ACGHISMRHGLRGPNHSVSTACATGAHALGDAMRFIRSGDAD-LMLAGSGEACIDPLSIAGFCRL 229
            ....||.....:||::|:.|||::..:||..|...:|.|..| .::||:| ..:.|.....|.||
  Fly   280 FANRISFTFDFKGPSYSIDTACSSSLYALEQAFSDMREGKVDNALVAGAG-LILKPTMSLQFKRL 343

  Fly   230 RALSTAFNDNPAVASRPFDKSRDGFVMGEGAAVLLLEELEHARARGAPILAEILGYGLSGDAYH- 293
            ..||      |..:.:.||:|.:|:|..:|..||||:....||.    :.|.||....:.|.:.
  Fly   344 NMLS------PDGSCKAFDESGNGYVRSDGCVVLLLQRTSAARR----VYASILNVRTNTDGFKE 398

  Fly   294 --ITSPSDDGAGATLAMKRAIQDAGIAPEDVTYVNAHATSTPTGDRIESHAIGRVF-GAHTPQVR 355
              ||.|.  |......::...::.|:.|.||.||.||.|.|..||..|.::|...| ...|..:.
  Fly   399 QGITYPI--GKMQNRLIRETYEEIGLNPADVVYVEAHGTGTKVGDPQEVNSITDFFCKDRTTPLL 461

  Fly   356 VSSTKGAHGHLLGSSGNLEALFVVLACANNKLPPSINIEH--------LDVDVNVVTKATDWSAD 412
            :.|.|...||...:||......:::|.....:|.:::...        :|..:.||.:...|:..
  Fly   462 IGSVKSNMGHSEPASGVCSVAKILIAMEEGVIPGNLHYNKPNPDLYGLVDGRLKVVDRNLPWNGG 526

  Fly   413 QKRRVALKNSFGFGGTNASLCIAS 436
                :...|||||||.||.:.:.|
  Fly   527 ----IIGLNSFGFGGANAHVILKS 546

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12170	NP_649565.1	PRK07314	23..437	CDD:235987	108/414 (26%)
		KAS_I_II	24..434	CDD:238430	107/410 (26%)
FASN1	NP_001137778.2	PksD	137..1142	CDD:225858	108/414 (26%)
		PKS	140..544	CDD:238429	107/410 (26%)
		KAsynt_C_assoc	502..612	CDD:292814	14/49 (29%)
		Acyl_transf_1	633..950	CDD:298668
		hot_dog	990..1234	CDD:294345
		NADB_Rossmann	1358..>1550	CDD:304358
		PKS_ER	1593..1883	CDD:214840
		enoyl_red	1595..1883	CDD:176179
		KR_1_FAS_SDR_x	<1901..2141	CDD:187657
		PKS_PP	2154..>2206	CDD:214834
		Abhydrolase	2286..2535	CDD:304388

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442236
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840