Protein Alignment CG31546 and CBR4

DIOPT Version :10

• Sequence 1: NP_730973.1
• Gene: CG31546 / 40691
• FlyBaseID: FBgn0051546
• Length: 264
• Species: Drosophila melanogaster
• Sequence 2: XP_006714454.1
• Gene: CBR4 / 84869
• HGNCID: 25891
• Length: 247
• Species: Homo sapiens
• Alignment Length: 269
• Identity: 82/269 - (30%)
• Similarity: 126/269 - (46%)
• Gaps: 46/269 - (17%)

  Fly    14 KVVLITGAASGIGAAAAEMFSKLGACLALVDREEEGLICVMKRCMKMGHEPYGIAGDLLKPPEIE 78
            ||..:.|.:.|||.|.|::.::.|..||::.|..||   .......:|.:....:.|:.|..:::
Human     3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEG---AKAAAGDLGGDHLAFSCDVAKEHDVQ 64

  Fly    79 CIARKTTERYEGKLDVLVNGAGIMPTGTLQSTELACFTHVMEANVRSGFYLTKLLLPQLLQCK-- 141
            ....: .|::.|:::.|||.|||...|.|..|:.......:..|          ||..:|.||
Human    65 NTFEE-LEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTN----------LLGSMLTCKAA 118

  Fly   142 ---------GSIVNVS----------SVCGLRAFPNLVAYNMSKAAVDQFTRSLALDLGPQGVRV 187
                     ||||||.          |:.||:.......|:.||..:..|:|:||.::..:.:||
Human   119 MRTMIQQQGGSIVNVGHRREMLLHKRSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRV 183

  Fly   188 NAVNPGVIRTNLQKAGGMDEQSYAEFLEHSKKTHALGRIGEPKEVAAAICFLASELASFVTGVTL 252
            |.|.||.:.|::.|  .:.|       ||.||...|||.||..|||.|:.||..  :.::||..|
Human   184 NVVAPGFVHTDMTK--DLKE-------EHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVL 237

  Fly   253 PVDGGKQVM 261
            .||||.|::
Human   238 VVDGGLQLI 246

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31546	NP_730973.1	Rossmann-fold NAD(P)(+)-binding proteins	11..261	CDD:473865	82/267 (31%)
CBR4	XP_006714454.1	Rossmann-fold NAD(P)(+)-binding proteins	3..243	CDD:473865	80/264 (30%)