DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG12170 and SPBC887.13c

DIOPT Version :9

Sequence 1:	NP_649565.1	Gene:	CG12170 / 40692	FlyBaseID:	FBgn0037356	Length:	438	Species:	Drosophila melanogaster
Sequence 2:	NP_596487.1	Gene:	SPBC887.13c / 2541226	PomBaseID:	SPBC887.13c	Length:	426	Species:	Schizosaccharomyces pombe

Alignment Length:	426	Identity:	191/426 - (44%)
Similarity:	273/426 - (64%)	Gaps:	13/426 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 RRVVVTGSGAVTPLGNNGPDSWRRILAGESAISRLSA--EFKGLPCQVAAQIPR----ENLQLDQ 82
            :|||:||.||||||||....:||.::.|:|.|..|..  |::.:|.:||..|||    |...:..
pombe     2 KRVVITGLGAVTPLGNGVKTNWRNLIQGKSGIVSLKGFPEYEQIPSKVAGVIPRGKEKEEWNVLD 66

  Fly    83 HLTKSDIKLMSPATQLAVLAAEEALSTGKLCPKQLSEEELERFGVCVGMGMFDLAEVYGAWNQLQ 147
            ::.:..::.::..||||:.:|.|||...:..  .:.|:|....|||.|.|:.:|.:.......|.
pombe    67 YVDQGKLREVATFTQLALTSAAEALKDARWI--DIDEQEKLATGVCFGTGIGNLDDALNENGVLN 129

  Fly   148 R-GYNRVSPFFVPRLLPSMACGHISMRHGLRGPNHSVSTACATGAHALGDAMRFIRSGDADLMLA 211
            : |..:|||..:.::|.:|..|:||.|:|....||:.:||||.|.||:|||..||:.|.||:::|
pombe   130 KAGIRKVSPRVISKILINMPAGYISQRYGFTALNHTTTTACAAGCHAIGDAFNFIKLGHADVIIA 194

  Fly   212 GSGEACIDPLSIAGFCRLRALSTAFNDNPAVASRPFDKSRDGFVMGEGAAVLLLEELEHARARGA 276
            |..|:||:||::|||.:.|:|||.|||||..||||||.:|||||:|||:|.|:|||||||:.|.|
pombe   195 GGSESCINPLTVAGFSKARSLSTKFNDNPKAASRPFDANRDGFVIGEGSAALVLEELEHAKNRNA 259

  Fly   277 PILAEILGYGLSGDAYHITSPSDDGAGATLAMKRAIQDAGIAPEDVTYVNAHATSTPTGDRIESH 341
            .|.|||:||||:.|:||||:|:.:|..|..||||:::.||::...:.|:|||||||..||..||.
pombe   260 HIYAEIVGYGLASDSYHITAPNPNGDAAYYAMKRSLKQAGLSASQLDYINAHATSTKLGDVAESI 324

  Fly   342 AIGRVF---GAHTPQVRVSSTKGAHGHLLGSSGNLEALFVVLACANNKLPPSINIEHLDVDVNVV 403
            ||.|:.   ..:.....|||:||:.|||||::|.:|:::.||......|||::|.|:.|:.....
pombe   325 AITRLLCDVNRNPEAFPVSSSKGSIGHLLGAAGAIESVYTVLTVQKGVLPPTLNFEYSDIPQQFQ 389

  Fly   404 TKATDWSADQKR-RVALKNSFGFGGTNASLCIASYI 438
            .......|.:.| .|||.|||||||||||||...::
pombe   390 CDYVPNVAKESRINVALSNSFGFGGTNASLCFKKFL 425

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12170	NP_649565.1	PRK07314	23..437	CDD:235987	191/423 (45%)
CG12170	NP_649565.1	KAS_I_II	24..434	CDD:238430	190/420 (45%)
SPBC887.13c	NP_596487.1	fabF	2..422	CDD:274452	191/421 (45%)
SPBC887.13c	NP_596487.1	KAS_I_II	2..421	CDD:238430	190/420 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	215	1.000	Domainoid score	I586
eggNOG	1	0.900	-	-		E1_COG0304
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5820
Inparanoid	1	1.050	352	1.000	Inparanoid score	I478
OMA	1	1.010	-	-		QHG53767
OrthoFinder	1	1.000	-	-		FOG0002908
OrthoInspector	1	1.000	-	-		oto100855
orthoMCL	1	0.900	-	-		OOG6_100752
Panther	1	1.100	-	-	LDO	PTHR11712
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R883
SonicParanoid	1	1.000	-	-		X2728
TreeFam	0	0.000	Not matched by this tool.
	13	12.900